MFM1

Mitochondrial inner membrane magnesium transporter MFM1

413 amino acids

Mitochondrial inner membrane magnesium transporter required for mitochondrial magnesium homeostasis. Modulates the conductance of the MRS2 channel. Involved in the splicing of mRNA group II introns in mitochondria by affecting mitochondrial magnesium concentrations, which are critical for group II intron splicing.

Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.

47.083 kDa

MRAFPRVLPFRHQRSYNNILLRTVRLFGSSLSSFDFSRQMPKVDPDNTAAMLLQKNLIQRNNMLYGYGSGTIRCTLLDSTGRAKSPLVEIKREDLVSKHGLLPRDLRKIEKSRKNDLVPSLLVRENSILISLLTVKALIKPDMVIIFDSAGSGITLNSEAHKDFINDMKLRLKNQETSELNSDPLPYEFRALETIFISALSNLTSEMKVLLTICKGVLQDLEFSITRDKLRFLLGQNKKLSSFNKKAVLVKDMLDDLLEQDDMLCDMYLTDKKAGKIRVQDDHTEIEMLLETYHNYVDEIVQKSESAISDVKTTEEIINIILDSNRNELMLLGIRYAIGMLSLGGALFLGSIYGMNLESFIEESNYAYLTVTILGLISTVWLYAKGIRHLHKLQRMTLLSKIKTDSVHELLKK

mfm1

M-factor

42 amino acids

M-factor is a mating pheromone produced by M-type mating cells. All three mfm genes contribute to the production of M-factor.

4.448 kDa

MDSMANSVSSSSVVNAGNKPAETLNKTVKNYTPKVPYMCVIA