MDM1

Gene

MDM1

Protein

Structural protein MDM1

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

1127 amino acids

Function

Essential for mitotic growth. Mediates organelle inheritance.

Similarity

Belongs to the sorting nexin family.

Mass

129.981 kDa

Sequence

MPKFPQFRLILVLFYLISMIQWSVITFSLGFFLNVCIFAYFVFFKSLPDLPKPQPRFVDIVPESSNTVDVDKELKSVEGLIQDGNAQIGKELESIVNLIIKDFVQPWFTKIDKNSDAEFLKVIKWRLLQTLLVVKDKLMKNDSASLIVLKLLPIFNKHFSTFCDAREAVLSDLTLERHKSANIDLQIAVEFNKNYKIHKSLSLKPNALQKEIEKSIRKTVIGLLPHLFDNDELDSLLVFTLMTEVLTTCIISPLIFKFTDPDSWNLRIVSLSQNYFEEKHKVHKIRRMLSKELQDHRKVMNDVANKDVGEPSSEKLELNAEYTGKQFEHYLNQLDSLLDLSDIKYVAYSLALKIYQLKENEHLTKENLKYKKRLLLSLNLIESKLSFPGSEIDTASKKLAREANYPDLNMDNGIVLKEMASFLTSITLKDIVDDSEFLPFFESFLGSVPETQGSTFLEYSQTIESFKNPLEDATSEDIISGYSGISTMQLQEISSKFFHNNNLQNMKLLDEGLVKNIILFRNSFQINNDEDTFILARKSVLLLQTEAIKYLDDRFLPLFKKTPSFLKMLSTSHIISTDIYAHFLSRIGGVNNPEQNKIIKDNVKTDFMNPVRIFANPGITDALDNIVNGSGSKPHKSRISSNPRYSQLFGSENDNIFKDKLFDDENDNTSEISVVEDQLDHPRNMEKVSVSSGNSGLNPSQFYGSNNFRDNIASLTISIDQIEKELELLRHLILKADLTNNQMQLKILKKSQRTLLKELEMKELLKQQYMVQENGNSLFRKTKIYIRSYFSENSSNGLKEITYYIINIHHFNNGQVSSWDMARRYNEFFELNTYLKKNFRDLMRQLQDLFPSKVKMSLKYHVTKTLLYEERKQKLEKYLRELLSISEICEDNIFRRFLTDPTPFKLNKEYMHDDILEEPLHEPIGSSNSTSNSSSVVDLQSSEDGGELNFYEDERHFFTDSGYPFYSQNKSFVKQICDLFISLFALNKANAGWLRGRAIITVLQQLLGSTIEKYIKVSIQKLRSEDQVFEAIVTFKNMLWGDNGLFERKRNETAEATRSEGERLRTEQLALTSLQRLFADTCGRVVGLRDSHEAAGRVHAMLQNPYLNASLLLEALDAILLDIICND

Protein

Structural protein MDM1: MDM1

Gene

MDM1

Protein

Nuclear protein MDM1

Organism

Pongo abelii

Length

724 amino acids

Function

Microtubule-binding protein that negatively regulates centriole duplication. Binds to and stabilizes microtubules.

Similarity

Belongs to the MDM1 family.

Mass

81.888 kDa

Sequence

MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPYHDPQISKSLEWNGAISESNVVASPEPEAPETPKSQEAEQKDVTQERVHSLEASRVPKRTRSHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGLDRLLRKKAGLTVVPSYNALRNSEYQRQFVWKTSKETAPAFSANQVFHNKSQFVPPFKGNSIIHETEYKRNFKGLSPVKEPKLRNDLRENRNLETVSPEKKSNKIDDPLKLEAEMELKDLHQPKKKLAPWKHQRLGKVNSEYRAKFLSPAQYLYKAGAWTRVKGNMPNQGSLNAMWYAEVKELREKAEFYRKRVQGTHFSRDHLNQILSDSNCCWDVSSTTSSEGTISSNIRALDLAGDPTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPREKEEEDDDEEEGDRKTGKQAVRGEQEKLDVHEKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKKESHAVSLLTSPAAGIKTVDPLPLREDSEDNIPKFAEATLPVSKIPEYPTNPPGQSPSPPHVPSYWYPSRRIQGSLRDPEFQHNVRKARMNNLRLPQHEAFNDEDEDRLSEISARSAASSLRAFQTLARAKKRKENFWGIT

Protein

Nuclear protein MDM1: MDM1

Gene

Mdm1

Protein

Nuclear protein MDM1

Organism

Rattus norvegicus

Length

719 amino acids

Function

Microtubule-binding protein that negatively regulates centriole duplication. Binds to and stabilizes microtubules.

Similarity

Belongs to the MDM1 family.

