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M1425_1450

Gene
M1425_1450
Protein
Protein archease
Organism
Sulfolobus islandicus (strain M.14.25 / Kamchatka #1)
Length
139 amino acids
Function
Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).
Similarity
Belongs to the archease family.
Mass
16.328 kDa
Sequence
MRSFEFFEHTADVGIRAYGKSLEEAFSNAALGVFEVITDTSKVKPIEYREIYLNGYDLENLLYKWIEELLYYYDSELMVFSKFDLMIDQDSMTLEGKAWGEKFNGKIHERRTVVKAMTYHQLSIEKTENGYVITFVVDI