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LNTX7

Gene
LNTX7
Protein
Long neurotoxin 7
Organism
Naja sputatrix
Length
90 amino acids
Function
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
Similarity
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
Mass
9.841 kDa
Sequence
MKTLLLTLVLVTIMCLDLGYTIRCFITPDVTSTDCPNGHVCYTKTWCDGFCSSRGRRVELGCAATCPTVKPGVDIQCCSTDNCNPFPTRP