Lrrc6

Protein tilB homolog

473 amino acids

May play a role in dynein arm assembly, hence essential for proper axoneme building for cilia motility.

Belongs to the tilB family.

55.049 kDa

MGRITEDLIRRNAEHNDCVIFSLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEYLNLALNNIERIENLEGCEWLTKLDLTVNFIGELSSVKTLTHNIHLKELFLMGNPCADFDGYRQFVVVTLQQLKWLDGKEIERSERIQALQNYTSVEQQIREQEKAYCLRRAKEKEEAQRKLEEENESEDKKKSSTGFDGHWYTDIHTACPSATENQDYPQVPETQEEQHNTKESDDIEDDLAFWNKPSLFTPESRLETLRHMEKQRKAQDKLSEKKKKAKPPRTLITEDGKVLNVNEAKLDFSLKDDEKHNQIILDLAVYRYMDTSLIEVDVQPTYVRVMVKGKPFQLALSTEVQPDRSSAKRSQTTGHLLICMPKVGEMITGGQRTPTSVKTTSTSSREQTNPRKKQIERLEVDPSKHSCPDVSTIVQEKRHRPKRMESQPRDEPSEEDPDFEDNPEVPPLI

LRRC6

Protein tilB homolog

472 amino acids

May play a role in dynein arm assembly, hence essential for proper axoneme building for cilia motility.

Belongs to the tilB family.

54.542 kDa

MGRITEDLIRRNAEHNDCVIFSLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEYLNLALNNIEKIENLEGCEGLTKLDLTVNFIGELSSVKTLQGNIHLKELFLMGNPCADFDGYRQFVVATLQQLKWLDGKEIERSERIQALQNLPVVEQRIREQEKAYCLKRAKDKEEAQRKLEEEESKGEMGRSHTGSGGHWHADLSATLPSFEESKDYIQAPEIEEGQCKGKEFDDREDDLEFWNKPSLYTPESRLETLRHMEKQRRDQERLSEKKKKVKPPRMLVTEDGRALNVNEPKLDFTLKDDEKRNQIVLDLAVYRYMDTSLIDVDVQPTYVRVMVKGKPFQLILPAEVKPDSSFAKRSQTTGHLVVCMPKVGEVIIGCQRTSKPVKSTPDSSKEQTSKSQQMERLEVDPSKRSIPDVANIVQEKKHMPRRVCAEPKIIPSEEDPDFEDNPEVPPLI

lrrc6

Protein tilB homolog

470 amino acids

May play a crucial role in regulating cilia motility in pronephric tubules, cloaca and neural tube. May be required for establishing left-right asymmetry of the body plan; controls cell fate and convergent extension (CE) movements during gastrulation, respectively, via the Wnt and the planar cell polarity (PCP) signaling pathways. Required for the proper development of renal glomeruli and tubules (By similarity).

Belongs to the tilB family.

54.621 kDa

MVRVSEDLIRRRAEHNNCEIFSLEEISLHQQDLERIEYIDKWCRELKILYLQNNLIGKIENVSKLKKLEYLNLALNNIEKIENLEGCESLQKLDLTVNFVGDLSSINSLQENRQLREFYLVGNPCAEYEGYRQYVVATLPQLKWLDGKEIERSERIQAAQDYPQVQGKIKEQEEAYLRKRAAEREKATNNLQQKQKEGRKAQEKKPGFDRRWYTDINNTIPDPVEKTDTVAQLNVDETALRNDDEEEEKEFWNQPSQYTPESRLETHRYLEEKRKSKENRSEEELKKKPPRTLITAEGRVLNVNESKLDFSLVDDEENNQFVLDLAIYRHLDTSLLDVDVQPGYIKVLVKEKPFQLVLPAEVKPDSSAAKRSQTTGHLVVTMPKATEMIQTKRAKSPAIAERTCKNPQKCLKTHEKLEVDPKARSIPDVANIVQEKKTWAQGPLRLHRNSARDTADSEDFIDNAEVPPLV

LRRC6

Protein tilB homolog

466 amino acids

May play a role in dynein arm assembly, hence essential for proper axoneme building for cilia motility.

