Protein
Probable lanosterol 14-alpha demethylase
Organism
Acanthamoeba polyphaga mimivirus
Function
Catalyzes the 14-alpha demethylation of obtusifoliol to 4 alpha-methyl-5 alpha-ergosta-8,14,24(28)-trien-3 beta-ol.
Similarity
Belongs to the cytochrome P450 family.
Sequence
MLFELSIGAIIGFLTLYLLKRFNESKNFITPDNLKKIPIVEGAVPVLGHGPAFSKDIMQFMKNCYKKYGSVFQLKIFRTNMVVLCDRKLSEEFFKSRENDMSLYDVLNRLFFGLAFSDKPDSLEFIIKMVKKTITIRYDDFAPKIMDEAQRLTKIMRESHSGKKLDMIPEIIKFVSRTSARCFIAMDIDDEFYDALNKFTNLLNKIVVLTYFVPHWLLNATLNRFMLRKYRMRMTKLLENEIEKYRTDLNKSDSLLFRKCVDHIDPETGATLTNQDIGDIVVCLLYVSSENTSLLATNCLIDLTLNPKYWDLIKSECSAMIALGDYKNLFKAPLLNSIVMESARLNSHVFALARKPKTVNRIGDYFVADNVDTISLCEPALMKFEIASDVYANPNSYDPVRFMAPRNEPKDSGHVMNWGKGVHECPGKQFAIYEVKAAIAYIVTNFERFEFNHNDLKINYFSPSAMCEKNISVEFIPSQQNIHNIVYKDRTYIVEHIKCNETSAWLIYNALDRQQQREYYQYTYEISTDSQEHKLIEKAGPHKPFPIAYDKLVYTGQSNCMTPTKWYDFASDIWELLTENYAELGFPIYDDKIRNFVPNSFYGQLYSVESIMPTHRDQHVDYGLSISIGSNCEFVIEDKTILLPSGSVLIGDFSKISHSVSKIFHEKPDHLSDFEFFNRVRFSAQIRSIDPDVQPLMTTQEFLDMISEY