lcb2

Serine palmitoyltransferase 2

603 amino acids

Catalytic subunit of serine palmitoyltransferase (SPT), which catalyzes the committed step in the synthesis of sphingolipids, the condensation of serine with palmitoyl CoA to form the long chain base 3-ketosphinganine.

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

67.519 kDa

MAQADFVSPTSIDVSEKKEVEFHKKVDHVENPPLSTESAKLEAEEVAAEKLNSEHLLENEFAPITDPTHRRVSKNPDGAELFQFEDEPSYYYVVATYLTYLVLIIIGHVRDFFGKRFHKDDYKYLKDNDGYAPLYNHFDNFYVRRLQHRINDCFSRPTMGVPGRVIRLMNRYSTDSNSTFKLTGDTSLALNVSSYNYLGFAQSHGPCATKVEEAMQKYGLSTCSSNAICGTYGLHKEVEELTANFVGKPAALVFSQGFSTNATVFSTLMCPGSLIISDELNHTSIRFGARLSGANIRVYKHNDMTDLERVLREVISQGQPRTHRPYSKILVVIEGLYSMEGNFCDLPKVVELKNRYKFYLFIDEAHSIGAIGPRGGGICDYFGISTDHVDILMGTFTKSFGAAGGYISATPNIINKLRVTNPGYVYAESMSPAVLAQIKSSFLEIMDNSPTSAGLERIERLAFNSRYIRLGLKRLGFIIFGNDDSPVVPLLLYNPGKINAFSHEMLKRGIAVVVVGYPACPLLTSRVRFCFSASHNKADMDYFLRACDEVGEKLQLKFSTGAAGEDVGKTNVEKMKKNQGWFKPPRWKIEDVLKHGVHDALTQ

LCB2

Serine palmitoyltransferase 2

562 amino acids

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

62.937 kDa

MISISSTRVPLIPPEDIPLEDKKENEFGQLTSEEYLYQSKSRDGKALQDPILDAPAYHVSLITYLNYLILIILGHIHDFLGLTFQKEKHKDIMEQDGLAPWFSTFESFYVRRLKQRIDDCFSRPTTGVPGRFIRCLDRVSHNLNDYFTYPGTTSMCLNLSSYNYLGFAQSEGQCTTAALEATDKYGVYSGGPRTRIGTTDLHVMTEKYVAQFVGKEDAILFSMGYGTNANFFNSFLDSKCLVISDSLNHTSIRTGVRLSGAAVKTFKHNDMRALEKLIREQIVQGQSKTHRPWKKIIICVEGLYSMEGTMANLPKLVELKKKYKCYLFVDEAHSIGAMGPSGRGVCDFFGIPCSDIDIMMGTLTKSFGAAGGYIAADKWIIDRFRLDLTTPHYGEPTPAPVLAQIASSLKTITGDINPGEGQERLQRIAFNARYLRLALQRLGFIVYGIADSPVIPMLLYAPSKMPAFSRMMLQRKIAVVVVAYPATPLIESRVRFCVSAALTKEDIDYLLQHINEVGDKLFLKVSSGKAGGSLDGKPPRWNIDEVIKRTPTDCKDDSFFRI

LCB2

Serine palmitoyltransferase 2

561 amino acids

Catalytic subunit of serine palmitoyltransferase (SPT), which catalyzes the committed step in the synthesis of sphingolipids, the condensation of serine with palmitoyl CoA to form the long chain base 3-ketosphinganine.

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

63.111 kDa

MSTPANYTRVPLCEPEELPDDIQKENEYGTLDSPGHLYQVKSRHGKPLPEPVVDTPPYYISLLTYLNYLILIILGHVHDFLGMTFQKNKHLDLLEHDGLAPWFSNFESFYVRRIKMRIDDCFSRPTTGVPGRFIRCIDRISHNINEYFTYSGAVYPCMNLSSYNYLGFAQSKGQCTDAALESVDKYSIQSGGPRAQIGTTDLHIKAEKLVARFIGKEDALVFSMGYGTNANLFNAFLDKKCLVISDELNHTSIRTGVRLSGAAVRTFKHGDMVGLEKLIREQIVLGQPKTNRPWKKILICAEGLFSMEGTLCNLPKLVELKKKYKCYLFIDEAHSIGAMGPTGRGVCEIFGVDPKDVDILMGTFTKSFGAAGGYIAADQWIIDRLRLDLTTVSYSESMPAPVLAQTISSLQTISGEICPGQGTERLQRIAFNSRYLRLALQRLGFIVYGVADSPVIPLLLYCPSKMPAFSRMMLQRRIAVVVVAYPATPLIESRVRFCMSASLTKEDIDYLLRHVSEVGDKLNLKSNSGKSSYDGKRQRWDIEEVIRRTPEDCKDDKYFVN