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KTX3

Gene
KTX3
Protein
Potassium channel toxin alpha-KTx 3.9
Organism
Buthus occitanus tunetanus
Length
37 amino acids
Function
Binds and inhibits potassium channels. Intracerebroventricular injection into mice induces paralyzing symptoms followed by death. Its binding affinity to rat brain synaptosomes is 5-fold lower than this of KTX 1.
Similarity
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 03 subfamily.
Mass
4.028 kDa
Sequence
VGIPVSCKHSGQCIKPCKDAGMRFGKCMNRKCDCTPK