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MEP4

Gene
MEP4
Protein
Extracellular metalloproteinase 4
Organism
Arthroderma otae (strain ATCC MYA-4605 / CBS 113480)
Length
649 amino acids
Function
Secreted metalloproteinase probably acting as a virulence factor.
Similarity
Belongs to the peptidase M36 family.
Mass
71.25 kDa
Sequence
MHGLLLAGLLALPSNVLGHPAEPPNSVNVTHRHIDTSAYFLPQLSLYNKSEDVAEYGGDNITGSSYSGGDHSASNLSSEDYVTVATSLLKATLPYASFRLIDDHYIGDSGIGHVHFRQTVYGIDIDNTDFNVNVGRDGKVFSYGSSFYEGEIPKANPVAKRDFSDPVNALIGAINTLNIPVTAAVGEVKTTPIEGNSTYMFKGTTGALTDPTAQLVYLQKDGGLHLTWRVETDVGDNWLLTYVDAKKNDQVHGVVDYVASAEYQVYPWGVNDPTDGERAHLYFPWFKTGSRNWHIDGRGWHTTTRGNNAIAQDNPSGGWEYEDNHRPTNPLLIFRYPYTQSMTPPASYRDASITQLFYTGNVYHDLLYILGFNEKAGNFQVNNWGKGGKGNDFTILNTQDGSGVNNANFATPPDGQPGRMRMYVWDTSTPYRDGSFEAGIVIHEYTHGVSNRLTGGPANSRCLSSLESGGMGEGWSDFFATVVHLKERDTRNKNYTIGEWASGRQGGIRKYPYSTDLHTNPLMYVDADGLESVHAIGTIWCTILNEVLWNLIERHGMGNVNKIKPTFKDGVPTDGRNLAMKLVLDGMALQPCLPNFVQARDAIIDADMNLTKGANRCELWKAFAKRGLGVGAAYNPEKRVGSSRVPGGC
Protein
Extracellular metalloproteinase 4: MEP4

Gene
MEP4
Protein
Extracellular metalloproteinase 4
Organism
Arthroderma otae
Length
649 amino acids
Function
Secreted metalloproteinase probably acting as a virulence factor.
Similarity
Belongs to the peptidase M36 family.
Mass
71.25 kDa
Sequence
MHGLLLAGLLALPSNVLGHPAEPPNSVNVTHRHIDTSAYFLPQLSLYNKSEDVAEYGGDNITGSSYSGGDHSASNLSSEDYVTVATSLLKATLPYASFRLIDDHYIGDSGIGHVHFRQTVYGIDIDNTDFNVNVGRDGKVFSYGSSFYEGEIPKANPVAKRDFSDPVNALIGAINTLNIPVTAAVGEVKTTPIEGNSTYMFKGTTGALTDPTAQLVYLQKDGGLHLTWRVETDVGDNWLLTYVDAKKNDQVHGVVDYVASAEYQVYPWGVNDPTDGERAHLYFPWFKTGSRNWHIDGRGWHTTTRGNNAIAQDNPSGGWEYEDNHRPTNPLLIFRYPYTQSMTPPASYRDASITQLFYTGNVYHDLLYILGFNEKAGNFQVNNWGKGGKGNDFTILNTQDGSGVNNANFATPPDGQPGRMRMYVWDTSTPYRDGSFEAGIVIHEYTHGVSNRLTGGPANSRCLSSLESGGMGEGWSDFFATVVHLKERDTRNKNYTIGEWASGRQGGIRKYPYSTDLHTNPLMYVDADGLESVHAIGTIWCTILNEVLWNLIERHGMGNVNKIKPTFKDGVPTDGRNLAMKLVLDGMALQPCLPNFVQARDAIIDADMNLTKGANRCELWKAFAKRGLGVGAAYNPEKRVGSSRVPGGC
Protein
Extracellular metalloproteinase 4: MEP4

