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KRTAP21-1

Gene
Krtap21-1
Protein
Keratin-associated protein 21-1
Organism
Mus musculus
Length
128 amino acids
Function
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Similarity
Belongs to the KRTAP type 21 family.
Mass
12.539 kDa
Sequence
MCCNYYGNSCGGCGYGSRYGYGCGYGSGYGCGYGSGYGCGYGSGYGCGYGSGYGCGYGSGYGCGYGSGYGCGYGSGYGCGYGSGYGCGYGSGYGCGYGSGYGCGYGSRYGCGYGSGCCSYRKCYSSCC

Gene
KRTAP21-1
Protein
Keratin-associated protein 21-1
Organism
Homo sapiens
Length
79 amino acids
Function
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Mass
7.937 kDa
Sequence
MCCNYYGNSCGYGSGCGCGYGSGSGCGCGYGTGYGCGYGCGFGSHYGCGYGTGYGCGYGSGSGYCGYRPFCFRRCYSSC