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LY96

Gene
LY96
Protein
Lymphocyte antigen 96
Organism
Bos taurus
Length
160 amino acids
Function
Binds bacterial lipopolysaccharide (LPS). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria (By similarity). Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS.
Mass
18.484 kDa
Sequence
MFPFMLFSTLFSSIFTEPREKMWICNSSDASLWYNYCDDMKFPISVKVEPCVTIKGTKGKLHLYYIARRDIQKLYLNLHISIKSMTLPMRKEVICREYGGDYSFCGALKGETVNTTIPFSFQGIRFSPGQYHCVVEAISGNSEEMLFCLNFTIIHYSSLN

Gene
LY96
Protein
Lymphocyte antigen 96
Organism
Cricetulus griseus
Length
160 amino acids
Function
Binds bacterial lipopolysaccharide (LPS). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS.
Mass
18.357 kDa
Sequence
MLPFILFSTLLPLIFTESEQQLWFCNSSDATFSYSYCDSMKFPFSITAEPCITLKGTNGFLHIKFIPRRDLKKLYFNLSINVNSIEVPTRKEIICHGYDDNYSFCKALKGETVNTVVPFSFKGILFPKGQYRCVAEAIVGDNEEKLFCLNFTIIHHPNVN

Gene
LY96
Protein
Lymphocyte antigen 96
Organism
Homo sapiens
Length
160 amino acids
Function
Binds bacterial lipopolysaccharide (LPS) (PubMed:17803912, PubMed:17569869). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria (PubMed:11160242, PubMed:11593030). Enhances TLR4-dependent activation of NF-kappa-B (PubMed:10359581). Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS (PubMed:10359581).
Mass
18.546 kDa
Sequence
MLPFLFFSTLFSSIFTEAQKQYWVCNSSDASISYTYCDKMQYPISINVNPCIELKRSKGLLHIFYIPRRDLKQLYFNLYITVNTMNLPKRKEVICRGSDDDYSFCRALKGETVNTTISFSFKGIKFSKGKYKCVVEAISGSPEEMLFCLEFVILHQPNSN

Gene
Ly96
Protein
Lymphocyte antigen 96
Organism
Mus musculus
Length
160 amino acids
Function
Binds bacterial lipopolysaccharide (LPS) (PubMed:22532668). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS (PubMed:10725698).
Mass
18.394 kDa
Sequence
MLPFILFSTLLSPILTESEKQQWFCNSSDAIISYSYCDHLKFPISISSEPCIRLRGTNGFVHVEFIPRGNLKYLYFNLFISVNSIELPKRKEVLCHGHDDDYSFCRALKGETVNTSIPFSFEGILFPKGHYRCVAEAIAGDTEEKLFCLNFTIIHRRDVN