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MED7

Gene
med7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
376 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
43.509 kDa
Sequence
MEPNEGVQLFSAFPPPPPYYKLFTRENIEKVISNMEKEAKHEDDANTLQPKTEEEIESLAKLFKKPSCLTSGTYQMFGDTWRLDEAIPSLKEFGIPELYKDIKDGEDEIEVVEYDPKSNAIVGTSFTRVHDYDKNSPIENEKILEDDQHTAMKEKDNESDKTMKDVEEKTEPSLKKEEEDIQMKEPLDSQDTGAVSASSVNEGFRADQKSKDGETSDLIKIPRRAYELRFLSRSLMLNFLELLGIMAKAPEQFPSKVENIRVLLLNLHHLINDYRPHQSRESLIMLLEKQLKHEESQVELLRTHNRQMTETLEKYKSLDFNMEKEGDVIQQLKSSIKKPLSGAEDEQKSRSMFSKNDEKLKKSLELMEDVIKRDLS

Gene
med7
Protein
Putative mediator of RNA polymerase II transcription subunit 7
Organism
Dictyostelium discoideum
Length
345 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
39.699 kDa
Sequence
MNTSQQQQQQQQQQQQQQQQQQQTPQQVENVSAFPPPPPFYKLYLNYKKDVDYSKPTTENSKKNDTPEGNESTIEKNIDNSDEMNIDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKATTSTNKKIELNKPLAPPLPPKVGANYVQFGQTYSTVDMLPSLDESGAKQLYPKGDIEPISELKKLNRSILFNYLQLLETLIENPKNYQSKIEDISLLFINFHHLLNSYRPHQARETLLSIMNEQIKQKNQSNESIKKALDICKESLMNSFKNLNIEDKQIDSATPLPTNITSPTKNLMSPTKLNNSQDVNMNENNDDDEDKEINWMDQLLDEMLKIN

Gene
MED7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Ustilago maydis (strain 521 / FGSC 9021)
Length
315 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
36.077 kDa
Sequence
MNGEYDYEDGAQHQDGARESAVAGASNTNQISTSFFPPPPQVYKKFTKRNLRYLEILNSHKLADDEPSWDLLSVTQRLERQNAILRQPGSSSKIDAEQLQDEEADMAAIQDQDCDKPMTDLPDFDLKAELEPPNVDWIEEDGGYTVFGQLWPIPDVTPTLQQLGIPVLYPLEGTDRKELLLTLLRTLLQTYREITGDLLKPAQPYDVWVPAVPDPNLTPEQQQQQMATNPGFWTQTTEAKDRLKHMQNVVVNMQFLINELRPVQAKETLKLIMQMQLERRKQEMQLIQERCATMRARVEELKKMLGKQSDCYGSS

Gene
MED7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
304 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
34.508 kDa
Sequence
MSTNNTTTNNEDLISSLYPPPPPYYKFFTKDNLQKLSTWQENNQTTTVSSEVKLEEENTDPDSNNSEENSIPPGELRFLIPPKQPEGPQYRGYGNIWLFEDKLPNLKDSQWEQLYNTSTSTFTSTSTSTANTNIITNTDTDINGNQEVDAGDSTGDENLTSETKIKELHKLMDSLLLNFLELIGILSIDPIKYDKKIHDINLILININHLLNTYRPHQSRESLIMLLKNQIDYKFLEIDQINKKCLDIKSKIKNLINERITVVSDGTTTNTTTTTKTTGLGDGDSIDEKEQLKQDIINRLLSSI

Gene
MED7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)
Length
276 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
31.789 kDa
Sequence
MADADAQRQAEEDANLQLPPYPHPPPFYLKFTTENKDRLDEIKKEDGIDTASDGGKSAQLSTEQILALPTELRYLIPPEPPADTEEFNVFGTINQLKDRDTFNGTMEYISQALAKLLPDWKYEQLYPTTDASNSASSTLDRQRYLFRFLRSILVAYIELLGIVAINPTDELKDDKLKDILTMVTNMHALINEYRPHQARETLISEMERQVEKKKMEIQGVRKMKERVGEVLEGFGREIPSEKAEDRTEEAAVTSEEERKRDAQRQMWQAMDEMLSQ

