mapkbp1

Mitogen-activated protein kinase-binding protein 1

1580 amino acids

Involved in JNK signaling pathway.

174.157 kDa

MATIESGTTITSRLKNLLRSPSIKLRRHKAGTKKEDLSSKVTLEKVLGITVSAGRGLSCDPKTGLVAYPAGCVVVLLNPRKNKQQHILNSSRKTITALAFSPDGKFLVTGESGHMPAVRVWDVAERTQVAELQEHKYGVACVAFSPTSKYIVSVGYQHDMIVNVWSWKKNVVVAANKVSSKVTAVSFSEDSSYFVTAGNRHVKFWYLDEAKSSKVNSTIPLLGRSGLLGELRNNFFTDVACGKSKKSSSTFCITSSGLLCEFNDQRLLDKWVELRTTVANCILVNHDYIFCGCADGTVRIFNPNNLHFLSTMPKPHCLGVDIATVTEASRLFSSAADAKYPDTIAMTFDPTNQWLSCVYNDHSLYVWDVKDLKKVGKVYSSLYHSSCVWSIEIYPEIKDSNQACLPPNSFITCSSDSTIRLWNMETSNIHGTALHRNILSNDLMKIILIDDNTQALLDTEYNSAGLGDKADHQALDTKVGIRSVCVSPNGQHLASGDRTGTLRVHELQSMTELLKVEAHDSEILCLEYSKPDTGLNLLASASRDRLIHVLDASKDYSLQQTLDDHSSSITAVKFAANDGKVQMISCGADKSIYFRTADKVGDAAVHFTRTHHIVRKTTLYDMDVDPSLKYAAIGCQDRNIRIFNISSGKQKKLYKGSQSEDGTLIKVQTDPSGLYIATSCSDKNLSIFDFYSGECVATMFGHSEVVTGMKFTNDCKHLISVSGDSCVFIWRLSSEMTINMRQRLAEVRQRGKQVEMSATHKTQNARRETIAVMSTAPVMSSDSDKEGVEDGSDEDTAGSDKASSASSSFGRSNSYWEMARGTNTSSERSNCLSKMPRQRVRWSQPAGNIEMTVKSMLDLRQLDSFAPCDDIIGFQPSEGLGTEFVVADNSSIQAPFGPIGSRSRPRVIRLMSCEETMFKQDVETPEGKECTIFPEMEEDESLERCGGFEVKGLPLRSYHDNVCQEKHSPDSACSVDYSSRLSSPEHPNEDSESTEPLSVDANSSDLEEQVEAEDLEPNSPVMDGEIPQTPDQEKFLKQHFGNLSAGNIPGGPLLTSERNDFSSISSRFLAMAAPSKNQPVESLMFDSEFSPALFQPSMEHPALINRTESQPKSAITTDHDFTSPQKLNYFQRKRKHLQEYEHIGKGGPFSSVMQIRKTQSVHDLVNEGNKTTANGGIVKMRSQVQTAAEREEKAIRRRTLPSTLIKVENLASGTPHSKDGKLAKGRSYMNPTTSSMAKISRSMSVGENLNIEENQDASLSFDGKGNCEPEIGAIPSFVETEKNRQTAKETVIIKPHLQPVANCSSTKTFQTKNRAHLTLDIAKPLPDRPLLSFNKGKGALEMESPRSPASSCKVKSSFSEFTCRNDNQASGALEKTSPSEDYGCSKSKENDVKANSKPNVYQERVELFSDMLKPIHRGRASTIGHTPDHHSGLCPEVEPIRPRSPSLNAAPTHNSASSVSFEQCELIASELQDSLQKALSLYRSVTTADPSANMERCKIAGLLTETFGMVKRELDFLKEGNSSPGTAMTPQDETGSDFTAPNLHEEHGTRRLGDDKTLALLQQYSELLLQAVEKRMDKKL

MAPKBP1

Mitogen-activated protein kinase-binding protein 1

1514 amino acids

Negative regulator of NOD2 function. It down-regulates NOD2-induced processes such as activation of NF-kappa-B signaling, IL8 secretion and antibacterial response (PubMed:22700971). Involved in JNK signaling pathway (By similarity).

