Protein
Mitochondrial dynamics protein MID49
Function
Mitochondrial outer membrane protein which regulates mitochondrial organization (By similarity). It is required for mitochondrial fission and promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins (By similarity). Regulates DNM1L GTPase activity (By similarity).
Similarity
Belongs to the MID49/MID51 family.
Sequence
MAELQIRKKEKKSGDGIGTMVDFLLANARLVLGVGGAAMLGIATLAVKRLIDRATSPPSDKEAEEKAEQKSIEESWKEAVLKKASPTLRRKEDLEHHCAPLSLPDPSQKMPEATGTSQVKASDEIKKIPICFTLQERLLNYHTHHASVPEVQMEEARQLVLDIKKELQEFLHAKHPEMPFLALHLGGSFGNRLPMSCLDHACLIMPLVLEPDLWCVIPGQKTILSDPNFCMVKRIDLEYTSRGSSPWDRFLVGAYLSSRTMVQSLHKTIVGSINWPAIGTVLDCTIKPDITSDELKLEVVHPNGHMIIRILPMAVIKDADLLAHCCATAPAENLWQRSFYKKEVSRLQELDSSDSGIRLKCLQILKGICRDCPSLCHLNSTHLRHILLHLSTESSDWTETALADRFLQVLEELIGYLDKGFLPSYFNDKLNLFSSLKAEDIEELGYGLYQVFSEPDDVLKRER