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MED30

Gene
MED30
Protein
Mediator of RNA polymerase II transcription subunit 30
Organism
Drosophila pseudoobscura pseudoobscura
Length
325 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 30 family.
Mass
36.309 kDa
Sequence
MWKYGQNQGNQGPAGGGGGAPNMMPMGGFMQGGGGMQGGGGMQHGNMPQMHMTPQQQQQQQQMNMMGGPGGMQMNPNAVGPTGLMPGMSPQHQMQQQQQMMQGVPMSMPPQQAMQQQMMGPQQGLGMGGSSGPQQQQQLQQQQQQSNLQQQQQQHNVGSGGAPGAGGVGNNMLAISQPNPHKEINIVQLSRLGQETVQDIASRFQEVFSALKNIQPTSHRDNNTEKKVQEYFRTIRLLFKRVRIIYDKCNDAVMDYMNAESLIPYKDEPEPRIETSQCDEYRKVLQENHEYIETVKLKNRQLREIIDRTRIIIWEINTMLAMRRS

Gene
MED30
Protein
Mediator of RNA polymerase II transcription subunit 30
Organism
Drosophila melanogaster
Length
318 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Similarity
Belongs to the Mediator complex subunit 30 family.
Mass
35.301 kDa
Sequence
MWKYGQNQGNQGPSSGGGGGGGPNMMPMGGFGMQHGNMQQMHMSPQHQQQQQQMGMMGGPGSMQMNPQGPGGPGGLMPGMSPQHQMQQQQQQQMMQQQMMVPQQGVGVGVGMGGGVGMGGGGVVPQQQQQQPQQNMPQQNIPQQQQQLNPVAGIPPGGAGGSNNMLAISQQNPHKEINIVQLSRLGQETVQDIASRFQEVFASLKGIQPTSHRENSSEKKVQEYFRTIRLLFKRVRIIYEKCNDAGMDYMSAESLIPYRDEPEPRIEPSLCDEYRKVLQENHELIETVKLKNRQLREIIDRTRIIIWEINTMLAMRRS

Gene
MED30
Protein
Mediator of RNA polymerase II transcription subunit 30
Organism
Aedes aegypti
Length
306 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 30 family.
Mass
33.622 kDa
Sequence
MSGQYPSGYQSPSGHRGNFNSPMMQQQLNQMGVPNQMGMMGFNQGNVMQNQQQMQSGGVQSGPDIGMGQNIQQQQQPNPSQGTGQGQQQQPGQGQAQGQQQQNPQQSPQLGMAAGGQAVSSAAQSATGTVGGAPPGQPNAGPVASTQAASNVQQKEFNLLTLCRIGQETVQDIVSRFQEVFGLLRGIQPPNGTNAGLSSSNDKKAKVQEQFRTIRLLFKRLRLLYDKCNDNCQQGMEYTHVESLIPLKGEPERAEPIHTEEYKKALQENRELIEIVMLKNKQLREIIDKIRLTIWEINTMLSMRRC

Gene
med30
Protein
Putative mediator of RNA polymerase II transcription subunit 30
Organism
Dictyostelium discoideum
Length
255 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 30 family. Highly divergent.
Mass
28.143 kDa
Sequence
MDKIEIEEELICSLAVKGEKSIHKLLLNILAIVKQLKTIQSDPVLTYQVSTKAQQQLQSQQLQQPQSIPSSTNNSTNTNTNNSTTTTTTSSTSSTTTPTTTTSTTSPLNSKDSTATTTTKEQPSSPTLPTLNLNFVNDNDKIKELNQNCIQSILALQKTIKEISLLETKISQKPKDNIDNDDTIMKDDNNNSSTSAPTTTTINIEKQDQTSLSNELERLKMDAYQKNCVIKKLIDNMRLLQLSINSMNRTSTGTD

Gene
MED30
Protein
Mediator of RNA polymerase II transcription subunit 30
Organism
Bos taurus
Length
193 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 30 family.
Mass
21.691 kDa
Sequence
MSTPPLAASGMAPGPFAGPQAQQAAREVNTASLCRIGQETVQDIVYRTMEIFQLLRNMQLPNGVTYHTGTYQDRLAKLQDHLRQLSILFRKLRLVYDKCNENCGGMDPIPVEQLIPYVEEDGSKDDRAGPPRFASEERREIAEVNKFQVNSKGTQPYLHMYPFSSKLPSHSGCRIPLSRIPCAVQNSNRRINS

Gene
MED30
Protein
Mediator of RNA polymerase II transcription subunit 30
Organism
Arabidopsis thaliana
Length
189 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Similarity
Belongs to the plant Mediator complex subunit 30 family.
Mass
19.814 kDa
Sequence
MLQKQVSTTTTMTTQELAMEGEKQLEETIEAAFQIISAMNDELCNPSLWSTSATPSSAATTTGSNGSALVSADAAAIDGTSHHSESAGGGGGGGSGNSVLDEASLRYKNSVTSLRAVLAAIPNSQKAKASEMQNGLGSPESEDEIEKLEEQALSLRMEIAKKNVHVKELIDKLRELIADISTWQSPCSV

Gene
med30
Protein
Mediator of RNA polymerase II transcription subunit 30
Organism
Xenopus laevis
Length
184 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 30 family.
Mass
20.871 kDa
Sequence
MSTPPLSGPGMGAAAGPGGFPGAQAATAAREVNTASLCRIGQETVQDIVFRTMEIFQLLRNMQLPNGVTYHTVTYQDRLGKLQEHLRQLSILFRKLRLVYDKCNENCAGLDPVPIEQLIPYVEEEYSKHDDRGIASQLRFASEEKREILEVNKKLKQKNQQLKQIMDQLRNLIWDINSMLAMRN

Gene
MED30
Protein
Mediator of RNA polymerase II transcription subunit 30
Organism
Homo sapiens
Length
178 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Similarity
Belongs to the Mediator complex subunit 30 family.
Mass
20.277 kDa
Sequence
MSTPPLAASGMAPGPFAGPQAQQAAREVNTASLCRIGQETVQDIVYRTMEIFQLLRNMQLPNGVTYHTGTYQDRLTKLQDNLRQLSVLFRKLRLVYDKCNENCGGMDPIPVEQLIPYVEEDGSKNDDRAGPPRFASEERREIAEVNKKLKQKNQQLKQIMDQLRNLIWDINAMLAMRN

Gene
Med30
Protein
Mediator of RNA polymerase II transcription subunit 30
Organism
Mus musculus
Length
178 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 30 family.
Mass
20.358 kDa
Sequence
MSTPPLAPTGMASGPFGGPQAQQAAREVNTATLCRIGQETVQDIVYRTMEIFQLLRNMQLPNGVTYHTGTYQDRLTKLQDHLRQLSILFRKLRLVYDKCNENCGGMDPIPVEQLIPYVDEDGSKNDDRAGPPRFASEERREIVEVNKKLKQKNQQLKQIMDQLRNLIWDINAMLAMRN

Gene
med30
Protein
Mediator of RNA polymerase II transcription subunit 30
Organism
Danio rerio
Length
174 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 30 family.
Mass
20.201 kDa
Sequence
MTTPPLAQFSGQQQQQTQAARDVNTASLCRIGQETVQDIVLRTMEIFQLLRNMQLPNGVTYHPNTHQDRLGKLQEHLRTLSVLFRKLRLVYDKCNENCAGLEPIPSEQLIPYVEDDSSKLEDRMANQLRAASEERREVLEVNKKLKQKNQQLKMIMDQLRNLIWEINSMLAVRS