Gene
MEP4
Protein
Probable extracellular metalloproteinase 4
Organism
Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371)
Length
643 amino acids
Function
Secreted metalloproteinase probably acting as a virulence factor.
Similarity
Belongs to the peptidase M36 family.
Mass
70.687 kDa
Sequence
MHGLLLAGLLALPLNVLAHPTESHSSGVSRRAIDITSYRLPQISKYTKSDAVPKQDGESFTTSSTGDDNVSSGDYVTTATNWLKKTLPKATYRLVNDHYIGDSGIGHVHFRQTAHGIDIDNTDFNVNIGRDGKVFSFGNSFYDGEIPKANPMVKRDFSDPVNALHGAIQTLNLPVTAKPENVKAKPVEGKENFKFEGTSGALSDPKAQLVYLQKDGGLVLSWKVETDVGDNWLLTYVDANKNDQVHSVVDYVSAAEYQVYPWGINDPTEGNRTSIHLPWLKTLSTDWHIDGKGWYPTTRGNNAIAQENPTGHPEYENNYRPKSPLFIFKYPYSLAMTPPSSYRDASITQLFYTTNVYHDVLYILGFNEKAGNFQINNWNKGGVGGDFAILNSQDGSGVNNANFATPPDGQPGRMRMYTWNASTPERDGCFEAGIVIHEYTHGVSNRLTGGPENSRCLAALESGGMGEGWSDFFATAIRLKPGDTRATDYTMGEWASNRPNGIRKYRYSTSLTTNPHMYVDADGLTSVHAIGTIWASMLYELLWNLIDKHGKGDVTKIRPVLKNGVPTDGRHLAMKIVLDGMALQPCLPNFVQARDAILDADKNLTQGSNKCEIWKAFAKRGLGVGAAFNQTKRTGSNELPAGC
Protein
Probable extracellular metalloproteinase 4: MEP4

Gene
MEP4
Protein
Extracellular metalloproteinase 4
Organism
Arthroderma benhamiae
Length
643 amino acids
Function
Secreted metalloproteinase probably acting as a virulence factor.
Similarity
Belongs to the peptidase M36 family.
Mass
70.641 kDa
Sequence
MHGLLLAGLLALPLNVLAHPTESHSSGISRRAIDITSYRLPQISKYTKSDAVPKQDDESFTTSSTGDDNVSSGDYVTTATDWLKKTLPKATYRLVNDHYIGDSGIGHVHFRQTAHGIDIDNTDFNVNIGRDGKVFSFGNSFYDGEIPKANPMVKRDFSDPVNALQGAIQTLNLPVTAKPENVKAKPVEGKENFKFEGTSGAFSDPKAQLVYLQKDGGLVLSWKVETDIGDNWLLTYVDANKNDKVHSVVDYVSAAEYKVYPWGINDPTEGNRTSIHLPWFKTLSTDWHIDGKGWYSTTRGNNAIAQENPTGGPEYENNYRPKSPLFIFKYPYSEAMTPPSSYRDASITQLFYTTNVYHDVLYILGFNEKAGNFQVNNWNKGGVGGDFAILNSQDGSGVNNANFATPPDGQPGRMRMYTWNASTPERDGCFEAGIVIHEYTHGVSNRLTGGPANSRCLAALESGGMGEGWSDFFATAIRLKAGDTRATDYTMGEWASNRPNGIRKYRYSTNLTTNPHMYVDADGLTSVHAIGTIWASMLYELLWNLIDKHGKGNVTKVRPVLKNGVPTDGRHLAMKLVLDGMALQPCLPNFVQARDAILDADKVLTQGSNKCEIWKAFAKRGLGVGAVFNPSKRTGSNELPAGC
Protein
Extracellular metalloproteinase 4: MEP4

