Protein
8-amino-7-oxononanoate synthase
Organism
Methylobacterium sp. (strain 4-46)
Function
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
Similarity
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Sequence
MPVPPTLSLDAFAAAKLAGLDAAGLRRRLVPTARTGGARAERDGRAVVSFSCNDYLGLATHPEVVAAAHAALDRYGAGSGGSRLVTGSHPILAELEAALAARKGHEAALVFGSGYLANLGVTPALVGAGDLILIDELGHSCMWAGTRLAGARALPFRHNDLGHLEDLLARERARARRALILTERVFSMDGDRAPVAEILGLARAFDAWTLVDDAHGLGVVGPDATAPLEMGTLSKALGSYGGYLCASRPVIDLLTSRARSFVYTTGLPPASAAAALAALRLIEAEPARAARPLALARRFTARLGLPEAQSAVVPVLVGEAEAALALSRALEARGFLVVAIRPPTVPPGTARLRVAFSAAHEEAEVDALAQALLDLGAAA