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MED31

Gene
MED31
Protein
Mediator of RNA polymerase II transcription subunit 31
Organism
Aedes aegypti
Length
218 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 31 family.
Mass
24.145 kDa
Sequence
MANKMVGKGKLPVESEDAQKLRFQAELEFVQCLANPNYLHFLAQRGFFKDSNFINYLKYLLHWKDPEMAKYLKYPMCLYFLDLLQYEHFRREIVNAQCCKFIDDQAILLWQHYTRRRTRLTSLGTTSLTGLAVGGQPVGGGVQGPLLSNEPLPMANNNNNTNSTNANNPQAPGQQQQQNGAPMIQQNGLSNNTGMSGGVMGSGARDGGGVNLSGQKVS

Gene
MED31
Protein
Mediator of RNA polymerase II transcription subunit 31
Organism
Drosophila melanogaster
Length
204 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for activated transcription of the MtnA gene.
Similarity
Belongs to the Mediator complex subunit 31 family.
Mass
23.531 kDa
Sequence
MAKMYGKGKTAIESEELQKRRWQIELEFVQCLSNPNYLNFLAQRGFFKDQSFINYLKYLQYWKEPDYAKYLMYPMCLYFLDLLQYEHFRREIVNSQCCKFIDDQAILQWQHYTRKRIKLIENVTAAQQQQQQLQQQQQQANGMEAATGGESAAPTPNVNGSASTADSQQTSSALQPVQAQPGNPQQQQQINGVASGANIKLELN

Gene
MED31
Protein
Mediator of RNA polymerase II transcription subunit 31
Organism
Arabidopsis thaliana
Length
196 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Similarity
Belongs to the Mediator complex subunit 31 family.
Mass
22.819 kDa
Sequence
MASPEEMGDDASEIPSPPKNTYKDPDGGRQRFLLELEFIQCLANPTYIHYLAQNRYFEDEAFIGYLKYLQYWQRPEYIKFIMYPHCLYFLELLQNPNFRTAMAHPANKELAHRQQFYYWKNYRNNRLKHILPRPLPEPVPPQPPVAPSTSLPPAPSATAALSPALSPMQYNNMLSKNDTRNMGATGIDRRKRKKGI

Gene
med31
Protein
Putative mediator of RNA polymerase II transcription subunit 31
Organism
Dictyostelium discoideum
Length
176 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 31 family.
Mass
21.437 kDa
Sequence
MSSSSPINENDNGNIENNNETNITENGDNGESIDKKDDNIVLPYENDEEEANYLRFIMELEFIQCLSNPRYLNYLAQNRYFQDKAFVNYLVYLQYWKKPEYAKFIVYPQSLYFLDLLQEERFRQELNHSQSTDFIHEQQFYHWQYYRNNRMSIKEQELQQQQQQQQQQQVQPPTTV

Gene
med31
Protein
Mediator of RNA polymerase II transcription subunit 31
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
139 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 31 family.
Mass
16.896 kDa
Sequence
METKWLLSKVPDDKSRFEIELEFVQMLSNPWYLNFLAQHKYFEDEAFLQYLEYMEYWREPEYVKFIIYPTCLHMLTLLKNPQFRNDISRADLSKQVNDEIYYEWLGKGLQQYGSADDATLSQPQQEEDEKKVDVKKENE

Gene
med31
Protein
Mediator of RNA polymerase II transcription subunit 31
Organism
Danio rerio
Length
136 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 31 family.
Mass
16.521 kDa
Sequence
MAGVMETDEQARQRFQLELEFVQCLANPNYLNFLAQRGYLREKPFVNYLKYLLYWKEPEYAKFLKYPHCLHMLELLQYEHFRKELVNAQCAKFIDEQQILHWQHYSRKRTRLQQALAEQQQQQQPQAPSHANTTSK

Gene
MED31
Protein
Mediator of RNA polymerase II transcription subunit 31
Organism
Bos taurus
Length
131 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 31 family.
Mass
15.789 kDa
Sequence
MAAAVAMETDDAGNRLRFQLELEFVQCLANPNYLNFLAQRGYFKDKAFVNYLKYLLYWKEPEYAKYLKYPQCLHMLELLQYEHFRKELVNAQCAKFIDEQQILHWQHYSRKRMRLQQALAEQQQQNNASGK

Gene
MED31
Protein
Mediator of RNA polymerase II transcription subunit 31
Organism
Homo sapiens
Length
131 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Similarity
Belongs to the Mediator complex subunit 31 family.
Mass
15.805 kDa
Sequence
MAAAVAMETDDAGNRLRFQLELEFVQCLANPNYLNFLAQRGYFKDKAFVNYLKYLLYWKDPEYAKYLKYPQCLHMLELLQYEHFRKELVNAQCAKFIDEQQILHWQHYSRKRMRLQQALAEQQQQNNTSGK

Gene
Med31
Protein
Mediator of RNA polymerase II transcription subunit 31
Organism
Mus musculus
Length
131 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 31 family.
Mass
15.771 kDa
Sequence
MAAAVAMETDDAGNRLRFQLELEFVQCLANPNYLNFLAQRGYFKDKAFVNYLKYLLYWKEPEYAKYLKYPQCLHMLELLQYEHFRKELVNAQCAKFIDEQQILHWQHYSRKRVRLQQALAEQQQQNNTAGK

Gene
med31
Protein
Mediator of RNA polymerase II transcription subunit 31
Organism
Xenopus tropicalis
Length
128 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 31 family.
Mass
15.697 kDa
Sequence
MAAAMETDEQQRIRFQLELEFVQCLANPNYLNFLAQRGYFKDKSFVNYLKYLLYWKDPEYAKYLKYPQCLHMLELLQYEHFRKELVNAQCAKFIDEQQILHWQHYSRKRMRMQQALAEQQQQNNTSGK