Gene
MEP4
Protein
Extracellular metalloproteinase 4
Organism
Trichophyton equinum
Length
643 amino acids
Function
Secreted metalloproteinase probably acting as a virulence factor.
Similarity
Belongs to the peptidase M36 family.
Mass
70.668 kDa
Sequence
MHGLLLAGLLALPLNVLAHPTESHSSGISRRAIDITSYRLPQISKYTKSDAVPKQDDESFTTSSTGDDNVSSGDYVTTATDWLKKTLPKATYRLVNDHYIGDSGIGHVHFRQTAHGIDIDNTDFNVNIGRDGKVFSFGNSFYDGEIPKANPMVKRDFSDPVNALQVAIQTLNLPVTAKPENVKAKPVEGKENFKFEGTSGAFSDPKAQLVYLQKDGGLVPSWKVETDIGDNWLLTYVDANKNDKVHSVVDYVSAAEYKVYPWGINDPTEGNRTSIHLPWFKTLSTDWHIDGKGWYSTTRGNNAIAQENPTGGPEYENNYRPKSPLFIFKYPYSEAMTPPSSYRDASITQLFYTTNVYHDVLYILGFNEKAGNFQVNNWNKGGVGGDFAILNSQDGSGVNNANFATPPDGQPGRMRMYTWNASTPERDGCFEAGIVIHEYTHGVSNRLTGGPANSRCLAALESGGMGEGWSDFFATAIRLKAGDTRATDYTMGEWASNRPNGIRKYRYSTNLTTNPHMYVDADGLTSVHAIGTIWASMLYELLWNLIDKHGKGDVTKVRPVLKNGVPTDGRHLAMKLVLDGMALQPCLPNFVQARDAILDADKVLTQGSNKCEIWKAFAKRGLGVGAVFNPSKRTGSNELPAGC
Protein
Extracellular metalloproteinase 4: MEP4

Gene
MEP4
Protein
Extracellular metalloproteinase 4
Organism
Trichophyton rubrum
Length
643 amino acids
Function
Secreted metalloproteinase probably acting as a virulence factor.
Similarity
Belongs to the peptidase M36 family.
Mass
70.698 kDa
Sequence
MHGLMLAGLLALPLSVLGHPTESHSSGISRRAIDITSYRLPQISKYTKSDAVPKQDGESFTTSSTGNDNSSSGDYVTTATNWLKKTLPKATYRLVKDHYIGDSGIGHVHFRQTAHGIDIDNTDFNVNIGRDGKVFSFGNSFYDGEIPKANPMVKRDFSDPVNALHGAIQILNLPVTAKPENVKAKPVEGKENFKFEGTSGALSDPKAQLVYLQKDGGLVLSWKVETDVGDNWLLTYVDANKNDKVHSVVDYVSAAEYQVYPWGINDPTEGNRTTLHLPWLKTLSTDWHIDGKGWYSTTRGNNAIAQENPTGGPEYENNYRPKSPLFIFKYPYSKAMTPPSSYRDASITQLFYTTNVYHDVLYILGFNEKAGNFQINNWNKGGVGGDYAILNSQDGSGVNNANFATPPDGQPGRMRMYTWNASIPERDGCFEAGIVIHEYTHGVSNRLTGGPENSRCLAALESGGMGEGWSDFFATAIRLKPGDTRVTDYTMGEWASNRPNGIRKYRYSTSLTTNPHMYVDADGLTSVHAIGNIWASMLYELLWNLIDKHGKGDVTKIRPVLKNGVPTDGRHLAMKIVLDGMALQPCLPNFVQARDAILDADKNLTQGSNKCEIWKAFAKRGLGVGAVFNLSKRTGSNELPAGC
Protein
Extracellular metalloproteinase 4: MEP4

Gene
MEP4
Protein
Extracellular metalloproteinase 4
Organism
Trichophyton tonsurans
Length
643 amino acids
Function
Secreted metalloproteinase probably acting as a virulence factor.
Similarity
Belongs to the peptidase M36 family.
Mass
70.668 kDa
Sequence
MHGLLLAGLLALPLNVLAHPTESHSSGISRRAIDITSYRLPQISKYTKSDAVPKQDDESFTTSSTGDDNVSSGDYVTTATDWLKKTLPKATYRLVNDHYIGDSGIGHVHFRQTAHGIDIDNTDFNVNIGRDGKVFSFGNSFYDGEIPKANPMVKRDFSDPVNALQVAIQTLNLPVTAKPENVKAKPVEGKENFKFEGTSGAFSDPKAQLVYLQKDGGLVPSWKVETDIGDNWLLTYVDANKNDKVHSVVDYVSAAEYKVYPWGINDPTEGNRTSIHLPWFKTLSTDWHIDGKGWYSTTRGNNAIAQENPTGGPEYENNYRPKSPLFIFKYPYSEAMTPPSSYRDASITQLFYTTNVYHDVLYILGFNEKAGNFQVNNWNKGGVGGDFAILNSQDGSGVNNANFATPPDGQPGRMRMYTWNASTPERDGCFEAGIVIHEYTHGVSNRLTGGPANSRCLAALESGGMGEGWSDFFATAIRLKAGDTRATDYTMGEWASNRPNGIRKYRYSTNLTTNPHMYVDADGLTSVHAIGTIWASMLYELLWNLIDKHGKGDVTKVRPVLKNGVPTDGRHLAMKLVLDGMALQPCLPNFVQARDAILDADKVLTQGSNKCEIWKAFAKRGLGVGAVFNPSKRTGSNELPAGC
Protein
Extracellular metalloproteinase 4: MEP4

