Protein
DNA polymerase processivity factor
Organism
Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987)
Function
Plays an essential role in viral DNA replication by acting as the polymerase accessory subunit. Associates with the viral polymerase to increase its processivity and forms high-affinity direct interactions with DNA. Facilitates the origin-binding protein UL9 loading onto DNA thus increasing its ability to assemble into a functional complex capable of unwinding duplex DNA (By similarity).
Similarity
Belongs to the herpesviridae DNA polymerase processivity factor family.
Sequence
MAGITMGSEHMYDDTTFPTNDPESSWKIVLAGEKFMTASAALKTIVGCVKNPLITFSDDGLMIQGTVCGQRMFVPIDCTSFSEYEWRGPTAIFLALTDSRRTLLDAFKCDKKKVVEVCFTFRGEPPCRHLTQTVTYANDGCSFSSTIVKYELWSASIICPQKTPDATFSLNKQQLSKILTVAAKVQHEELIFALKAEGGFYAGTICDVISFDIDGSAMVQYPYNATSHASSALIVACGKKKTNKSIAVTAYGSGKPFCLALEDTNAFRNVVQKIKTGAAGADLGFYTTCDPPMLCVRPHVFGSPTAFLFCNSDCMSIYELEEVSAVSGAIKSKRISEYFPKVSNIGSRKRGPSSPPFEREGKLAKVINQ