Organism
Murid herpesvirus 1 (strain K181)
Function
Plays a role in the inhibition of host type I interferon production within the host nucleus. Targets specifically the NF-kappa-B-mediated interferon-beta transcription.
Sequence
MAAPTEEDPRRDTSLMINERCNFPHNMLSEENINFIQDAVCNGDLGAVAALNSGLPMAPYMLEALLAVRVKHRLTKVRQTLEPVICYTISVAHLINGTRILRSATAKHATAWGPNDKHRAESGLRRIYRALNLEDNPFDLVEAVGDLDLSQGAYEGYVRHIYSLMKSLGHDVGHLSRSLDYSTMTVFNYLYESPLFTSQEAVTMYSRNLAGITKMSREPFETLSVVHRSKEPPEILNDMLFLLSVGRMIVLHQESLRALRKNLILTASALCSILYTAYTQVPETKSLFREVAHEAHALLSSRSPDTPNFRPFVACMLQFIKQIIAADVYTCPRYLTNQILAVTARMHGLEGAAMGHDDDLDIEVDPGNPYSAKYRMNNPYNDQNIFKCPRSLVHYVGDALFKKTMTQELLVSCTDQEATYQTYELPSVSELVGEGVAKRAHLTPDQLSHYLSVVSTPVEVVTDDIEDGEQEEDLFADVSVAPASPVRPIRGGGQRMANMRGARPYSTVQRGRRRHESEV