Protein
Potassium channel toxin alpha-KTx 3.9
Organism
Buthus occitanus tunetanus
Function
Binds and inhibits potassium channels. Intracerebroventricular injection into mice induces paralyzing symptoms followed by death. Its binding affinity to rat brain synaptosomes is 5-fold lower than this of KTX 1.
Similarity
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 03 subfamily.
Sequence
VGIPVSCKHSGQCIKPCKDAGMRFGKCMNRKCDCTPK