Gene
med7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Length
263 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
29.637 kDa
Sequence
MADAAQQRTLATAFAPPPPLWKHFTPDNLKRLEEIKKEASKGEDGKPQKKKWSPAELRALDLPPELRLLVPPAIPDTGHYSVFGELQNLSTALPSLKDQGITQLYPSSSPADTDRQSPSEPSRPLNHAYYLLKISKSLLLNFLEFVGVLSVSPEQFESKVEDLRNLFINAHHLLNLYRPHQARESLIMMMEEQLSRTKEEIQQMDKLKAEITGVLERLEADGIAAQSHPQQTDEDGRKESETSQKTIEDAQLVWDLLDGKIEG

Gene
MED7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)
Length
263 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
29.315 kDa
Sequence
MDNHEDDPNRVTALWPDPPSFWRDFTPENVERYDSLKEDYTHQQGLSADADADAVIRIPSIPEELINLQPPPEPTEGTWTLFTETQTLTETLQSLEEAGIQRLGPTSDIDRDSKHLDRGFQLKKLVKSLLLNYLELVGLMGYNPDHAAEKIEDLKILLLNFHHTLNEYRPHHAREQLIQIMHAHGDQMRAETAGIRSVVDKAKRMIEGLASIQVPQLDNTESDTGGKGAVGVGVGVGGAKAQRTRLERGREAVGWAGVEGDFA

Gene
med7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Length
261 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
29.681 kDa
Sequence
MAEAGKPRPLTAFAPPPPLWKHFTQDNLKRLEDIKKEASKGEDGKPRKKKWTPAELRALQLPPELRFLVPPEIPKSGQYSVFGELQSLSTTLPSLQEQGIEQLYPSTPTETDPDKPSQPSRPFNHAYYLLKISKSLLLNFLEFVGILSIAPEQFQSKVEDLRNLFINAHHLLNLYRPHQARESLIMMMEEQLNRSREEIQQMDKMHAEINGFLEQLKAQGIDIDSASKSREDVTAKRATGDQDANNANSSRLVWDILDGTD

Gene
med7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40)
Length
261 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
29.552 kDa
Sequence
MADAGQQRPLTAFAPPPPLWKHFTPDNLKKLDEIKKNASKGEDGKPQKKKWTPTELRALDVPPELHFLVPPEIPKSGHYSVFGELQSLSTALPSLQDQGITQLYPSPPTGDADREQPSEPSQPLNHAYYLLKISKSLLLNFLEFVGILSVAPEQFESKVEDLRNLFINAHHLLNLYRPHQARESLILMMEEQLSRTREEIQQMDKLKEEITGALEQLKKDGVDVDAAPIEAPDNDTKKPNVSEEKAIEDTRLVWELLDENN

Gene
med7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)
Length
261 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
29.614 kDa
Sequence
MAEAGQPRPLTAFAPPPPLWKHFTPDNLKRLEEVKKEASKGEDGKPRKKKWTPAELRALQLPPELRFLVPPEIPMSGQYSVFGELQSLSTTLPSLQEQGIEQLYPSTPTETDPNKPSQPSRPFNHAYYLLKISKSLLLNFLEFVGILSITPEQFQSKVEDLRNLFINAHHLLNLYRPHQARESLIMMMEEQLNRSREEIQQMDKMHAEINGFLEQLKAQGIDVDSASKSGENDTAKRTTGDQDANNANSSRLVWDILDGTD

Gene
med7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Length
260 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
29.26 kDa
Sequence
MAEAGQPRALPTAFAPPPPLWKHFTPGNLKKLEEIKREASKGEDGKARRKDWTPAELRALDLSPELGFLVPPEIPTKGHYSVFGELQSLSTALPSLQEQGIEQLYPSPPTETDREAPSQPSRPFNHAYYLLKISKSLLLNFLEFVGVLSVAPEQFQAKVEDLRNLFINAHHLLNLYRPHQARESLIMMMEEQLKRSREEIEQMDKLHTEIKGFLDQLKAQGVDVDSAAESVSKATKKDDTSNKRAAEDSGLIWDILGEID

Gene
med7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
Length
259 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
29.061 kDa
Sequence
MAESGQPSALTTAFAPPPPLWKHFTPENVKRLEEIKKEASKGEDGKPRKKTWTPAELRALDLPPELRFLVPPEVPTEGHYSVFGELQSLSTALPSLKDQGIEQLYPSSPAAESGRDTSEPSKPLNHAYYLLKISKSLLLNFLEFVGVLSICPEQFESKVNDLRNLFINAHHLLNLYRPHQARESLIMMMEEQLSQSREEIQQMDKLKAEITDALDRLRRQGVDVDSAAGAAVQEEKPTTAEAQISDHSRLVWDLLDGDN

