Protein
Molybdenum cofactor sulfurase
Organism
Oryza sativa subsp. japonica
Function
Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
Similarity
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
Sequence
MEVSKEEFLRQFGGDYGYPGAPKGVDEMRAAEFKRLEGMAYLDHAGATLYSEAQMADVLKDLASNVYGNPHSQSDSSMAASDLVTAARHQVLKYFNASPREYKCIFTSGATAALKLVGECFPWSRESCYMYTMENHNSVLGIREYALSKGATVLAVDVEEGADLAKDNGSYSLYKISRRTNQRRSKDVLSHNCQNGSLSDISGNNWNIFAFPSECNFSGQKFSLSLVKLIKEGKIPLQQQGKWMVLIDAAKGCATEPPNLTVYPADFVVCSFYKIFGYPTGLGALIVKNEAANLLNKTYFSGGTVAASIADIDFVQKRKNIEQVLEDGTISFLNIASLRHGFKIIEMLTTSAIERHTTSLATYVRNKMLDLKHSNEINVCTIYGQQYSKVEGLKMGPTITFNLKREDGSWFGYREVEKLASLFGIHLRTGCFCNPGACAKYLGLSHSDLVSNFEAGHVCWDDNDIINGKPTGAVRISFGYMSTFEDAEKFLKFLQSSFVSLPVQFNNGYMLNLNSLNLIDNSSQKAVSDIHLKSIIIYPVKSCQGFSVKSWPLTTGGLMYDREWLLQGSGGEILTQKKVPELGSIRTLIDLELGKLFIESPTRRDKLQLSLLESLADLSEEVDVFGQRYEVQSYDDRVNTWFSEAIGRPCTLVRCSSSKYRSCTYTGLRDRPCRDTQSKLNFVNEGQLLLISEESISDLNSRLNSGKGDCKQKLPVDAMRFRPNLVISGSSPYSEDNWKKLRIGEACFTSMGGCNRCQMINLHQDSGQVLKSKEPLATLASYRRKKGKILFGILLNYEDIMEGENETIAGRWLQVGQQVYPSTE