Kiaa0753

Gene

KIAA0753

Protein

Protein moonraker

Organism

Homo sapiens

Length

967 amino acids

Function

Involved in centriole duplication. Positively regulates CEP63 centrosomal localization. Required for WDR62 centrosomal localization and promotes the centrosomal localization of CDK2 (PubMed:24613305, PubMed:26297806).

Mass

109.407 kDa

Sequence

MGPGQPASTCVHLAPRTQLDGRSDPKVLQTQNQLQFNRNVPTHSSNLAIRYSCPHAIRIEKLKHSYNESYHCKDADCRVGPDLGSSVSFSVISQERLSYAVHLARRDVKRRQFEKHIKEHHLRSQPQSSQKCGHTKYKIPDHRVERKESKSQAACQCSHQPSKVEISSSGAKVYLYSSHPGQSDLTVPNSPPTHDPGLQPHPRIGDHKNISEQKSLLEVQRLQKELSSCIHKIEEVTKKDRLEEALDPDEERRIRIRRQEQAARSARMLYVLQQQVKEIQEELDKLSPHKIKHTKKSWAMSKLAAAHRGAIRALQMFVTQFTDRGEHPLPARCKELGSLIRQLSLCSVKLDADPSVPDVVIDILQQIEALESLLEKKLSPKKVKKCFSEIRSRFPIGSQKALERWPSTSPKGERRPLTAKDTFPQETSRPSVAKQLLADKYQPDTELPETQRLQSELDVLDADIVLEEGPFILDQSASFKDEVLAVAKTKAGKKKPVTENVPFRKKDTLAPARQQGLRKAERGRQSQPHSKSRVQQTTVSSRLKMNRQPVKDRKAPWIPPNPTSPPASPKCAAWLKVKTSPRDATKEPLQQEDPQEESHLTGAVEHEAARLAWLDAETSKRLKELEELKAKEIDSMQKQRLDWLDAETSRRTKELNELKAEEMYRLQQLSVSATHLADKVEEAVLDRLKPLLVKAQRVNSTTEANIHLKDGSSVNTAKAQPAQEVAAVDFESNNIRQLDDFLEDCASELWAVTHAKILGSETLATVEDSKDSPDLEIMMRRMEEMEKYQESVRQRYNKIAYADPRLWMQEENNDQKISAISEKPLSPHPIRITKTVDRKDPAVNIMLERPCNGNSLDESVGTEEGSEKREAPLLSLAEDSQQKEGRAPLFVPPGMQHSIGDYCSRFEQYLRIISHEAVGSFNPWLIAESFSEELVDEALGAVAAELQDMCEDYAEAVFTSEFLEAAT

Protein

Protein moonraker: KIAA0753

Gene

Kiaa0753

Protein

Protein moonraker

Organism

Mus musculus

Length

959 amino acids

Function

Involved in centriole duplication. Positively regulates CEP63 centrosomal localization. Required for WDR62 centrosomal localization and promotes the centrosomal localization of CDK2.

Mass

108.875 kDa

Sequence

MGPSQPASTCVHLAPSLQLDAMSDPRNLQPQNQLQFNRNVPTNPRNLAVRYSCPHGIKIEKLKHSYNELNHGKDLDFKAGNELSSSVSFSVISEERLSYAVHLAKRDVKRRQFEEHVKDHLRSLPHSSHKGMHTKVERKDSKSQDVCHCSHQPSRVSLSSSGAKVYVYTSQPGRSDLTVPNSPPTHDPGLQLQPRIEENKNLWEQKGLLEVQRLQKELSGCIRKIEALTKKDRLEEALDPDEEHRIRVRRQEQAVRCARMLYVLQQQVKEIQEELDKLSPQKIKHTKKSWAVSRLAAAHRAAIRALQVFVTQFTDRGEHPVPARCRELGSLIRQLSLCSAKLDADPSVPDVVIDILQQIEALESLLEKKLSPKKAKKCFTEIRSRFPVGSQKILERWPTVLPKSERRHLVTKETFPQETSRPPVAKRLLAAMCQPDGELQRLESEPDVLDAHLLPEEAPRIEDNGTDFKDGTLTPAKPQAVRRKALTGSMPIRKKDTVESARPQQGLHIAERNRPNQPYSKSRLQQTTVSSRLKMNRQPMKDHRAPWIPPNPTSPPASPKCAAWMKVKYSPRDAAKEQSLQQEDIHKESQLRGDAEQEAARLSWPDAESSKRLKELEELEAKEMERKQKQRLNWLEAETSRRTKELDELKAEEMDRLQKLSVSATQLADKVEEAVLERLKPLLIKAQRVNSSVEANSHLKDRPSRHAAAAAQPAEQASDVPFESRNIPQLRDCLEDTAHELWARTQDKILGSETSARLGDSKDSPDLETMMLRMEEMEKYQETVRQRYNKIVYADPHLWMHEERNDQNTPAVSEGPLASHPIKITKTATQKCPAVNILLERPCNANSLDESVTTEEGSEKREAPLPLSREDLHQRKGQTPLSVPPRMRHSIGAYCSRFEQFLRIIAHEAIGSFNPWLIAESFSDELVDEALGAVAAELQDVCEDYAEAVFTSEFLEAAA

Protein

Protein moonraker: Kiaa0753