Protein
Small-conductance mechanosensitive channel MscMJ
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Function
Small-conductance mechanosensitive channel that opens in response to stretch forces in the membrane lipid bilayer. Exhibits a sixfold preference for cations over anions. Non-rectifying.
Similarity
Belongs to the MscS (TC 1.A.23) family.
Sequence
MNMEIFGNSISNILIFVVITLLGIFIGKIVDKIVRNYLKKIIDKTKTKFDDIILESIDLPIIVLVVTLFFYFGLRFLILPDYILKLIDEAVKVVVILSATYFAVKFIDGIFEHYLIPLTEKTETELDEHIIKPLKKVVKILTILLGILTALSSVGYDITALLAGLGVGGLALALAMQDTIKNFIAGILILIDKPFSLGHWVKVKGAEGIVEEIGIRSTRIRTFDYTLITIPNSELLDSAIENLTVRDRRRVLMTIGLTYNTPVEKIKRAKEIIKEIVENHPATLPPYRVHFREYGDWSLNLRVEYFVRNMGFDYYLNAVDEINLKIKEEFEKEGIEMAFPTYTVYLEKDN