Mass

80.698 kDa

Sequence

MPVRFKGLSEYQRNFLWKKSYLSESYNPSVGQKYTWAGLRSDQLGITKEPSFISKRRVPYYDPQISKYLEWNGTVRENDALAPPEPQIIRTPKPQEAEQREDANHETVLPQEASRVPKRTRSHSADSRAEGASDGVEKHQDVTKNHSLVNADVELRPSTKPLPESIEPRLDRHLRKKAGLAVVPLNNALRNSEYQRQFVWKTCKETAPVCAANQVFRNKSQVIPQFQGNTFIHESEYKRNFKGLTPVKEPKLREYLKGNSSFEILSPEKKADEPLDLEVDMASEDSDQPIKKPAPWRHQRLGKVNSEYRAKFLSPAQYLYKAGAWTRVKESLSHQGSLNAMWYAEVKELREKAESYRKRVQGTHFSRDHLNQIMSDSNCCWDVSSVASSEGTISSNIQALDLAGDLTSHRTLQKHPPTKLEEKKVALAEQPLENTIRSLELPEAPTMARRKLAWDAAEGTQKEDTQEEPSGEEDGREARGKDKQVCAGELQKVDMQTSKADGPTEGSETSSVSSGKGGRLPTPRLRELGIQRTHHDLTTPAVGGAVLVSPAKAKPSALEQRRRPSSQDGLETLKKGITKKGKHRPLSLLTSPTAGMKTVDPLPLRQDCDANVLRVAEGTLPVLKNLDHQTNTPGQPSPCTLPYCHPSSRIQGRLRDPEFQHNIGKPRMNNTQLLPHGAFNDEDADRLSEISARSAVSSLQAFQTLARAQKRKENFWGKP

Protein

Nuclear protein MDM1: Mdm1

Gene

MDM1

Protein

Nuclear protein MDM1

Organism

Homo sapiens

Length

714 amino acids

Function

Microtubule-binding protein that negatively regulates centriole duplication. Binds to and stabilizes microtubules (PubMed:26337392).

Similarity

Belongs to the MDM1 family.

Mass

80.735 kDa

Sequence

MPVRFKGLSEYQRNFLWKKSYLSESCNSSVGRKYPWAGLRSDQLGITKEPSFISKRRVPYHDPQISKSLEWNGAISESNVVASPEPEAPETPKSQEAEQKDVTQERVHSLEASRVPKRTRSHSADSRAEGASDVENNEGVTNHTPVNENVELEHSTKVLSENVDNGLDRLLRKKAGLTVVPSYNALRNSEYQRQFVWKTSKETAPAFAANQVFHNKSQFVPPFKGNSVIHETEYKRNFKGLSPVKEPKLRNDLRENRNLETVSPERKSNKIDDRLKLEAEMELKDLHQPKRKLTPWKHQRLGKVNSEYRAKFLSPAQYLYKAGAWTHVKGNMPNQVKELREKAEFYRKRVQGTHFSRDHLNQILSDSNCCWDVSSTTSSEGTVSSNIRALDLAGDPTSHKTLQKCPSTEPEEKGNIVEEQPQKNTTEKLGVSAPTIPVRRRLAWDTENTSEDVQKQPGEKEEEDDNEEEGDRKTGKQAFMGEQEKLDVREKSKADKMKEGSDSSVSSEKGGRLPTPKLRELGGIQRTHHDLTTPAVGGAVLVSPSKMKPPAPEQRKRMTSQDCLETSKNDFTKKESRAVSLLTSPAAGIKTVDPLPLREDSEDNIHKFAEATLPVSKIPKYPTNPPGQLPSPPHVPSYWHPSRRIQGSLRDPEFQHNVGKARMNNLQLPQHEAFNDEDEDRLSEISARSAASSLRAFQTLARAKKRKENFWGKT

Protein

Nuclear protein MDM1: MDM1

Gene

Mdm1

Protein

Nuclear protein MDM1

Organism

Mus musculus

Length

708 amino acids

Function

Microtubule-binding protein that negatively regulates centriole duplication. Binds to and stabilizes microtubules.

Similarity

Belongs to the MDM1 family.

