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LEPROT

Gene
LEPROT
Protein
Leptin receptor gene-related protein
Organism
Bos taurus
Length
131 amino acids
Function
Negatively regulates leptin receptor (LEPR) cell surface expression, and thus decreases response to leptin/LEP. Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability (By similarity).
Similarity
Belongs to the OB-RGRP/VPS55 family.
Mass
14.228 kDa
Sequence
MAGVKALVALSFSGAIGLTFLMLGCALEDYGVYWPLFVLIFHAISPIPHFIAKRATYDSDATSSACRELAYFFTTGIVVSAFGFPVILARVSVIKWGACGLVLAGNAVIFLTIQGFFLVFGRGDDFSWEQW

Gene
LEPROT
Protein
Leptin receptor gene-related protein
Organism
Gallus gallus
Length
131 amino acids
Function
Involved in protein trafficking. May be involved in the down-regulation of membrane protein levels (By similarity).
Similarity
Belongs to the OB-RGRP/VPS55 family.
Mass
14.389 kDa
Sequence
MAGIKALVGLSFSGAIGLTFLMLGCALEYYGVYWPMFVLIFYFICPIPHFIARRVSDDSDAASSACRELAYFFTTGIVVSAFGFPIILARVEAIKWGACGLVLAGNAVIFLTILGFFLVFGRGDDFSWEQW

Gene
LEPROT
Protein
Leptin receptor gene-related protein
Organism
Homo sapiens
Length
131 amino acids
Function
Negatively regulates leptin receptor (LEPR) cell surface expression, and thus decreases response to leptin. Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability.
Similarity
Belongs to the OB-RGRP/VPS55 family.
Mass
14.254 kDa
Sequence
MAGVKALVALSFSGAIGLTFLMLGCALEDYGVYWPLFVLIFHAISPIPHFIAKRVTYDSDATSSACRELAYFFTTGIVVSAFGFPVILARVAVIKWGACGLVLAGNAVIFLTIQGFFLIFGRGDDFSWEQW

Gene
LEPROT
Protein
Leptin receptor gene-related protein
Organism
Meleagris gallopavo
Length
131 amino acids
Function
Involved in protein trafficking. May be involved in the down-regulation of membrane protein levels (By similarity).
Similarity
Belongs to the OB-RGRP/VPS55 family.
Mass
14.389 kDa
Sequence
MAGIKALVGLSFSGAIGLTFLMLGCALEYYGVYWPMFVLIFYFICPIPHFIARRVSDDSDAASSACRELAYFFTTGIVVSAFGFPIILARVEAIKWGACGLVLAGNAVIFLTILGFFLVFGRGDDFSWEQW

Gene
Leprot
Protein
Leptin receptor gene-related protein
Organism
Mus musculus
Length
131 amino acids
Function
Negatively regulates leptin receptor (LEPR) cell surface expression, and thus decreases response to leptin. Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability.
Similarity
Belongs to the OB-RGRP/VPS55 family.
Mass
14.316 kDa
Sequence
MAGVKALVALSFSGAIGLTFLMLGCALEDYGVYWPLFVLIFYVISPIPYFIAKRVTYDSDATSSACRELAYFFTTGIVVSAFGLPVVLARVDVIKWGACGLVLAGNAVIFLTIQGFFLVFGRGDDFSWEQW

Gene
LEPROT
Protein
Leptin receptor gene-related protein
Organism
Sus scrofa
Length
131 amino acids
Function
Negatively regulates leptin receptor (LEPR) cell surface expression, and thus decreases response to leptin/LEP. Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability (By similarity).
Similarity
Belongs to the OB-RGRP/VPS55 family.
Mass
14.198 kDa
Sequence
MAGVKALVALSFSGAIGLTFLMLGCALEDYGVYWPLFVLVFHALSPIPHFIAKRATYDSDATSSACRELAYFFTTGIVVSAFGFPVILARVAVIKWGACGLVLAGNAVIFLTIQGFFLVFGRGDDFSWEQW

Gene
Leprot
Protein
Leptin receptor gene-related protein
Organism
Rattus norvegicus
Length
131 amino acids
Function
Negatively regulates leptin receptor (LEPR) cell surface expression, and thus decreases response to leptin (By similarity). Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability.
Similarity
Belongs to the OB-RGRP/VPS55 family.
Mass
14.32 kDa
Sequence
MAGVKALVALSFSGAIGLTFLMLGCALEDYGVYWPLFVLIFYVISPIPYFIAKRVTYDSDATSSACRELAYFFTTGIVVSAFGFPVILARVAVIKWGACGLVLAGNAVIFLTIQGFFLVFGRGDDFSWEQW

Gene
leprot
Protein
Leptin receptor gene-related protein
Organism
Danio rerio
Length
130 amino acids
Function
Involved in protein trafficking. May be involved in the down-regulation of membrane protein levels (By similarity).
Similarity
Belongs to the OB-RGRP/VPS55 family.
Mass
14.13 kDa
Sequence
MAGIKALVALSFSGALGLTFLLLGCALEQFGQYWPMFVLIFYILSPIPNLIARRHADDTESSNACRELAYFLTTGIVVSAYGLPVVLARKAVIQWGAAGLVMAGNCVIFLTILGFFLIFGGGDDFSWEQW

Gene
leprot
Protein
Leptin receptor gene-related protein
Organism
Takifugu rubripes
Length
130 amino acids
Function
Involved in protein trafficking. May be involved in the down-regulation of membrane protein levels (By similarity).
Similarity
Belongs to the OB-RGRP/VPS55 family.
Mass
13.992 kDa
Sequence
MAGIKALVGLSFSGAMGLTLLLLGCALEQYGIYWPLFVLIFYVLSPIPTFISRRLSDGGSSSNACRELAYFLTTGIVVSSFGLPIVLARTATIQWGACGLVMTGNAVIFLTIFGFFVVFGGGDEFSWEQW