MEAK7

MTOR-associated protein MEAK7

468 amino acids

Activates an alternative mTOR signaling to regulate cell proliferation and migration.

52.115 kDa

MGNAESNAYRNHLSRFLPEEQSDVDGLFDTLSGSSSSAAAKNGKAMKKTMTLEALKAYMREPLPEQMTVRLYNGMRSIDLTGKSSALSDHVAKEQFVIFMSNLLKGNADEKITIIMRMISTTEGPVKGKEIQEFTEDLIKSVVHVLSYRKELKGWTLENTRDSAGGIKALSSQLLSELKLADGTKAVSPQLMEMSFDRSVIEDWVYRVPQISAFLSVVLRQGLHVLHSLPDQTKDIVNLVPGCKGIKGRIVSLFDIPSIIYINSHLPAELQHKWRLLFSSKLHGESFSQLCAHIVNKGPCVVILKDTDGFIFGGFASHSWEVKPQFQGDNRCFLFSVFPSLAVYTYTGYNDHYMYLNHGQQTMPNGLGMGGQHDYFGLWVDSDYGKGHSKAKPRCTTYNSPQLSAKENFTLDALEVWAVGDMPESAETKGKKSILDVDPEAQALLEMTGKSRHSEGLREPIEDEDDDN

meak7

MTOR-associated protein MEAK7

460 amino acids

Activates an alternative mTOR signaling to regulate cell proliferation and migration.

52.084 kDa

MGNTESGSHQKGLSRILPEEKAEIEQFFENMCRMQSGPKKSVGLQYFQDALRNSLPCSISQRIFDGIQSVRTNSKSSTMSAEISKEQFLVFYVDLLRGTAEEKSQVICDMISCNNSEHMKGHQVQKFLEDIIAAVIYVLKQQSLLKGWNLENMRDCTLGTQGLAMQLLSQLQSIDGQKFERQELLDSPCSKSCIEDWLYKIPMISLFVRVMLTVGLSILKHHTEHQKDMKTLLPKCTGMKNTSFVSLLDLPAVMHLNYYLPYEVQHKWRLLFSSQIHGESFSQLCGHILDQGPCLLIVKDSDGFVFGGFASQSWKVKPQFQGDSRCFLFSISPRLDVYTYTGYNDHYMYLNRAQQSLPNGLGMGGQHEYFGFWIDSNFGIGHSKAKPSCTTYNSPQLSAKEEFSIHTVEVWAVGDVPEHLLAKNPRSILDSDTEARALLEMAGQTRQSDGLREVTEEDES

MEAK7

MTOR-associated protein MEAK7

456 amino acids

Activates an alternative mTOR signaling through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration (PubMed:29750193). Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome (PubMed:29750193).

50.994 kDa

MGNSRSRVGRSFCSQFLPEEQAEIDQLFDALSSDKNSPNVSSKSFSLKALQNHVGEALPPEMVTRLYDGMRRVDLTGKAKGPSENVSQEQFTASMSHLLKGNSEEKSLMIMKMISATEGPVKAREVQKFTEDLVGSVVHVLSHRQELRGWTGKEAPGPNPRVQVLAAQLLSDMKLQDGKRLLGPQWLDYDCDRAVIEDWVFRVPHVAIFLSVVICKGFLILCSSLDLTTLVPERQVDQGRGFESILDVLSVMYINAQLPREQRHRWCLLFSSELHGHSFSQLCGHITHRGPCVAVLEDHDKHVFGGFASCSWEVKPQFQGDNRCFLFSICPSMAVYTHTGYNDHYMYLNHGQQTIPNGLGMGGQHNYFGLWVDVDFGKGHSRAKPTCTTYNSPQLSAQENFQFDKMEVWAVGDPSEEQLAKGNKSILDADPEAQALLEISGHSRHSEGLREVPDDE

Meak7

MTOR-associated protein MEAK7

455 amino acids

Activates an alternative mTOR signaling through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration. Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome.

50.845 kDa

MGNAKSLSGQKMASRFLPEEQAEVDKLFDVLSSSEGGVATGTFSLEAMKSHVKEALPPAMVTRLYNGMQRVKPTDRTLGSCRSVSREQFTAFLSQLLRGSCEEKGLMVMNMISDAEGPTKTRDVQKFTEDLVASVAHVLTHRHELRGWTCRKSEVPPDSMQAMVAQLLSEMKFQDGYKFQGPQCLDQVCDQAMIEEWVFHVPHVGMFLSVVVHRGLCLLGSSFDPSTLVPECLADQGGRFESILDVLSVIYLSSHLAPEHRQRWRLLFSTQLHGQSFSQLCSHITSQGPSLLVLEDRDGYVFGGFASCSWEVKPQFQGDNRCFLFSIAPRMATHLHTGYNNHFMYLNYGQQTMPNGLGMGGQHHYFGLWVAADFGKGHSKAKPACTTYNSPQLSAQEDFLFDKMEVWGLGNLLEEYEGKNKKSVLDSNPEARSLLEISGRARHSEGLREVPRDED

meak7

MTOR-associated protein MEAK7

450 amino acids

Activates an alternative mTOR signaling to regulate cell proliferation and migration.

49.949 kDa

MGNGDSVVAQKRLARFRPDERPAVEGTFDRLHGARSSASAGKTSKGLSLDMLQLTMGKMASESMIKRVFQGLHSIDPGVPLHPGDGVSREQLLIFLADVLRGTAEERAPLVLAMAEGAKATVTTTEQIRGFMEDLVYAAVQTLAHKGHLRAWHPERMGDGAQGVKLLAEQLTSELKPSDQNSCDIACLEDWLFRIPMMAMFLELLIGEGLGVVLPSRPPPTLLPPCQFAPWTDLRCVLSLPLLMFLSPLLPEGHSAPWRMLFSTKMHGESFTRLLGSCKSRGPTVLLVKDTKGYIFGGFSSQSWEVKPQFQGDSRCFLFSVFPYMRVFTCTGYNDHYMYLNQGQQTMPNGLGMGGQHGYFGLWLDYDFGHGHSRARPRCTTYGSPQLSADEDFKLDTLEVWGVGKLPEEQEEDEKKKSILDADLEVQAMMEMTGKTLHSQGLREPEEDED