Mass

79.689 kDa

Sequence

MPVRFKGLSEYQRNFLWKKSYLSESYNPSVGQKYSWAGLRSDQLGITKEPGFISKRRVPYHDPQISKYLEWNGTVRKKDTLVPPEPQAFGTPKPQEAEQGEDANQEAVLSLEASRVPKRTRSHSADSRAEGVSDTVEKHQGVTRSHAPVSADVELRPSSKQPLSQSIDPRLDRHLRKKAGLAVVPTNNALRNSEYQRQFVWKTSKESAPVFASNQVFRNKSQIIPQFQGNTFTHETEYKRNFKGLTPVKEPKSREYLKGNSSLEMLTPVKKADEPLDLEVDMASEDSDQSVKKPASWRHQRLGKVNSEYRAKFLSPAQYFYKAGAWTRVKENLSNQVKELREKAESYRKRVQGTHFSRDHLNQIMSDSNCCWDVSSVTSSEGTVSSNIRALDLAGDLTNHRTPQKHPPTKLEERKVASGEQPLKNSTRRLEMPEPAASVRRKLAWDAEESTKEDTQEEPRAEEDGREERGQDKQTCAVELEKPDTQTPKADRLTEGSETSSVSSGKGGRLPTPRLRELGIQRTHHDLTTPAVGGAVLVSPSKVKPPGLEQRRRASSQDGLETLKKDITKKGKPRPMSLLTSPAAGMKTVDPLPLREDCEANVLRFADTLPVSKILDRQPSTPGQLPPCAPPYCHPSSRIQGRLRDPEFQHNMGKPRTNNLQLHPHDAFNDEDADRLSEISARSAVSSLRAFQTLARAQKRKENFWGKP

Protein

Nuclear protein MDM1: Mdm1

Gene

MDM1

Protein

Nuclear protein MDM1

Organism

Gallus gallus

Length

691 amino acids

Function

Microtubule-binding protein that negatively regulates centriole duplication. Binds to and stabilizes microtubules.

Similarity

Belongs to the MDM1 family.

Mass

77.35 kDa

Sequence

MPVRFRGLSEYKRNFRWKTPELCSPSQEQKSPWAGLRSDQLGITREPNFISKRRVPYHNPQISKSFEWTGDCDSDDPVETEALKTAESLAEHSNDVNQENTETPEGPRLPPKVRSHSSDSGVETALALAGNSMKKTPPVAPPNQKEAFVSPKKEAEKVNNGLHRVLQRKGGMNTPHLSTFPRNSEYQSQFVWKSPHEKSPILAAEEALYNTKREELIQKPAEDASKQEKSEQKHPKRKNKQHISQKPLSLHTHRGKMNTEYRSKFLSPAQYFYKDGAWSRIRSKVPNQASQNPLNSMWYMEVRELRARAKAYRQRIEGTHFSRYHLNQLLSDNNSLWDVSSNSSSEEGISNDIRALDLAGVSEKETAPRPKMLQQPGSREQSHQDDTEKKGLSDAPTVPVKRRLVWGEQEGTAEKDSQQLREEEEKENEQAAVVTQNLEKNNEGINEDNRIEGENTCLPNSPAAVSESSSVSSEPGGRLPTPKLRALGRAQRTHHDLTTPAVGGAVLVSPPKFKSSTSQQRMRSLGTDPSSVGQGAREASQRRSFRPGAKLKAVSLLTSPPAGLGTVDPLPLRQDQWHPNGVSGETVAINSAYQERSSTPPVLKSTKNRPMPCWSPSPRIQGTLKDPEFQHNGNVGNPKMGSFQLPLQERNYNNEDDRLSQISARSAASSSLASQILERAQKRKEDFWGKT

Protein

Nuclear protein MDM1: MDM1

Gene

mdm1

Protein

Nuclear protein MDM1

Organism

Danio rerio

Length

656 amino acids

Function

Microtubule-binding protein that negatively regulates centriole duplication. Binds to and stabilizes microtubules.

Similarity

Belongs to the MDM1 family.

Mass

74.293 kDa

Sequence

MPVRFKGISEYRSKYKGRTSRSRSDSPHRRMRLAGLRSDQSGITQEPQFISKRRVPFYPSQVSSSFRWEGRDHSQQQLEKSRSPAVSPVLRATSAERQVTPLAPRDPPEGTTAPSQPPQAEAAQTSTFAVQKQKQALNGINHALRMKAGLRSEHQRNGLNSEYQRQFMWKTPVAESPLLAAHQMLYSNNRAIPPFKTNPVIMESEYKRSFKGSPLPRPPRLRRDVEQYEVPEFLTESKTPEKSKRKKKKKERPHSRKSSPEQEVAYLQQQEVKSPHNLKDPSPKVMRKGKTEYRSNFHSPLQYSYKDGAWLKIKSAKEEVKELRERAEAYKKRAWGTHFSRQHLNQILSDQNWMWEPSSGTSSSSIESEACRSTSHIIEALDLARAGSVRESSSPGHSASVVVSRRSSSGEVGLPEEPTLPVQRKLAWDEEEQLGEREEIVQDRLTDKEGKTRNENGMERNERLNSLESESLSSAEEGSEASVNGGRLPTPKLKTMQTVQRTHHDRTTPSIDFNLHYIAKAANGSLPRSSPVAGLTTVDVLPMREDVWSDEEVTDYRSLKPPKPSRKQQSSQRHKANAAPPANRIQGTMRNAEFQHNGNLGIFRPELFVLPQSDSALSDNDDKMSQISSRSAASCSMASEVLGRAQRRKQEFWGKS

Protein

Nuclear protein MDM1: mdm1