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MED22

Gene
MED22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Gallus gallus
Length
203 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
23.049 kDa
Sequence
MAQQRVLPQSKETLLQSYNKRLKDDVKSIMDNFTEIIKTAKIEDETQVSRATQSEQDNYEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAINQRNQQLRSLQEECDKKLIALRDEISIDLYELEEEYYSSSYSLCDSNDLPLCEAYWREDFDMPSPESLSMPLTTATAEQSIATSQSSTPSHPHVNGHGAGPTDHS

Gene
MED22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Gallus gallus
Length
203 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
23.049 kDa
Sequence
MAQQRVLPQSKETLLQSYNKRLKDDVKSIMDNFTEIIKTAKIEDETQVSRATQSEQDNYEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAINQRNQQLRSLQEECDKKLIALRDEISIDLYELEEEYYSSSYSLCDSNDLPLCEAYWREDFDMPSPESLSMPLTTATAEQSIATSQSSTPSHPHVNGHGAGPTDHS

Gene
MED22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Bos taurus
Length
201 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Mass
22.381 kDa
Sequence
MAQQRALPQSKETLLQSYNKRLKDDVKSIMDNFTEIIKTAKIEDETQVSRATQGEQDNYEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAIDQRNQQLRALQEECDRKLIALRDEVSIDLYELEEEYYSSSSSLCEANDLPLCEAYWRLDPDTDSTDCLSAPLLASPEPSAGGPLQAAAPTHSHAGGPGPTEHA

Gene
med22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Xenopus laevis
Length
201 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
22.946 kDa
Sequence
MSQQRILPQSKETLLQSYNKRLKDDIKSIMDNFTEIIKTAKIEEEHQVSRSTQGEQDNYEMHVRSANIVRAGESLMKLVSDLKQFLILNDFPSVNESINQRNQQLRTLREECDKKLIALRDDIAIDLYELEEEYYSSSYSVCDPSDLPLCEVYWNRESTASSPEDLSVPLAPIMAEASTVTSQIHTPPHLNGHGAGMTEHT

Gene
MED22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Bos taurus
Length
201 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Mass
22.381 kDa
Sequence
MAQQRALPQSKETLLQSYNKRLKDDVKSIMDNFTEIIKTAKIEDETQVSRATQGEQDNYEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAIDQRNQQLRALQEECDRKLIALRDEVSIDLYELEEEYYSSSSSLCEANDLPLCEAYWRLDPDTDSTDCLSAPLLASPEPSAGGPLQAAAPTHSHAGGPGPTEHA

Gene
med22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Xenopus laevis
Length
201 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
22.946 kDa
Sequence
MSQQRILPQSKETLLQSYNKRLKDDIKSIMDNFTEIIKTAKIEEEHQVSRSTQGEQDNYEMHVRSANIVRAGESLMKLVSDLKQFLILNDFPSVNESINQRNQQLRTLREECDKKLIALRDDIAIDLYELEEEYYSSSYSVCDPSDLPLCEVYWNRESTASSPEDLSVPLAPIMAEASTVTSQIHTPPHLNGHGAGMTEHT

Gene
MED22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Homo sapiens
Length
200 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
22.221 kDa
Sequence
MAQQRALPQSKETLLQSYNKRLKDDIKSIMDNFTEIIKTAKIEDETQVSRATQGEQDNYEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAIDQRNQQLRTLQEECDRKLITLRDEISIDLYELEEEYYSSSSSLCEANDLPLCEAYGRLDLDTDSADGLSAPLLASPEPSAGPLQVAAPAHSHAGGPGPTEHA

Gene
Med22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Mus musculus
Length
200 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
22.282 kDa
Sequence
MAQQRALPQSKETLLQSYNKRLKDDIKSIMDNFTEIIKTAKIEDETQVSRATQGEQDNYEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAIDQRNQQLRALQEECDRKLITLRDEVSIDLYELEEEYYSSSSSLCEANDLPLCEAYWRLDLDADSADGLSAPLLASPETGAGPLQSAAPVHSHGGGPGPTEHT

Gene
Med22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Rattus norvegicus
Length
200 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
22.312 kDa
Sequence
MAQQRALPQSKETLLQSYNKRLKDDIKSIMDNFTEIIKTAKIEDETQVSRATQGEQDNYEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAIDQRNQQLRALQEECDRKLITLRDEVSIDLYELEEEYYSSSSSLCEANDLPLCEAYWRLDLDTDSADGLSAPLLASPETGAGPLQSAAPVHSHGGGPGPTEHT

Gene
med22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Takifugu rubripes
Length
200 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
22.923 kDa
Sequence
MATQRVLPQSKETLLQSYNKRLKDDIKSILENFTEIIKTAKIEDETQVSRPAQAEQDHYEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNDAISLQNQQLRSLQEECDKKLISLRDEIAIDLYELEEEYYSSSYSQWDTDLPLCEAYHRVDNWASPSSSSSSTQGDQEEVEILPSQETEPQHHLNGQGTSSLEKM

Gene
MED22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Homo sapiens
Length
200 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
22.221 kDa
Sequence
MAQQRALPQSKETLLQSYNKRLKDDIKSIMDNFTEIIKTAKIEDETQVSRATQGEQDNYEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAIDQRNQQLRTLQEECDRKLITLRDEISIDLYELEEEYYSSSSSLCEANDLPLCEAYGRLDLDTDSADGLSAPLLASPEPSAGPLQVAAPAHSHAGGPGPTEHA

Gene
Med22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Mus musculus
Length
200 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
22.282 kDa
Sequence
MAQQRALPQSKETLLQSYNKRLKDDIKSIMDNFTEIIKTAKIEDETQVSRATQGEQDNYEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAIDQRNQQLRALQEECDRKLITLRDEVSIDLYELEEEYYSSSSSLCEANDLPLCEAYWRLDLDADSADGLSAPLLASPETGAGPLQSAAPVHSHGGGPGPTEHT