Gene
med7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Length
259 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
29.318 kDa
Sequence
MAEPGRTFNTAFAPPPPLWKHFTPENLQRLENIKKEASKGEDGRRRKKEWSPAELRSLKIPPELRFLVPPEIPSEQYSIFGEVQNLSTALPSLEEQGITQLYPSSPKPDTKSGDSSQPAQPLNHAYYLLKISKSLLLNFLEFVGILSVAPEQFEPKVEDIRNLFINAHHLLNLYRPHQARESLIMMMEAQLARTKDEIQQMDKLKEEVNAVLDQLAAEGADVGSTIQSTTKDKKGVKPEDQIPEDSKLLWDILDGKLDD

Gene
MED7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)
Length
257 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
29.653 kDa
Sequence
MSTANGDLISSLYPPPPVYVKFFTTENLNKLQEWQRQQNDEEIETKQEEADDKDEKDNEKQNETQDTVPPGELRFLVPPQPPSGTHYRGYGNIWSFEDKLPSLKSANWEQLYKDDDESITSETKIKELHKLMDSLLLNFLELIGLASIDPSQYESKIKDISLILININHLLNTYRPHQSRESLIMLLRKQIDAKRASINQVEKVCSEVKQKLLKLTNIQDVYKKDSIVLPDNSDNSPMAENAESIKDEIIKKLLSEH

Gene
MED7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Coccidioides immitis (strain RS)
Length
256 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
29.25 kDa
Sequence
MEEGGQQKGITAAFPPPPPFWKKFTPENLERLEKAKREAEPQALSRKWSPEALHALKLAPELRYLVPPELPKEGSYSLFGEAQSLSTQLPSLEEQGIEQLYPSSLTNETAGPSPDHAYYLLKISKSLLLNFLELVGILSINPEQYEPKIEDIRNLFINAHHLLNLYRPHQSRESLITMMEEQLEQAKEEIREMEQTKERVEIYLRELEAEGRNVSPNDEPVQTPESGPHNTKTQTSESQANGEQVLWKLLDKVEES

Gene
MED7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Length
244 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
28.509 kDa
Sequence
MTSTNEDIISSLYPPPPPYFKYFTEQNLNNLEIWKNKAQDEMQIDKTDLEQVKEDQDIKPPGELKFLVPPKQPDADHYRGFGNLWSFEDKLPGLKESGWTQLYKDDDELITSNTKIDELHKLMDSLLLNFLELIGVVSIDPQQFHYKIEDLKLILININHILNTYRPHQSRESLIMLLRKQIDMKRNEISEIDKTSEDIKSKILKLVDTSYIGDQEDAKCDNDSTEDEESIKNNIIQKLLNQNV

Gene
med7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Danio rerio
Length
241 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
27.519 kDa
Sequence
MGEPQQVSALPPPPMQYIKEYTDENVRKGLAPKPPPPIRDSYMMFGNQFQCDDLIIRPLESQGIERLHPMQFDHKRELKKLNMSILVNFLDLLDILIKSPGSIKREEKLEDLKLLFVHMHHLINEYRPHQARETLRVMMEVQKRQRLETAERFQKHLERVVEMIQGCLSSLPDDLPLPNSSSMGEAGSAAGSSRLKTEPMDVDDVAGASCMVLQTDKNVPVKKDGVCDNDVVMCRIIDEMT

Gene
MED7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
Length
239 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
26.889 kDa
Sequence
MSSLPQEAALPITNTLFPPPPPYFQAFTDEAIERYETLTGKSLFVNDEKGKTKGKEKKSDDRDMSVDIRIQDLTEEEQNEKLELEGKLEKPRADWVNEDGRWMCFGTMYTTEPIIPTAQSIGLPPFIDPAVEPQESLPPLLHSFLHTLLLLLDTLTMTARTPNELAAAGWASEGDQYIQHLTNLSANMMVASNQLRSAQSEATLVLLMEKELEERRKQTEKLRSKCKEIASGIRALKGL