Belongs to the tilB family.

54.255 kDa

MGWITEDLIRRNAEHNDCVIFSLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEYLNLALNNIEKIENLEGCEELAKLDLTVNFIGELSSIKNLQHNIHLKELFLMGNPCASFDHYREFVVATLPQLKWLDGKEIEPSERIKALQDYSVIEPQIREQEKDHCLKRAKLKEEAQRKHQEEDKNEDKRSNAGFDGRWYTDINATLSSLESKDHLQAPDTEEHNTKKLDNSEDDLEFWNKPCLFTPESRLETLRHMEKQRKKQEKLSEKKKKVKPPRTLITEDGKALNVNEPKIDFSLKDNEKQIILDLAVYRYMDTSLIDVDVQPTYVRVMIKGKPFQLVLPAEVKPDSSSAKRSQTTGHLVICMPKVGEVITGGQRAFKSMKTTSDRSREQTNTRSKHMEKLEVDPSKHSFPDVTNIVQEKKHTPRRRPEPKIIPSEEDPTFEDNPEVPPLI

lrrc6

Protein tilB homolog

440 amino acids

Plays a crucial role in regulating cilia motility in pronephric tubules, cloaca and neural tube. Required for establishing left-right asymmetry of the body plan; controls cell fate and convergent extension (CE) movements during gastrulation, respectively, via the Wnt and the planar cell polarity (PCP) signaling pathways. Required for the proper development of renal glomeruli and tubules.

Belongs to the tilB family.

50.677 kDa

MVRISEDLIRRRAEHNNGEIFSLEELSLHQQDIQRIEHIHKWCRDLKILYLQNNLIPKIENVGRLKKLEYLNLALNNIEVIENLEGCESLQKLDLTVNFVGRLSSVETLKHNLHLKELYLVGNPCAEYQGYRQYVVATVPQLQSLDGKEISRAERIQALQELDAVRTRVLQQETKYLEEREKQKSNANEHPEINQSLSESQNGTQQYPESSSKTHTEAEDEEREFWEKPCPFTPESRLEAHRHLEEKRRANEKEKEKPKTKTPRTLITPDGRVLNVNEPKLDFSLFEDENNCLLLDLHVYRHMDSSLLDVDVQPMYVRVTVKGKVFQLVLPAEVKPDSSSAQRSQTTGHLLLILPLANEDVKPKKRTIRPTSVTSNQNNKKDTRAAPRRELLEVDPGLAGSLANIVPKGQESSHNPQRCGLEERPVSKDFVDDPEVPPLM

lrrc6

Protein tilB homolog

383 amino acids

Involved in the regulation of the cell cycle; is required for the basal body replication and new flagellum biogenesis.

Belongs to the tilB family.

44.316 kDa

MGRITTDLLRRRAEHNEGCLSNLKEVALHQQDIERIELIGDACRELEILYLCNNYISRIEGLQHLKYLKYLNLAVNNITYIEGLEGCEALERLDLTLNFVADVTCVERLRANAFLDQLHLTGNPCTKVAGYRAYVVHALPQLRELDGEEVIKTERLEARQSKDDISVAVNEEALRLQKRSVSSQRWLHEALTAFPPRYNEKGERLYGHTPEERLQMLREKEEEERRKREEQRERERSSQFGAIREELERKPQRLTAEEEIAKHGRLLLRNEPKLPFTLDEEADDGEAVVLTVKVPRFLSTTLIDVQVEVNYIRVFVKEKLIQVPLSQEVAPSGVNVQRSSVNGELRIRIPYAPHVLQEVSEARRRRQRLLGLLSDDKNEDGTG