MDAR4

Gene

MDAR4

Protein

Monodehydroascorbate reductase 4, peroxisomal

Organism

Arabidopsis thaliana

Length

488 amino acids

Function

Catalyzes the conversion of monodehydroascorbate to ascorbate, oxidizing NADH in the process (PubMed:16146528). Involved in the detoxification of H(2)O(2) that escapes the peroxisome and causes oxidative damage to oil bodies (PubMed:17449810).

Similarity

Belongs to the FAD-dependent oxidoreductase family.

Mass

53.526 kDa

Sequence

MGRAFVYVILGGGVAAGYAALEFTRRGVSDGELCIISEEPVAPYERPALSKGFLLPEAPARLPSFHTCVGANDEKLTPKWYKDHGIELVLGTRVKSVDVRRKTLLSSTGETISYKFLIIATGARALKLEEFGVEGSDAENVCYLRDLADANRLATVIQSSSNGNAVVIGGGYIGMECAASLVINKINVTMVFPEAHCMARLFTPKIASLYEDYYRAKGVKFIKGTVLTSFEFDSNKKVTAVNLKDGSHLPADLVVVGIGIRPNTSLFEGQLTIEKGGIKVNSRMQSSDSSVYAIGDVATFPVKLFGEMRRLEHVDSARKSARHAVSAIMDPIKTGDFDYLPFFYSRVFAFSWQFYGDPTGDVVHFGEYEDGKSFGAYWVKKGHLVGSFLEGGTKEEYETISKATQLKPAVTIDLEELEREGLGFAHTVVSQQKVPEVKDIPSAEMVKQSASVVMIKKPLYVWHAATGVVVAASVAAFAFWYGRRRRRW

Protein

Monodehydroascorbate reductase 4, peroxisomal: MDAR4

Gene

MDAR4

Protein

Monodehydroascorbate reductase 4, cytosolic

Organism

Oryza sativa subsp. japonica

Length

435 amino acids

Function

Catalyzes the conversion of monodehydroascorbate to ascorbate, oxidizing NADH in the process. Ascorbate is a major antioxidant against reactive oxygen species (ROS) and nitric oxide (NO).

Similarity

Belongs to the FAD-dependent oxidoreductase family.

Mass

46.685 kDa

Sequence

MAAAKHFTYVILGGGVAAGYAAREFAKQGVKPGELAIISKESVAPYERPALSKGYLFPQNAARLPGFHTCVGSGGERLLPEWYSEKGIELILSTEIVKADLASKTLTSSADATFTYDTLLIATGSSVIKLTDFGVQGAEANDILYLRDIEDADKLVAAMQAKKDGKAVIVGGGYIGLELSAALKTNNFDVTMVYPEPWCMPRLFTSGLAAFYEGYYANKGIHIIKGTVAVGFDADANGDVTAVKLKNGNVLEADIVIVGVGGRPLTHLFKGQVAEEKGGIKTDAFFETSVPGVYAIADVAAFPMKLYNEIRRVEHVDHARKSAEQAVKAIKAKEAGESVPEYDYLPYFYSRSFDLSWQFYGDNVGEDVLFGDNDPTAAKPKFGSYWIKDGKVVGVFLEGGSAEENQVIAKVARAQPPVADVEALKKEGLDFAAKV

Protein

Monodehydroascorbate reductase 4, cytosolic: MDAR4