MCPH1

Gene

MCPH1

Protein

Microcephalin

Organism

Macaca fascicularis

Length

842 amino acids

Function

Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex (By similarity).

Mass

93.53 kDa

Sequence

MAAPILKDVVAYVEVWSSNGTENYSKTFTTQLVDMGAKVSKTFNKQVTHVIFKDGYQSTWDKARKRGVKLVSVLWVEKCRTAGAHIDESLFPAANTNEHLPSLIKKKRKCMQPKDFNFKTPENDKRFQKKFEKMAKELQRQKTSLDDDVPILLFESNGSLTYSPTIKINSSHHSAMEKRLQEMKEKRENLSPTSSQMIQQSHDNPSNSLCEAPLNISHDTLCSDESIAGGLHSSFDDLCGNSECGNQERKLGGSINDTKSDMCISSLVLKTNNTHLSPSFAHLDKSSPQKFLSNLSKEEINLQRNIVGKIVTPDQKQAAGMSQETFEEKYRLSPTLSSTKGHLLIHSRPRSSSVKRKRVSYGFHSPPKEKCKRKRSIRRSIMPRLQLCRSEGSLQCMAGPALEALGCGESSYDDYFSPDNLKERNSENLPPKSQLPSNPAQFSCRSLSKKERTSIFEMSDFSCVGKKPRTVDITSFTAKTICSPQKTASGEGCATFSCVTSEESSAPEETLRYCRQAGPQQKEDAWPEGNGFSYTIEDPSLPKGHDGDLTPFEGILEEVKEAVGLKSTQDKGTTSKISNSSEGEAPSEHEPRSVVDCNVERSAEEKENLPGGYSGSVKNRPTRRDVLDGSCDSFKDLIKPHEELKKSGKGKKPTRTLVMTSMPSEKQNVVIQVVDKLKGFSIARDVCETTTHVLSGKPLRTLNVLLGIARGCWVLSYDWVLWSLESGQWISEEPFELSNHFPAAPLCRRECHLSAGPYRGTLFADQPVMFVSPASSPPVAKLCELVHLCGGRVSQVPRQASIVIGPYSGKKKATVKYLSEKWVLDSITQHKVCASENYLLPQ

Protein

Microcephalin: MCPH1

Gene

MCPH1

Protein

Microcephalin

Organism

Colobus guereza

Length

841 amino acids

Function

Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex (By similarity).

Mass

93.039 kDa

Sequence

MAAPILKDVVAYVEVWSSNGTENYSKTFTTQLVDMGAKVSKTFNKQVTHVIFKDGYQSTWDKAQKRGVKLVSVLWVEKCRTAGAHIDESLFPAANTNEHLPSLIKKKRKCMQPKDFNFKTPENDKRFQKKFEKMANELQRQKTSLDGDVPILLFESNGSLTYSPIIKINSSHHSAMEKRLQEMKEKRENLSPTSSQMIQQSHDNPSNSLCEAPLNISHDTLCSDESIAGLHSSFDDLCGYSGCGNQERKLGGSINDTKSAMCVSSLVLKTNHIHSSPSFAHLDKSSPQKFLSNLSKEEINLPRNIVGKIVTPDQKQAAGTSQETFEEKYRLSPTFSSTKGHLLIHSRPRSSSVKRKRVSYGFHSPPKEKCKRKRSIRRSIMPRLQLCSSEGSRQHMAGPALEALSCAESSYDDYFSPDNLKERNSENLPPESQLPSSPAQFSCRSLSKKERTSMFEMSDFSCIGKKTRTVDMTSFTAKTISSPQKTANGEGRATLSGVTSEESSAPEETLRCCRQAGPQQKEGACPEGNGFSYTIEDPALPKGHDGDLTPLEGILEEVKEAVGLKSTQDKGTTSKISNSSEGEASSEHEPRSVVDCNVERSAEEKENLLGGYSGSVKNRPTRHDVLDGSCDSFKDLIKPHEELKKSGKGKKPTRTLVMTSMPSEKQNIVIQVVDKLKGFSIAPDVCETTTHVLSGKPLRTLNVLLGIARGCWVLSYDWVLWSLESGHWISEESFELSNHFPAAPLCRRECHLSAGPYRGTLFADQPVMFVSPASSPPVAKLCELVHLCGGRVSQVPRQASIVIGPYSGKKKATVKYLSEKWVLDSITQHKVCASENYLLPQ

Protein

Microcephalin: MCPH1

Gene

MCPH1

Protein

Microcephalin

Organism

Hylobates lar

Length

840 amino acids

Function

Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex (By similarity).