Gene
MEP4
Protein
Probable extracellular metalloproteinase 4
Organism
Trichophyton verrucosum (strain HKI 0517)
Length
643 amino acids
Function
Secreted metalloproteinase probably acting as a virulence factor.
Similarity
Belongs to the peptidase M36 family.
Mass
70.693 kDa
Sequence
MHGLLLAGLLALPLNVFAHPTESHSSGVSRRAIDITSYRLPQISKYTKSDAVPKQDGESFTTSSTGDDNVSSGDYVTTATNWLKKTLPKATYRLVNDHYIGDSGIGHVHFRQTAHGIDIDNTDFNVNIGRDGKVFSFGNSFYDGEIPKANPMVKRDFSDPVNALHGAIQTLNLPVTAKPENVKAKPVEGKENFKFEGTSGALSDPKAQLVYLQKDGGLVLSWKVETDVGDNWLLTYVDANKNDQVHSVVDYVSAAEYQVYPWGINDPTEGNRTTIHLPWLKTLSTDWHIDGKGWYPTTRGNNAIAQENPTGHPEYENNYRPKSPLFIFKYPYSPAMTPPSSYRDASITQLFYTTNVYHDVLYILGFNEKAGNFQINNWNKGGVGGDFAILNSQDGSGVNNANFATPPDGQPGRMRMYTWNASTPERDGCFEAGIVIHEYTHGVSNRLTGGPENSRCLAALESGGMGEGWSDFFATAIRLKAGDTRATDYTMGEWASNRPNGIRKYRYSTSLTTNPHMYVDADGLTSVHAIGTIWASMLYELLWNLIDKHGKGDVTKIRPVLKNGVPTDGRHLAMKIVLDGMALQPCLPNFVQARDAILDADKNLTQGSNKCEIWKAFAKRGLGVGAAFNQTKRTGSNELPAGC
Protein
Probable extracellular metalloproteinase 4: MEP4

Gene
MEP4
Protein
Extracellular metalloproteinase 4
Organism
Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893)
Length
642 amino acids
Function
Secreted metalloproteinase that allows assimilation of proteinaceous substrates and probably acts as a virulence factor.
Similarity
Belongs to the peptidase M36 family.
Mass
70.359 kDa
Sequence
MHGLLLAGLLALPLNVLAHPTESHSSGISRRAIDITSYRLPQISKYTKSDSLTGQDGQSFTASSADADTSSGDYVSTATNWLKKTLPNASYRLVNDHYIGDSGIGHVHFRQTAHGIDIDNTDFNVNIGRDGKVFSFGNSFYDGEIPKANPMVKRDFSDPVDALHGAIQTLNIPVTAKPENVKAKPVEGKESFKFEGTSGALSDPKAQLVYLQKDGGLVLSWKVETDVGDNWLLSYVDANDKGKVHSVVDYVSAAAYEVYPWGINDPTEGKRSTIHVPWFKTQSVDWHIDGKNWYPTTRGNNAIAQENPTGQREYENNYRPKSPLFIFKYPYSEAMSPPSSYRDASITQLFYTTNVFHDVLYILGFNEKAGNFQTNNWNKGGLGGDYAILNSQDGSGVNNANFATPPDGEPGRMRMYNWNASTPERDGCFEAGIVIHEYTHGVSNRLTGGPANSRCLAALESGGMGEGWSDFFATAIRLKNGDTRATDYTMGEWASNRPNGIRKYRYSTNLTTNPHMYVDADGLTSVHAIGTIWASMLYEMLWNLIDKHGKGDVSKVKPTLKNGVPTDGRHLAMKIVLDGMALQPCLPNFVQARDAIIDADKNLTGGSNKCEIWKAFAKRGLGVGAVYNPSKRTGSNELPAGC
Protein
Extracellular metalloproteinase 4: MEP4

