med18

Putative mediator of RNA polymerase II transcription subunit 18

251 amino acids

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).

Belongs to the Mediator complex subunit 18 family.

28.507 kDa

MFQQNKHHQQQQQQQQQQGVVQSGVASATVNNPSESIVAGNIYECSLHGILSTPSSTFIQRAKGMMRCEHPVSYKEMVFKSTVQSAGPSWAEGSILPSEIHVRYEKNTVYVRYVGVPQIKDNINAMIRNVVDIKSSETFFIYLENLGYVKDYEYFVDGYQYSTYNLSLFLVNHRRVLNDGTKGELLNKHSMVELQCLSGEEGFVAAAEYLNTYAEYLYPFVELIKFDHRLLTAENSNTPTTNVNVVGGYNR

MED18

Mediator of RNA polymerase II transcription subunit 18

219 amino acids

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors (PubMed:22021418, PubMed:24451981). Involved in the regulation of histone H3 lysine tri-methylation (H3K36me3). Associates with the promoter, coding and terminator regions of target genes suggesting its function in transcription initiation, elongation and termination. Multifunctional protein which regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea and A.brassicicola), flowering time and responses to hormones (e.g. abscisic acid ABA and ethylene) through interactions with distinct transcription factors (PubMed:24451981).

Belongs to the Mediator complex subunit 18 family.

23.365 kDa

MSMECVVQGIIETQHVEALEILLQGLCGVQRERLRVHELCLRSGPNLGVVSSEVRLLCDLDQPEPTWTVKHVGGAMRGAGADQISVLVRNMIESKVSKNALRMFYALGYKLDHELLKVGFAFHFQRTAHISVSVSSVNKMPKVHAIDEAVPVTPGMQIVDVTAPATSENYSEVAAAVSSFCEFLAPLVHLSKPSISTGVVPTAAAAAASLMSDGGGTTL

MED18

Mediator of RNA polymerase II transcription subunit 18

217 amino acids

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Belongs to the Mediator complex subunit 18 family.

24.673 kDa

MAIVSSARESLSHAMNNRFLPNLEYLLQGSILDSAVEHLMHRLKGLCDNVDTSPEPFHDLEVCMSLRQPNANQPLLLRVRRALGRDAPFQMRYLGNPEVDLRRPTLVRSCMDCACTNGILEFLTEMGFRLEFEYIAKGYMFRKGRMKITVSKLIKIVPGKQQDMANEPISQSYIVELSVVAPTGQENVGEEMRVFAEQLKPLVQLEKIDYKRLGGMP

MED18

Mediator of RNA polymerase II transcription subunit 18

215 amino acids

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).

Belongs to the Mediator complex subunit 18 family.

24.276 kDa

MTTSATPMAAVDLLQQALNSNIIPNQEYLLQGSILDSAAEHLLHRLRGLCDNVDTGPEAFADYEMCLSLKVPNEKTPVMTVRVRKAQDTDAPYQLRYIGQPELGDRNRPTLVRSSLDIACTPHVVDFLTEMGFRVDFEYITKGYMFRKGRMKVTVSKIFKVNSSEPISQSYLVELSVLAPTGQDVIADDMRIFAEQLKPLVQLEKIDYKRFAQMP

MED18

Mediator of RNA polymerase II transcription subunit 18

211 amino acids

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).

Belongs to the Mediator complex subunit 18 family.

23.867 kDa

MGAQVNAAELLQQALSSNIIPNQEFLLQGSILDSAAENLLHRLRGLCDNVDASPETFSDIEMCFSLKLPTEKTPVMTVRVRRAQDVEAPLQLRYIGQPELGDRTRPTLVRSSLDIACTPHVIDFLTEMGFRLDFEYSTKGYMFRKGRMKITVSKILKNMTEPISQSYLVELSVLAPKGQDAIAEDMRIFAEQLKPLVQLEKIDYKRFAQMP

MED18

Mediator of RNA polymerase II transcription subunit 18

208 amino acids

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Belongs to the Mediator complex subunit 18 family.