Mass

92.887 kDa

Sequence

MAAHILKDVVAYVEVWSSNGTENYSKTFTTQLVDMGAKVSKTFNKQVTHVIFKDGYQSTWDKAQKRGVKLVSVLWVEKCRTAGAHIDESLFPAINTNEHLPSLIKKKRKCMQPKDFNFKTPENDKRFQKKFEKMAKELQRQKTSLDDDVPILLFESSGSLTYSPTIKINSSHHSAMEKRLQEMKEKRENLSPSSSQMIQQSHDNPSNSLCEAPLNISRDTLCSDESFAGGVHSSFDDLCGNSGCGNQERKLGGSINDIESDMCISSLVLKANNIHSSPSFTHLDKSSPQKFLSNLSKEEINLQRNIAGKIVTPDQKQAAGMSQETFEEKYRLSPTLSSTKGHLLIRSRPSSSSVKRQRVSHGSHSPSKGKSKRKRSIRRSIMPRLQLCRSEGSLQHVAGPALKALSCGESSYDDYFSPDNLKERNSENLPPTSQLPSSLAQFSCRSLSKKERTSIFEMSDFSCIGKKTRTVDITSFTAKTISSPQKTANGEGRATLSCVTSEESSAPGETLRCCRQAGKEDACPEGNGFSYTIEDPPFPKGHDGDLTPLEGSLEEVKEAVGLKSTQNKGTTSKISNSSEGEAQSEHEPCFIVDCNMETSTEEKENLPGGYGGSVKNRPTRHDLLDDSCDSFKDLIKPHEELKKSGRGKKPTRTLVMTSMPSEKQNVVIQVVDKLKGFSIAPDVCETTTHVLSGKPLRTLNVLLGIARGCWVLSYDWVLWSLELGHWISEEPFELSNHFPAAPLCRSECHLSAGPYRGTLFADQPVMFVSPASSPPVAKLCELVHLCGGRVSQVPRQASIVIGPYSGKKKATVKYLSEKWVLDSIIQHKVCASENYLLPQR

Protein

Microcephalin: MCPH1

Gene

MCPH1

Protein

Microcephalin

Organism

Pongo pygmaeus

Length

839 amino acids

Function

Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex (By similarity).

Mass

92.643 kDa

Sequence

MAAPILKDVVAYVEVWSSNGTENYSKTFTTQLVDMGAKVSKTFNKQVTHVIFKDGYQSTWDKAQKRGVKLVSVLWVEKCRTAGAHIDESLFPAANTNEHLPSLIKKKRKCMQPKDFNFKTPENDKRFQKKFEKMAKELQRQKTSLDGGVPILLFESNGSLIYSPTIEINSSHHSAMENRLQEMKEKRENLSPTSSQMIQQSHDNPSNSLCEAPLNISHDTLCSGESFAGGLHSSFDDLCGNSGCGNQERKLGGSINDIKSDMCISSLVLKANNTHSSPSFTHLDKSSPQKFLSNLSKEEINLQRNIAGKIVTPDQKQAAGMSQETFEEKYRLSPTLSSTKGHLLIHSRPRSSSVKRKRVSHGSHSPPKEKCKRKRSIRRSIMPRLQLCRSEGSLQHVAGPALQALSCGESSYDDYFSPDNLKERNSENLPPESQLPSSPAQFSCRSLSKKERTSIFEMSDFSCVGKKTRTVDIISFTAKTISSPQKTGNGEGLATLSCVTSEESSAPEEALRCCRQAGKEDACPEGNGFSYTIEDPVLPKGHDGDLTPLEGNLEEVKEAVGLKSTQNKGTTSKISNSSEGEAQSEHEPCFIGDCNMETSTEEKENLPGGYSGSVKNRPTRHDVLDDSCDGFKDLIKPHEELKKSERGKKPTRTLVMTSMPSEKQNVIIQVVDKLKGFSIAPDVCETTTHVLSGKPLRTLNVLLGIARGCWVLSYDWVLWSLELGHWISEEPFELSNHFPAAPLCRSECHLSAGPYRGTLFADQPVMFVSPASSPPVAKLCELVHLCGGRVSQVPRQASIVIGPYSGKKKATVKYLSEKWVLDSITQHKVCASENYLLSQ

Protein

Microcephalin: MCPH1

Gene

MCPH1

Protein

Microcephalin

Organism

Pan troglodytes

Length

835 amino acids

Function

Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex (By similarity).