Gene
MED7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
Length
239 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
26.889 kDa
Sequence
MSSLPQEAALPITNTLFPPPPPYFQAFTDEAIERYETLTGKSLFVNDEKGKTKGKEKKSDDRDMSVDIRIQDLTEEEQNEKLELEGKLEKPRADWVNEDGRWMCFGTMYTTEPIIPTAQSIGLPPFIDPAVEPQESLPPLLHSFLHTLLLLLDTLTMTARTPNELAAAGWASEGDQYIQHLTNLSANMMVASNQLRSAQSEATLVLLMEKELEERRKQTEKLRSKCKEIASGIRALKGL

Gene
MED7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
235 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
26.747 kDa
Sequence
MERRKKQNEGLLSVYPPPPWYSRYFTDENVAKVKDLQSSDNSQLLEAPLKYLTPPSPPEAGAYHNFGDVWQVNDKLATLEDLGITQVYDGAAIRGEGQESGARVLELKKLTKSLLLAFVELTGIMGVSPEQFPAKFEHVRVLLINIHHILNEYRPHQARESLVTLMQQQINDKKQHVENIRQSCDKVRDTIRVLSKQFDQVDEFEETGGVTTEEVKYVSGKDKDLLVVKMAEQVL

Gene
MED7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Bos taurus
Length
233 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
27.278 kDa
Sequence
MGEPQQVSALPPPPMQYIKEYTDENIQEGLAPKPPPPIKDSYMMFGNQFQCDDLIIRPLESQGIERLHPMQFDHKKELRKLNMSILINFLDLLDILIRSPGSIKREEKLEDLKLLFVHVHHLINEYRPHQARETLRVMMEVQKRQRLETAERFQKHLERVIEMIQNCLASLPDDLPHSEAGMRVKTEPMDTDDSNNCIGQNEQQRENSGHRRDQIIEKDAALCVLIDEMNERP

Gene
MED7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Homo sapiens
Length
233 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
27.245 kDa
Sequence
MGEPQQVSALPPPPMQYIKEYTDENIQEGLAPKPPPPIKDSYMMFGNQFQCDDLIIRPLESQGIERLHPMQFDHKKELRKLNMSILINFLDLLDILIRSPGSIKREEKLEDLKLLFVHVHHLINEYRPHQARETLRVMMEVQKRQRLETAERFQKHLERVIEMIQNCLASLPDDLPHSEAGMRVKTEPMDADDSNNCTGQNEHQRENSGHRRDQIIEKDAALCVLIDEMNERP

Gene
Med7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Mus musculus
Length
233 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
27.205 kDa
Sequence
MGEPQQVSALPPPPMQYIKEYTDENIQEGLAPKPPPPIKDSYMMFGNQFQCDDLIIRPLESQGIERLHPMQFDHKKELRKLNMSILINFLDLLDILIRSPGSIKREEKLEDLKLLFVHVHHLINEYRPHQARETLRVMMEVQKRQRLETAERFQKHLERVIEMIQNCLASLPDDLPHSEAGMRVKAEPMDTDDNSNCPGQNEQQRESSGHRRDQIIEKDAALCVLIDEMNERP

Gene
MED7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Sus scrofa
Length
233 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
27.165 kDa
Sequence
MGEPQQVSALPPPPMQYIKEYTDENIQEGLAPKPPPPIKDSYMMFGNQFQCDDLIIRPLESQGIERLHPMQFDHKKELRKLNMSILINFLDLLDILIRSPGSIKREEKLEDLKLLFVHVHHLINEYRPHQARETLRVMMEVQKRQRLETAERFQKHLERVIEMIQNCLASLPDDLPHSEAGMRVKAEPMDADDSNNCTGQSDQQRENSGHRRDQIIEKDAALCVLIDEMNERP

Gene
MED7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
230 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
26.512 kDa
Sequence
MSREESVSGANDVSSLYPPPPPYIKYFTSENVEKLKEYNERREEGESAENELDFLIPPPMPSSGSYRAFGSVWQIKDHLPDLETMGITQLYKKTSEGEAEVTDYQYKIKELRRLSYSLLLNFVELVGVLSVNPELYESKVENIRTILVNIHHLLNEYRPHQSRESLIMLLEEQLEHKKQEVANIELVCQQVTEKLKQVQTLLKESQSQSQSQSQSQSQSQSQSQLQSDSQ

