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MEAF6

Gene
meaf6
Protein
Chromatin modification-related protein MEAF6
Organism
Danio rerio
Length
192 amino acids
Function
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (By similarity).
Similarity
Belongs to the EAF6 family.
Mass
21.838 kDa
Sequence
MAMHAKATPPQIPDTRRELSELVKRKQELAETLVNLERQIYAFEGSYLEDTQMYGNIIRGWDRYLTNQKNSNSKTDRRNRKFKEAERLFSKSSVTSVAAVCALGGIPDHMNEKREPGSGTESDTSPDLQNQENEPSQEDTEEADGALQDLKPQKAASTSSGSHHSSHKKRKNKNRHRFDMKMNKKPRADYSA

Gene
MEAF6
Protein
Chromatin modification-related protein MEAF6
Organism
Bos taurus
Length
191 amino acids
Function
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (By similarity).
Similarity
Belongs to the EAF6 family.
Mass
21.676 kDa
Sequence
MAMHNKAAPPQIPDTRRELAELVKRKQELAETLANLERQIYAFEGSYLEDTQMYGNIIRGWDRYLTNQKNSNSKNDRRNRKFKEAERLFSKSSVTSAAAVSALAGVQDQLIEKREPGSGTESDTSPDFHNQENEPNQEDPEDLDGSVQGVKPQKAASSTSTGSHHSSHKKRKNKNRHRIDLKLNKKPRADY

Gene
MEAF6
Protein
Chromatin modification-related protein MEAF6
Organism
Homo sapiens
Length
191 amino acids
Function
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
Similarity
Belongs to the EAF6 family.
Mass
21.635 kDa
Sequence
MAMHNKAAPPQIPDTRRELAELVKRKQELAETLANLERQIYAFEGSYLEDTQMYGNIIRGWDRYLTNQKNSNSKNDRRNRKFKEAERLFSKSSVTSAAAVSALAGVQDQLIEKREPGSGTESDTSPDFHNQENEPSQEDPEDLDGSVQGVKPQKAASSTSSGSHHSSHKKRKNKNRHRIDLKLNKKPRADY

Gene
Meaf6
Protein
Chromatin modification-related protein MEAF6
Organism
Mus musculus
Length
191 amino acids
Function
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (By similarity).
Similarity
Belongs to the EAF6 family.
Mass
21.649 kDa
Sequence
MAMHNKTAPPQIPDTRRELAELVKRKQELAETLANLERQIYAFEGSYLEDTQMYGNIIRGWDRYLTNQKNSNSKNDRRNRKFKEAERLFSKSSVTSAAAVSALAGVQDQLIEKREPGSGTESDTSPDFHNQENEPAQEDPEDLDGSVQGVKPQKAASSTSSGSHHSSHKKRKNKNRHRIDLKLNKKPRADY

Gene
meaf6
Protein
Chromatin modification-related protein MEAF6
Organism
Xenopus tropicalis
Length
191 amino acids
Function
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (By similarity).
Similarity
Belongs to the EAF6 family.
Mass
21.615 kDa
Sequence
MAMHNKATPPQIPDTRRELAELVKRKQELAETLANLERQIYAFEGSYLEDTQMYGNIIRGWDRYLTNQKNSNSKNDRRNRKFKEAERLFSKSSVTSAAAVSALAGVQDQLIEKREPGSGTESDNSPDFQNQENEPSQDDTEDLDGSLSGVKPQKAASSANSGGHHSSHKKRKNKNRHRIDLKLNKKPRSDY

Gene
meaf6
Protein
Chromatin modification-related protein MEAF6
Organism
Xenopus laevis
Length
188 amino acids
Function
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (By similarity).
Similarity
Belongs to the EAF6 family.
Mass
21.172 kDa
Sequence
MAMHNKATPTQIPDTRRELAELVKRKQELAETLANLERQIYAFEGSYLEDTQMYGNIIRGWDRYLTNQKNSNSKNDRRNRKFKEAERLFSKSSVTSAAAVSSLAGVQDQLIEKREPGSGTESDNSPDFQNQENEPSQDDTEDLDGSLSGVKPQKAASSANSGGHHSSHKKRKNKNRHRLADKLLRSVI

Gene
MEAF6
Protein
Chromatin modification-related protein MEAF6
Organism
Gallus gallus
Length
182 amino acids
Function
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (By similarity).
Similarity
Belongs to the EAF6 family.
Mass
20.458 kDa
Sequence
MAALHAKAGGPPQIPDTRRELAELVKRKQELAETLANLERQIYAFEGSYLEDTQMYGNIIRGWDRYLTNQKNSNSKNDRRNRKFKEAERLFSKSSVTSAAAVSALAGVQDQLIEKREPGSGTESDTSPDFHNQENEPSQEDAEELDGSVQGVKPQKAASSTSGSHHSSHKKRKNKNRHRYVY