Mass

92.584 kDa

Sequence

MAAPILKDVVAYVEVWSSNGTENYSKTFTTQLVEMGAKVSKTFNKQVTHVIFKDGYQSTWDKAQKRGVKLVSVLWVEKCRTAGAHIDESLFPAANTNEHLPSLIKKKRKCMQPKDFNFKTPENDKRFQKKFEKMAKELQRQKTNLDDDVPILLFESNGSLIYTPTIEINSSHHSAMEKRLQEMKEKRENLSPTSSQMIQQSHDNPSNSLCEAPLNISRDTLCSDECFAGGLHSSFDDLCGNSGCGNQERKLEGSINDIKSDVCISSLVLKANNIHSSPSFTHLDKSSPQKFLSNLSKEEINLQRNIAGKIVTPDQKQAAGVSQETFEEKYRLSPTLSSTKGHLLIHSRPRSSSVKRKRVSHGSHSPPKEKCKRKRSIRRSIMPRLQLCRSEGRLQHVAGPALEALSCGESSYDDYFSPDNLKERNSENLPPESQLPSSPAQFSCRSLSKKERTSIFEMSDFSCVGKKTRTVDITNFTAKTISSPQKTGNGEGRATSSCVTSAPEEALRCCGQAGKEDACPEGNGFSYTIEDPALPKGHDDDLTPLEGSLEEMKEAVDLKSTQNKGTTSKISNSSEGEAQSEHEPCFIVDCNMETSTEEKENLPGGYSGSVKNRPTRHDVLDDSCDGFKDLIKPHEELKKSGRGKKPTRTLVMTSMPSEKQNVVIQVVDKLKGFSIAPDVCETTTHVLSGKPLRTLNVLLGIARGCWVLSYDWVLWSLELGHWISEEPFELSHHFPAAPLCRSECHLSAGPYRGTLFADQPVMFVSPASSPPVAKLCELVHLCGGRVSQVPRQASIVIGPYSGKKKATVKYLSEKWVLDSITQHKVCASENYLLSQ

Protein

Microcephalin: MCPH1

Gene

MCPH1

Protein

Microcephalin

Organism

Gorilla gorilla gorilla

Length

835 amino acids

Function

Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex (By similarity).

Mass

92.591 kDa

Sequence

MAAPILKDVVAYVEVWSSNGTENYSKTFTTQLVDMGAKVSKTFNKQVTHVIFKDGYQSTWDKAQKRGVKLVSVLWVEKCRTAGAHIDESLFPAANTNEHLPSLIKKKRKCMQPKDFNFKTPENDKRFQKKFEKMAKELQRQKTSLDDDVPILLFESNGSLIYTPTIEINSSHHSAMEKRLQEMKEKRENLSPTSSQLIQQSHDNPSNSLCEAPLNISRDTLCSDEYFAGGLHSSFDDLCGNSGCGNQERKLEGSINDIKSDVCISSLVSKANNIHSSPSFTHLDKSSPQKFLSNLSKEEINLQRNIAGKIVTPDQKQAAGMSQETFEEKYRLSPTLSSIKGHLLIHSRPRSSSVKRKRVSHGSHSPPKEKCKRKRSIRRSIMPRLQLCRSEGRLQHVAGPALKALSCGESSYDDYFSPDNLKERNSENLPPESQLPSSPAQFSCRSLSKKERTSIFEMSDFSCVGKKTRTVDITNFTAKTISSPQKTGNGEGRATSSCVTSAPEEALRCCRQAGKEDGCPEGNGFSYTIEDPALPKGHDGDLTALEGSLEEMKEAVGLKSTQNRGTTSKISNSSEGEAQSEHEPCFIVDCNMETSTEEKENLPGGYSGSVKNRPTRHDVLDDSCDGFKDLIKPHEEMKKSGRGKKPTRTLVMTSMPSEKQNVVIQVVDKLKGFSIAPDVCETTTHVLSGKPLRTLNVLLGIARGCWVLSYDWVLWSLELGHWISEEPFELSHHFPAAPLCRSECHLSAGPYRGTLFADQPVMFVSPASSPPVAKLCELVHLCGGRVSQVPRQASIVIGPYSGKKKATVKYLSEKWVLDSITQHKVCASENYLLSQ

Protein

Microcephalin: MCPH1

Gene

MCPH1

Protein

Microcephalin

Organism

Homo sapiens

Length

835 amino acids

Function

Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex.

