MAP4K5

Gene

Map4k5

Protein

Mitogen-activated protein kinase kinase kinase kinase 5

Organism

Mus musculus

Length

847 amino acids

Function

May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway (By similarity).

Similarity

Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

Mass

95.045 kDa

Sequence

MEAPLRPAADILRRNPQHDYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFSLIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSEMQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPYWMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVGQPGLSRALAVELLDKVSNPDNHAPYSEGDEDDLEPHAIIRHTIRSTNRNSRAERTASEINFDKLQFEPPLRKETEARDEMGLSSEPNFILHWNPFVDGANTGRSTSKRAIPPPLPPKPRVNTYPEDSLPDEEKSSTIKRCPDLEARAPQVLRRQSSPSCVPVAETSSSIGNGDGISKLISENTEGSAQAPQLPRKKDKRDFPKPTINGLPPTPKVLMGACFSKVFDGCPLKINCATSWIHPDTKDQYIIFGTEDGIYTLNLNELHEATMEQLFPRKCTWLYVINNTLMSLSEGKTFQLYSHNLIALFEQAKKPGLAAHIQTHRFPDRILPRKFALTTKIPDTKGCHKCCIVRNPYTGHKYLCGALQSGIVLLQWYEPMQKFMLIKHFDFPLPSPLNVFEMLVIPEQEYPMVCVAISKGSDSSQVVQFETINLNSASSWFTEIGAGSQQLDSIHVTQLERDTVLVCLDKFVKIVNLQGKLKSSKKLASELSFDFRIESVVCLQDSVLAFWKHGMQGKSFKSDEVTQEISDETRVFRLLGSDRVVVLESRPTENPAAHSNLYILAGHENSY

Protein

Mitogen-activated protein kinase kinase kinase kinase 5: Map4k5

Gene

MAP4K5

Protein

Mitogen-activated protein kinase kinase kinase kinase 5

Organism

Homo sapiens

Length

846 amino acids

Function

May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

Similarity

Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

Mass

95.024 kDa

Sequence

MEAPLRPAADILRRNPQQDYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFSLIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSELQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPYWMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVAQPGLSRALAVELLDKVNNPDNHAHYTEADDDDFEPHAIIRHTIRSTNRNARAERTASEINFDKLQFEPPLRKETEARDEMGLSSDPNFMLQWNPFVDGANTGKSTSKRAIPPPLPPKPRISSYPEDNFPDEEKASTIKHCPDSESRAPQILRRQSSPSCGPVAETSSIGNGDGISKLMSENTEGSAQAPQLPRKKDKRDFPKPAINGLPPTPKVLMGACFSKVFDGCPLKINCATSWIHPDTKDQYIIFGTEDGIYTLNLNELHEATMEQLFPRKCTWLYVINNTLMSLSVGKTFQLYSHNLIALFEHAKKPGLAAHIQTHRFPDRILPRKFALTTKIPDTKGCHKCCIVRNPYTGHKYLCGALQSGIVLLQWYEPMQKFMLIKHFDFPLPSPLNVFEMLVIPEQEYPMVCVAISKGTESNQVVQFETINLNSASSWFTEIGAGSQQLDSIHVTQLERDTVLVCLDKFVKIVNLQGKLKSSKKLASELSFDFRIESVVCLQDSVLAFWKHGMQGKSFKSDEVTQEISDETRVFRLLGSDRVVVLESRPTENPTAHSNLYILAGHENSY

Protein

Mitogen-activated protein kinase kinase kinase kinase 5: MAP4K5