Gene
MEP4
Protein
Neutral protease 2 homolog MEP4
Organism
Coccidioides posadasii (strain C735)
Length
412 amino acids
Function
Secreted metalloproteinase that allows assimilation of proteinaceous substrates. Shows high activities on basic nuclear substrates such as histone and protamine. May be involved in virulence (By similarity).
Similarity
Belongs to the peptidase M35 family.
Mass
45.091 kDa
Sequence
MFATAIVAVLLAAASSAFPHAAREASKDDANVSVQLSAVGNTMVKAVVTNRGDEAISVLRLNSVLDSFPCRRVDVYKEGKKMEFEGLLAHHDMQNLPDDVFATLNPGDFAENTFDIAETVDLSAGGPVTVLSEGVFLLARSDSTSISGMVQYRSNELKIDVDGVLAAKVESAGGLRRRNLDKRTSFYLDTCTPAAMKNLTALLKSTTDYADAGARAATNGSLATFETFFKKTDLRTRRPVASRFRAISNETSIIDGGIVRLTCSDDFCKGTINAIADSWISFITICPRFFSAYPPTSPECHATDQTSILLHEMTHMRHVYSPGTNDFAYGYDNVTKLPADQAINNADTFAIYAAGKFFFFWFFVPYPIASSIPGLIYFHRFLPWMLNGKVIGTCRRCMPTSLLRRHLGGKSL
Protein
Neutral protease 2 homolog MEP4: MEP4

Gene
MEP4
Protein
Extracellular metalloproteinase 4
Organism
Trichophyton soudanense
Length
392 amino acids
Function
Secreted metalloproteinase probably acting as a virulence factor.
Similarity
Belongs to the peptidase M36 family.
Mass
43.355 kDa
Fragment
single
Sequence
VHSVVDYVSAAEHQVYPWGINDPTEGNRTTLHLPWLKTLSTDWHIDGKGWYSTTRGNNAIAQENPTGGPEYENNYRPKSPLFIFKYPYSKAMTPPSSYRDASITQLFYTTNVYHDVLYILGFNEKAGNFQINNWNKGGVGGDYAILNSQDGSGVNNANFATPPDGQPGRMRMYTWNASIPERDGCFEAGIVIHEYTHGVSNRLTGGPENSRCLAALESGGMGEGWSDFFATAIRLKPGDTRATDYTMGEWASNRPNGIRKYRYSTSLTTNPHMYVDADGLTSVHAIGNIWASMLYELLWNLIDKHGKGDVTKIRPVLKNGVPTDGRHLAMKIVLDGMALQPCLPNFVQARDAILDADKNLTQGSNKCEIWKAFAKRGLGVGAVFNLSKRTGS
Protein
Extracellular metalloproteinase 4: MEP4

Gene
MEP4
Protein
Extracellular metalloproteinase 4
Organism
Trichophyton violaceum
Length
392 amino acids
Function
Secreted metalloproteinase probably acting as a virulence factor.
Similarity
Belongs to the peptidase M36 family.
Mass
43.381 kDa
Fragment
single
Sequence
VHSVVDYVSAAEYQVYPWGINDPTEGNRTTLHLPWLKTLSTDWHIDGKGWYSTTRGNNAIAQENPTGGPEYENNYRPKSPLFIFKYPYSKAMTPPSSYRDASITQLFYTTNVYHDVLYILGFNEKAGNFQINNWNKGGVGGDYAILNSQDGSGVNNANFATPPDGQPGRMRMYTWNASIPERDGCFEAGIVIHEYTHGVSNRLTGGPENSRCLAALESGGMGEGWSDFFATAIRLKPGDTRATDYTMGEWASNRPNGIRKYRYSTSLTTNPHMYVDADGLTSVHAIGNIWASMLYELLWNLIDKHGKGDVTKIRPVLKNGVPTDGRHLAMKIVLDGMALQPCLPNFVQARDAILDADKNLTQGSNKCEIWKAFAKRGLGVGAVFNLSKRTGS
Protein
Extracellular metalloproteinase 4: MEP4