Mass

92.849 kDa

Sequence

MAAPILKDVVAYVEVWSSNGTENYSKTFTTQLVDMGAKVSKTFNKQVTHVIFKDGYQSTWDKAQKRGVKLVSVLWVEKCRTAGAHIDESLFPAANMNEHLSSLIKKKRKCMQPKDFNFKTPENDKRFQKKFEKMAKELQRQKTNLDDDVPILLFESNGSLIYTPTIEINSRHHSAMEKRLQEMKEKRENLSPTSSQMIQQSHDNPSNSLCEAPLNISRDTLCSDEYFAGGLHSSFDDLCGNSGCGNQERKLEGSINDIKSDVCISSLVLKANNIHSSPSFTHLDKSSPQKFLSNLSKEEINLQRNIAGKVVTPDQKQAAGMSQETFEEKYRLSPTLSSTKGHLLIHSRPRSSSVKRKRVSHGSHSPPKEKCKRKRSTRRSIMPRLQLCRSEDRLQHVAGPALEALSCGESSYDDYFSPDNLKERYSENLPPESQLPSSPAQLSCRSLSKKERTSIFEMSDFSCVGKKTRTVDITNFTAKTISSPRKTGNGEGRATSSCVTSAPEEALRCCRQAGKEDACPEGNGFSYTIEDPALPKGHDDDLTPLEGSLEEMKEAVGLKSTQNKGTTSKISNSSEGEAQSEHEPCFIVDCNMETSTEEKENLPGGYSGSVKNRPTRHDVLDDSCDGFKDLIKPHEELKKSGRGKKPTRTLVMTSMPSEKQNVVIQVVDKLKGFSIAPDVCETTTHVLSGKPLRTLNVLLGIARGCWVLSYDWVLWSLELGHWISEEPFELSHHFPAAPLCRSECHLSAGPYRGTLFADQPAMFVSPASSPPVAKLCELVHLCGGRVSQVPRQASIVIGPYSGKKKATVKYLSEKWVLDSITQHKVCAPENYLLSQ

Protein

Microcephalin: MCPH1

Gene

Mcph1

Protein

Microcephalin

Organism

Mus musculus

Length

822 amino acids

Function

Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex (By similarity).

Mass

90.373 kDa

Sequence

MEASGGVGGAFLKDVVAYVEVWSSKGTENYSRTFAKQLEDMGATVSKTLNKQVTHVIFKDGYQSTWDKAQKTGAKLVSVLWVEKCRMAGALVDESLFPAVNTDEHLPNLSRKKHKCMQPKDFILKTPENDKRLQKKFEKMAEELQRQKAALDDDVPVLLFESPRSLVYSSPVNVMKRRLQDMKEKRENLSPTSSQMLEQSQQNPCVSLFETSLNISHQPLSSDESFASGSHSSFGDSCGDQERKLGRSANEMTTVTCPSSPVLRASSFYGSASPNHLRQPRPQKAPDSPSKESINCQKDATGAVADSERKQAAGVSQGVPDEKLCLSPTMSIIEEHQVRLGPKNSSAKRKRAADLGSSPKGKLKKRYKRKSALAIQLFKSDQSPPSTIRLIPGTPDVEASSYEDYFSPDNLKERNSERLPPEAQQLASPSLFHCRGLSKWERRNMLEMCDFTCIGEKHRSISSISDLISKSASSLEKPVKEEVNTASTCLLLVETSANDSPGLCSQPGPQLRDDTGPEGSSHPDTLSSSAHHITPLKGNSTETRDPGDGKGSPKEGSTPPASASPEDEVHICNLSLGEDCNVEKSVEEKENIATGYSESVKNGPGRPDPSDSSCTGLVRPQQKPKKSEKEEKPTRTLVMTSMPSEKQTLIIQVVSTLKGFSFAPEVCETTTHVLVGKSARTLNVLMGIARGCWILSYEWVLLSLELGHWISEEPFELSETFPAAPICRLERHLSTQQYQGTLFANQPKMFIAPASSPPRAKLCELVLLCGGQVSPAPQLASLIIGPYKGKKKARIQYLSEKWVLDSITQHKICDFNNYQLLQ

Protein

Microcephalin: Mcph1