163.818 kDa

MAVEGSTITSRIKNLLRSPSIKLRRSKAGNRREDLSSKVTLEKVLGITVSGGRGLACDPRSGLVAYPAGCVVVLFNPRKHKQHHILNSSRKTITALAFSPDGKYLVTGESGHMPAVRVWDVAEHSQVAELQEHKYGVACVAFSPSAKYIVSVGYQHDMIVNVWAWKKNIVVASNKVSSRVTAVSFSEDCSYFVTAGNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNLFTDVACGRGKKADSTFCITSSGLLCEFSDRRLLDKWVELRNIDSFTTTVAHCISVSQDYIFCGCADGTVRLFNPSNLHFLSTLPRPHALGTDIASVTEASRLFSGVANARYPDTIALTFDPTNQWLSCVYNDHSIYVWDVRDPKKVGKVYSALYHSSCVWSVEVYPEVKDSNQACLPPSSFITCSSDNTIRLWNTESSGVHGSTLHRNILSSDLIKIIYVDGNTQALLDTELPGGDKADASLLDPRVGIRSVCVSPNGQHLASGDRMGTLRVHELQSLSEMLKVEAHDSEILCLEYSKPDTGLKLLASASRDRLIHVLDAGREYSLQQTLDEHSSSITAVKFAASDGQVRMISCGADKSIYFRTAQKSGDGVQFTRTHHVVRKTTLYDMDVEPSWKYTAIGCQDRNIRIFNISSGKQKKLFKGSQGEDGTLIKVQTDPSGIYIATSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSCIFVWRLSSEMTISMRQRLAELRQRQRGGKQQGPSSPQRASGPNRHQAPSMLSPGPALSSDSDKEGEDEGTEEELPALPVLAKSTKKALASVPSPALPRSLSHWEMSRAQESVGFLDPAPAANPGPRRRGRWVQPGVELSVRSMLDLRQLETLAPSLQDPSQDSLAIIPSGPRKHGQEALETSLTSQNEKPPRPQASQPCSYPHIIRLLSQEEGVFAQDLEPAPIEDGIVYPEPSDNPTMDTSEFQVQAPARGTLGRVYPGSRSSEKHSPDSACSVDYSSSCLSSPEHPTEDSESTEPLSVDGISSDLEEPAEGDEEEEEEEGGMGPYGLQEGSPQTPDQEQFLKQHFETLASGAAPGAPVQVPERSESRSISSRFLLQVQTRPLREPSPSSSSLALMSRPAQVPQASGEQPRGNGANPPGAPPEVEPSSGNPSPQQAASVLLPRCRLNPDSSWAPKRVATASPFSGLQKAQSVHSLVPQERHEASLQAPSPGALLSREIEAQDGLGSLPPADGRPSRPHSYQNPTTSSMAKISRSISVGENLGLVAEPQAHAPIRVSPLSKLALPSRAHLVLDIPKPLPDRPTLAAFSPVTKGRAPGEAEKPGFPVGLGKAHSTTERWACLGEGTTPKPRTECQAHPGPSSPCAQQLPVSSLFQGPENLQPPPPEKTPNPMECTKPGAALSQDSEPAVSLEQCEQLVAELRGSVRQAVRLYHSVAGCKMPSAEQSRIAQLLRDTFSSVRQELEAVAGAVLSSPGSSPGAVGAEQTQALLEQYSELLLRAVERRMERKL

Mapkbp1

Mitogen-activated protein kinase-binding protein 1

1503 amino acids

Negative regulator of NOD2 function. It down-regulates NOD2-induced processes such as activation of NF-kappa-B signaling, IL8 secretion and antibacterial response (By similarity). Involved in JNK signaling pathway (PubMed:10471813).

162.892 kDa

MMAGEGSTITSRIKNLLRSPSIKLRRSKAGNRREDLSSKVTLEKVLGVTVSGGRGLACDPRSGLVAYSAGCVVVLFNPRKHKQHHILNSSRKTITALAFSPDGKYLVTGESGHMPAVRVWDVAERSQVAELQEHKYGVACVAFSPSAKYIVSVGYQHDMIVNVWAWKKNIVVASNKVSSRVTAVSFSEDCSYFVTAGNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNLFTDVACGRGEKADSTFCITSSGLLCEFSDRRLLDKWVELRTTVAHCISVTQEYIFCGCADGTVRLFNPSNLHFLSTLPRPHALGTDIASITEASRLFSGGVNARYPDTIALTFDPTNQWLSCVYNDHSIYVWDVRDPKKVGKVYSALYHSSCVWSVEVYPEIKDSHQACLPPSSFITCSSDNTIRLWNTESSGVHGSTLHRNILSNDLIKIIYVDGNTQALLDTELPGGDKADGSLMDPRVGIRSVCISPNGQHLASGDRMGTLRIHELQSLSEMLKVEAHDSEILCLEYSKPDTGLKLLASASRDRLIHVLDAGREYSLQQTLDEHSSSITAVKFAASDGQVRMISCGADKSIYFRTAQKSGEGVQFTRTHHVVRKTTLYDMDVEPSWKYTAIGCQDRNIRIFNISSGKQKKLFKGSQGEDGTLIKVQTDPSGIYIATSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSCIFVWRLSSEMTISMRQRLAELRQRQRGIKQQGPTSPQRASGAKQHHAPVVPPSGPALSSDSDKEGEDEGTEEEELPALPILSKSTKKELASGSSPALLRSLSHWEMSRAQETMEYLDPAPVANTGPKRRGRWAQPGVELSVRSMLDLRQIETLAPSPRGPSQDSLAVSPAGPGKHGPQGPELSCVSQNERAPRLQTSQPCSCPHIIQLLSQEEGVFAQDLEPAPIEDGIVYPEPSDSPTMDTSAFQVQAPTGGSLGRMYPGSRGSEKHSPDSACSVDYSSSRLSSPEHPNEDSESTEPLSVDGISSDLEEPAEGDEDEEEEGGTGLCGLQEGGPHTPDQEQFLKQHFETLANGTAPGGPARVLERTESQSISSRFLLQVQTSPLREPSLSSSGLALTSRPDQVSQVSGEQLKGSGATPPGAPPEMEPSSGNSGPKQVAPVLLTRRHNNLDNSWASKKMAATRPLAGLQKAQSVHSLVPQDEVPSSRPLLFQEAETQGSLGSLPQAGGCSSQPHSYQNHTTSSMAKLARSISVGENPGLATEPQAPVPIRISPFNKLALPSRAHLVLDIPKPLPDRPTLTTFSPVSKGLAHNETEQSGPLVSLGKAHTTVEKHSCLGEGTTHKSRTECQAYPGPNHPCAQQLPVNNLLQGPESLQPLSPEKTRNPVESSRPGVALSQDSELALSLQQCEQLVAELQGNVRQAVELYRAVTSYKTPSAEQSHITRLLRDTFSSVRQELEVLAGAVLSSPGGSPGAVGAEQTQALLEQYSELLLRAVERRMERRL