Gene
med7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Xenopus tropicalis
Length
229 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
26.474 kDa
Sequence
MGEPQQVSALPIPPMQYIKEYTDENIRKGLAPKPPLPIKDSYMMFGNQFQCDDLIIRPLETQGIERLHPMQFDHKKELRKLLMSILVNFLDMLDILIRSPGSIRREEKLEDLKLLFVHMHHLINEYRPHQARETLRVMMEVQKRQRLETAERFQKHLERVVEMIQNCLASLPNDLPLSDGAVSVKTEPMDVREPCTDHHAGPQEAAAASLKETTIDKDAAMCVIIDEMT

Gene
MED7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
222 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins.
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
25.585 kDa
Sequence
MSNDPGNEVSSLYPPPPPYVKFFTQSNLEKLPKYKEKKAASAKQTAPNNSNGGSEEEITCALDYLIPPPMPKNQQYRAFGSIWQVKDQLPDLESMGLTQLYKKSTENESTNYQYKIQELRKLLKSLLLNYLELIGVLSINPDMYERKVENIRTILVNIHHLLNEYRPHQSRESLIMLLEEQLEYKRGEIREIEQVCKQVHDKLTSIQDTLRTGSQSPPSSSQ

Gene
MED7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Drosophila melanogaster
Length
220 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). Required for activated transcription of the MtnA, MtnB and MtnD genes.
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
25.707 kDa
Sequence
MSNQETQVSSLPMPPERYIANYTDENIRRNRAPRPPPPPAQHEVYSMFGIQYNNDEMIRSLESQNIKRLIPIHFDRRKELKKLNHSLLVNFLDLIDFLILNPDSPRRTEKIDDISLLFVNMHHLLNEFRPHQARETLRVMMEMQKRQRVETAARFQKHLERVREIVNTAFSALPVLDDDDDSGGAKIKTEVDPLEANAAAKNDPSYQHDRMLCKLVDAIE

Gene
MED7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Aedes aegypti
Length
219 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
25.529 kDa
Sequence
MENTDAIQVSSFPLPPAQYYKLYTDENVRNNRAPKPPAPIQGTYQMFGQQFSTEDNIIRPLEAQGFKRLYPQHFDRRKELKKLNHSLLVNFLDLIDLLVHNPDSPQRAEKIEDLNLLFVHIHHLLNEFRPHQARETLRVMMELQKRQRQETTQRFQNHLEKVREMVNNAFASLPDPAESDRLNSTVEPMDTGDDGEAGKSRGEGCHPLDRLMCELVDKM

Gene
MED7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Anopheles gambiae
Length
219 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
25.23 kDa
Sequence
MSNAEAIQVSSLPLPPAQYINLYTDENIRKNRAPKPPAPIQDAYTMFGSPFSNDDNIIRPLESQGFKRLYPQHFDRRKELKKLNHSLLVNFLDLIDLLVHYPDSPRRAEKIEDLSLLFVHIHHLLNEFRPHQARETLRVMMELQKRQRIETAQRFQNHLEKVREMVKNAFASLPDLTDADRLAGGLEPMDVGESGDLAGGRGEGCHPLDRLMCELVDRM

Gene
MED7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
213 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
24.993 kDa
Sequence
MSDKNEVSSLYPPPPPFIQFFTEENSKLFRECGKDEEKLAKCTTKQREQLKYFVKPELPRDGSYRAFGNVWKIKDELPELSQMGIEQLYRKRESVTELENGTTTEVEPSPQDSQSGTNYENKIQESKKLMKSLLLNFLELIGILGVDSSRYEKKLDEIRVIAINIHHLLNEYRPHQSRESLIMLFEEQLEHKRKEMEHINKVCDEVESKLAQL

Gene
MED7
Protein
Mediator of RNA polymerase II transcription subunit 7
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
199 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 7 family.
Mass
23.075 kDa
Sequence
MSDSNNISSLYPPPPPYVKFFTKDNLERLAEYQSSHVTTDPEQITCELDFLIPPPVPSAGHYRAFGSVWQVKDELPDLETVGLRNLYDDRGQHGNNYQYKIKELHKLLKSLLLNMLELVSVLSVNPERFPDKVEHIRTILFNIHHLLNEYRPHQSRESLIMLLEEQLEHKKEEIANIHAICDKVQAKLAAMCKQYIADD