Gene
Med22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Rattus norvegicus
Length
200 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
22.312 kDa
Sequence
MAQQRALPQSKETLLQSYNKRLKDDIKSIMDNFTEIIKTAKIEDETQVSRATQGEQDNYEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAIDQRNQQLRALQEECDRKLITLRDEVSIDLYELEEEYYSSSSSLCEANDLPLCEAYWRLDLDTDSADGLSAPLLASPETGAGPLQSAAPVHSHGGGPGPTEHT

Gene
med22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Takifugu rubripes
Length
200 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
22.923 kDa
Sequence
MATQRVLPQSKETLLQSYNKRLKDDIKSILENFTEIIKTAKIEDETQVSRPAQAEQDHYEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNDAISLQNQQLRSLQEECDKKLISLRDEIAIDLYELEEEYYSSSYSQWDTDLPLCEAYHRVDNWASPSSSSSSTQGDQEEVEILPSQETEPQHHLNGQGTSSLEKM

Gene
med22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Danio rerio
Length
198 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
22.681 kDa
Sequence
MSTPRVLPQSKETLLQNYNKRLKDDIRSILDNFTEIIKTAKVEDETQVSRATQAEQDHFEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAISLRNQQLRTLQEECDKKLISLRDEIAIDLYELEEEYYSSSCGQWDGVELPLCEAFHRQDSWGSPEMTSDPSHANHEVSDHLGSQESMQRHRNGSGTSEQS

Gene
med22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Danio rerio
Length
198 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
22.681 kDa
Sequence
MSTPRVLPQSKETLLQNYNKRLKDDIRSILDNFTEIIKTAKVEDETQVSRATQAEQDHFEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAISLRNQQLRTLQEECDKKLISLRDEIAIDLYELEEEYYSSSCGQWDGVELPLCEAFHRQDSWGSPEMTSDPSHANHEVSDHLGSQESMQRHRNGSGTSEQS

Gene
med22
Protein
Putative mediator of RNA polymerase II transcription subunit 22
Organism
Dictyostelium discoideum
Length
149 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
17.283 kDa
Sequence
MNTGGNNSLPPQTRGEVLFRDQQFFQKQIDSKIMQLLENYHNIIKISKVNDPLKNASEIYEMETRTSNMLNAGEGLLKIIEELKQNLILNDFSTMAEEVRIQNLVFHKENERTNKSIKLISEELSRSLKELEDEYYNSSYKLPPPSSSK

Gene
med22
Protein
Putative mediator of RNA polymerase II transcription subunit 22
Organism
Dictyostelium discoideum
Length
149 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
17.283 kDa
Sequence
MNTGGNNSLPPQTRGEVLFRDQQFFQKQIDSKIMQLLENYHNIIKISKVNDPLKNASEIYEMETRTSNMLNAGEGLLKIIEELKQNLILNDFSTMAEEVRIQNLVFHKENERTNKSIKLISEELSRSLKELEDEYYNSSYKLPPPSSSK

Gene
MED22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Drosophila melanogaster
Length
143 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
16.594 kDa
Sequence
MASGSRTTILPQSKEALLKSYNARLKDDVRSMLENFEEILKLARRESHSQISKTTQCEQDALEMQVRAANMVRAGESLMKLVADLKQYLILNDFHSVNEAITNNSQLFRNTQSECDKKLMKLRDEMAMDLYDLEEEYYTSIFK

Gene
MED22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Drosophila melanogaster
Length
143 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
16.594 kDa
Sequence
MASGSRTTILPQSKEALLKSYNARLKDDVRSMLENFEEILKLARRESHSQISKTTQCEQDALEMQVRAANMVRAGESLMKLVADLKQYLILNDFHSVNEAITNNSQLFRNTQSECDKKLMKLRDEMAMDLYDLEEEYYTSIFK

Gene
MED22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Aedes aegypti
Length
138 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
16.225 kDa
Sequence
MQRNLTQSKEALLKSYNTRLKEDVRSMLDNFEEIVRLAKGENETQFSKMTQCEQDTYEMQVRASNIVRAGESLMKLVSDIKQYLILNDFHSVNEAICSSSQLYRSTQMDRDNKLMAVRDDMAADLYDLEEEYYTSMYK

Gene
MED22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Anopheles gambiae
Length
138 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
16.162 kDa
Sequence
MQRNLTQSKEALLKSYNSRLKEDIRSMRENFEEIIRLAKGENDTQLSKITQCEQDTYETQVRAANIVRAGESLMKLVSDIKQYLILNDFHSVNEAICSNSTLYRTTQIDRDNKLMAVRDDMAADLYDLEEEYYTSIYK

Gene
med22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
136 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
15.382 kDa
Sequence
MSSDSFQRQLVQRTNTLNSSIDNATLTILSRFQDILDIAINEGKDKYTVAPEVYQIECHTVSMVRAVEQLLDVSRQIKSYWLTNSLSTSFPTVDYSEPDLEKVKRTLTKLQNHLLEVSLIEPEASETTEAPTVSDT

Gene
med22
Protein
Mediator of RNA polymerase II transcription subunit 22
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
136 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Similarity
Belongs to the Mediator complex subunit 22 family.
Mass
15.382 kDa
Sequence
MSSDSFQRQLVQRTNTLNSSIDNATLTILSRFQDILDIAINEGKDKYTVAPEVYQIECHTVSMVRAVEQLLDVSRQIKSYWLTNSLSTSFPTVDYSEPDLEKVKRTLTKLQNHLLEVSLIEPEASETTEAPTVSDT