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MBTD1

Gene
mbtd1
Protein
MBT domain-containing protein 1
Organism
Xenopus tropicalis
Length
651 amino acids
Function
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Specifically binds to monomethylated and dimethylated 'Lys-20' on histone H4 (By similarity).
Mass
72.91 kDa
Sequence
MEKTKDLADLSSLSERKRRDSFGMFDGYDSCSEDTSSSSSSDESEEEVAPLPSSLPIIKNNGQVYTYPDGKSGMATCEMCGMVGVRDAFYSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLQKKPLVAKLAAYAQYKATLKNQSVNKAPVTVEGFSWGNYITSNNTAAAPVTCFRHAPMGNCWGDIAEGVRVEVPNTDSNLPTKVFWISGIVKLAGFNALLRYEGFENDSSLDFWCNICGPDVHPVGWCATSGKPLVPPQTIQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSESMQYPFKPSMRVEVVDKTHLCRTRVAVVDSVIGGRLRLVYEESEDKTDDFWCHMYSPLIHPIGWSRSIGHRFKRTDILKKQESNYDAPSHLFTKVKDIEQGSEWFKEGMKLEAIDPLNLSAICVATIRKVLADGYLMIGIDGSEAADGSDWFCYHASSPSIFPVGFCEINKIELTPPRGYTKLPFKWFDYLRETGSIAAPVKLFNKEVPNHGFRVGMKLEAVDLMEPRLVCVATVTRIIHRLLRIHFDGWEDEYDQWVDCESSDLYPVGWCQLTGYQLQPPAPQSNKDSQSNISKQKKKSKSQPYKGHKKITALQLKDEMLDGDDYTFLQGASDQESNGSGSYYIKQEP

Gene
Mbtd1
Protein
MBT domain-containing protein 1
Organism
Mus musculus
Length
631 amino acids
Function
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Specifically binds to monomethylated and dimethylated 'Lys-20' on histone H4 (By similarity).
Mass
70.669 kDa
Sequence
MFDGYDSCSEDTSSSSSSEESEEEVAPLPSNLPIIKNNGQVYTYPDGKSGMATCEMCGMVGVRDAFYSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLQKQPLVAKLAAYAQYQATLQNQAKTKAGNSAISVEGFSWGNYINSNSFIAAPVACFKHAPMGTCWGDISENVRIEVPNTDCSLPTKVFWIAGIIKLAGYNALLRYEGFENDSSLDFWCNICGSDIHPVGWCAASGKPLVPPRTVQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSESMQYPFKPCMRVEVVDKRHLCRTRVAVVESVIGGRLRLVYEESEDRTDDFWCHMHSPLIHHIGWSRSIGHRFKRSDITKKQDGHFDTPPHLFAKVKEVDQSGEWFKEGMKLEAIDPLNLSTICVATIRKVLADGFLMIGIDGSEAADGSDWFCYHATSPSIFPVGFCEINMIELTPPRGYTKLPFKWFDYLRETGSIAAPVKLFNKDVPNHGFRVGMKLEAVDLMEPRLICVATVTRIIHRLLRIHFDGWEEEYDQWVDCESPDLYPVGWCQLTGYQLQPPASQSSRESQSASSKQKKKAKSQQYKGHKKMTTSQLKEELLDGEDYSFLHGASDQESNGSATVYIKQEP

Gene
MBTD1
Protein
MBT domain-containing protein 1
Organism
Homo sapiens
Length
628 amino acids
Function
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity). Specifically binds to monomethylated and dimethylated 'Lys-20' on histone H4.
Mass
70.547 kDa
Sequence
MFDGYDSCSEDTSSSSSSEESEEEVAPLPSNLPIIKNNGQVYTYPDGKSGMATCEMCGMVGVRDAFYSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLQKQPLVAKLAAYAQYQATLQNQAKTKAAVSMEGFSWGNYINSNSFIAAPVTCFKHAPMGTCWGDISENVRVEVPNTDCSLPTKVFWIAGIVKLAGYNALLRYEGFENDSGLDFWCNICGSDIHPVGWCAASGKPLVPPRTIQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSESMQYPFKPCMRVEVVDKRHLCRTRVAVVESVIGGRLRLVYEESEDRTDDFWCHMHSPLIHHIGWSRSIGHRFKRSDITKKQDGHFDTPPHLFAKVKEVDQSGEWFKEGMKLEAIDPLNLSTICVATIRKVLADGFLMIGIDGSEAADGSDWFCYHATSPSIFPVGFCEINMIELTPPRGYTKLPFKWFDYLRETGSIAAPVKLFNKDVPNHGFRVGMKLEAVDLMEPRLICVATVTRIIHRLLRIHFDGWEEEYDQWVDCESPDLYPVGWCQLTGYQLQPPASQSSRENQSASSKQKKKAKSQQYKGHKKMTTLQLKEELLDGEDYNFLQGASDQESNGSANFYIKQEP

Gene
mbtd1
Protein
MBT domain-containing protein 1
Organism
Xenopus laevis
Length
621 amino acids
Function
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Specifically binds to monomethylated and dimethylated 'Lys-20' on histone H4 (By similarity).
Mass
69.812 kDa
Sequence
MEKTKDPADRSSRSERKRRDSFGMFDGYDSCSEDTSSSSSSDESEEEVAPLPSSLPIIKNNGQVYTYPDGKSGMATCEMCGMVGVRDAFYSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLQKKPLVAKLAAYAQYKATLKNQSVNKAPVTVEGFSWGNYITSNNVIAAPVTCFRHAPMGNCWGDIAEGVRIEVPNTDSNLPTKVFWISGIVKLAGYNALLRYEGFENDSSLDFWCNICGPDIHPVGWCATSGKPLVPPQSIQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSENMQYPFKPSMRVEVVDKTHLCRTRVAVVESVIGGRLRLVYEESEDKTDDFWCHMYSPLIHPIGWSRSIGHRFKRTDILKKQESNYDAPSHLFIKVKDVEQGSEWFKEGMKLEAIDPLNLSAICVATIRKVLAEGYLMIGIDGSEAADGSDWFCYHASSPSIFPVGFCEINKIELTPPRGYTKLPFKWFDYLRETGSIAAPVKLFNKDVPNHGFRVGMKLEAVDLMEPRLVCVATVTRIIHRLLRIHFDGWEDEYDQWVDCESPDLYPVGWCQLTGYQLQPPAPQSNKDGQSNVSKQKKKSKSQPYKGHKKNFRKPGNRP