Protein
Capsid scaffolding protein
Organism
Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987)
Function
Assembly protein: Plays a major role in capsid assembly. Acts as a scaffold protein by binding major capsid protein. Multimerizes in the nucleus such as major capsid protein forms the icosahedral T=16 capsid. Cleaved by assemblin after capsid completion. The cleavages products are evicted from the capsid before or during DNA packaging.
Similarity
Belongs to the herpesviridae capsid scaffolding protein family.
Sequence
MNPADHPSVYVAGYLALYGADESDELNIDRKDIRAAIPTPAPLPINIDHRRDCTVGAVLALIDDEHGLFFLGKINCPVMVRTLETAASQEIFSELDNLKPDDKLLYIITNYLPSVSLSSRRLAPGETADETFLAHVALCLLGKRIGTIVTYDLTPEEAIEPFRKLSPNSKATLLSQGKETERLLGEMVWYPSKNAITKALLGTAVNNMLLRDRWQIISERRRMAGITGQKYLQASSFTALTDSMTSNNVSVTHPICENANPGNIQKDEEMQVCISPAQTSETLNAGVLSGCNDFHRLPHSDPASTSDQTNLQSLIEPSMNTQSSRPPGDDFIWVPIKSYNQLVSRNASQPTNIPDIAITSNQPPFIPPALMNTSISGQHSIPSGYAQYGYPTPVGTHNSLLPLGPVNQMGGFQYGPQVYPLSYGQSPLEAKLTALLECMTKEKRPVDEEHRGDDMHTTREERGRRGRKRPYEFDRSIESDLYYPGEFRRSNFSPPQASSMKYEETTGGRHDLSQTGPVLNSLMGAVTSLQKEVERLNGGNLPISNAQSSYGVPNGMHAPVYYSYPPPGTHPTVSWPMGVERPMPSTEGKTSTNSTVIPVPVSDPEAGRNVPITATISQERSDGIQKESIEQSRDTMNASAVAGIHRTSDAGVDVFINQMMAHQ