23.663 kDa

MEAPPVTMMPVTGGTINMMEYLLQGSVLDHSLESLIHRLRGLCDNMEPETFLDHEMVFLLKGQQASPFVLRARRSMDRAGAPWHLRYLGQPEMGDKNRHALVRNCVDIATSENLTDFLMEMGFRMDHEFVAKGHLFRKGIMKIMVYKIFRILVPGNTDSTEALSLSYLVELSVVAPAGQDMVSDDMKNFAEQLKPLVHLEKIDPKRLM

Med18

Mediator of RNA polymerase II transcription subunit 18

208 amino acids

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).

Belongs to the Mediator complex subunit 18 family.

23.645 kDa

MEAPPVTMMPVTGGTINMMEYLLQGSVLDHSLESLIHRLRGLCDNMEPETFLDHEMVFLLKGQQASPFVLRARRSMDRAGAPWHLRYLGQPEMGDKNRHALVRNCVDIATSENLTDFLMEMGFRMDHEFVAKGHLFRKGIMKVVVYKIFRILVPGNTDSTEALSLSYLVELSVVAPAGQDMVSDDMRNFAEQLKPLVHLEKIDPKRLM

med18

Mediator of RNA polymerase II transcription subunit 18

208 amino acids

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).

Belongs to the Mediator complex subunit 18 family.

23.21 kDa

MEAPPVTTMPVSGGTINMMEYLLQGSILDQGLESLLHRLRGLCDNMEPETFADHESVYLLKGQQASPFVLRARRPLDRPGAPWHLRYLGQPEAGDRSRHTLVRNCVDIATSDVLPEFLQEMGFRMDHEFVARGHLFRKGVMKVAVYKVFRVLVSGAAEGAEPLSLSYLVELSAVAPAGQDNIADEVRGFAEQLRPLVQLEKIDPKRVM

med18

Mediator of RNA polymerase II transcription subunit 18

208 amino acids

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).

Belongs to the Mediator complex subunit 18 family.

23.208 kDa

MEAPPVTTMPVSGGTINMMEYLLQGSILDQGLESLLHRLRGLCDNMEPETFADHESVYLLKGQQASPFVLRARRPLDRPGAPWHLRYLGQPEAGDRSRHTLVRNCVDIATSDVLPEFLQEMGFRMDHEFVARGHLFRKGVMKVAVYKVFRVLVAGAAEGAEPLSLSYLVELSAVAPAGQDNIADEVRGFAEQLRPLVQLEKIDPKRLM

MED18

Mediator of RNA polymerase II transcription subunit 18

208 amino acids

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).

Belongs to the Mediator complex subunit 18 family.

23.682 kDa

MEAPPVTMMPVTGGTINMMEYLLQGSVLDHSLESLIHRLRGLCDNMEPETFVDHEMVFLLKGQQASPFVLRARRSLDRAGAPWHLRYLGQPEMGDKNRHALVRNCVDIATSENLTDFLMEMGFRMDHEFVARGHLFRKGIMKIVVYKIFRILVPGNTDNTEALSLSYLVELSVVAPAGQDMVSDDMRNFAEQLKPLVHLEKIDPKRLM

med18

Mediator of RNA polymerase II transcription subunit 18

208 amino acids

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).

Belongs to the Mediator complex subunit 18 family.

23.289 kDa

MEAPPVTVMPVTGGTINMMEYLLQGSVLDQSLESLLHRLRGLCDNMEPESFADHELVYLLKGQQGNPFILRARRSLLDPSVPWHLRYLGQPEVGDKSRHALVRNCVDVAASHSLPDFLNEMGFRMDHEFVAKGQVFRKGVMKVVVSKLSRVLVPGNTDNTEPLSLSYLVELSVLAPAGQDTVSEDMRSFAEQLKPLVHLEKIDPKRLM

med18

Mediator of RNA polymerase II transcription subunit 18

207 amino acids

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Belongs to the Mediator complex subunit 18 family.

24.027 kDa

MQELYLLGVVPSRRFEAVVNSLSKTLDGPKTILEFWVVYRPKDVPPNLPRQPDSWLRLCSNIESHDETDTEWSKNTQWSMYLEGNSEPKREDKCGIRPVNRAKLTNGSVTEFVEKMGYEFSHEYIIQGLEYFFFDTTVRIYQTLIPSQQRSIKPPFHPMNEEQPWILHVYTHVADASNQVAMAKAEANLTKVKTLLSAFCDLKNVRL