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KRT1

Gene
KRT1
Protein
Keratin, type II cytoskeletal 1
Organism
Homo sapiens
Length
644 amino acids
Function
May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK.
Similarity
Belongs to the intermediate filament family.
Mass
66.039 kDa
Sequence
MSRQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKFVSTTYSGVTR
Protein
Keratin, type II cytoskeletal 1: KRT1

Gene
Krt1
Protein
Keratin, type II cytoskeletal 1
Organism
Mus musculus
Length
637 amino acids
Function
May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK (By similarity).
Similarity
Belongs to the intermediate filament family.
Mass
65.606 kDa
Sequence
MSLQCSSRSLCRGGGGSRNFSSGSAGLVSFQRRSTSSSMRRSGGGGGGRFSGGGFCGSSGSGFGSKSLMNLGGGRSISKSVAGGGGSFCGGFGGGSYGGGGFGGGSYGGGGFGGGSFGGGGFGGSGFGGGLGGGGGFGSGGGFGGGRFGSMGPVCPPGGIQEVTINQSLLQPLNVEVDPQIQKVKSQEREQIKSLNDKFASFIDKVRFLEQQNQVLQTKWELLQQVDTTTRTQNLDPFFENYISILRRKVDSLKSDQSRMDSELKNMQDLVEEYRTKYEDEINKRTNAENEFVTIKKDVDSAYMTKVELQAKADALQQDIDFFSALYQMEMSQMQTQISETNVVLSMDNNRSLDLDGIISEVKAQYDSICQRSKAEAETFYQSKYEELQITAGKHGDSVRNTKMEISELNRMIQRLRSEIDGCKKQISQIQQNINDAEQRGEKALKDAQNKLNEIEDALSQCKEDLARLLRDFQELMNTKLALDMEIATYKKLLEGEEIRMSGECTPNVSVSVSTSHTSMSGSSSRGGGSGGGRYGGGGSYGGGSGGGSYGGSSGGGGSGGSYGGGSGGGSYGGGSGGGSSGSHRGGSGGGGGSSGGSYGGSSGGGRGGSSSGGGGVKSSGSSTVKFVSTSYSRGTK
Protein
Keratin, type II cytoskeletal 1: Krt1

Gene
KRT1
Protein
Keratin, type II cytoskeletal 1
Organism
Pan troglodytes
Length
637 amino acids
Function
May regulate the activity of kinases such as PKC and SRC via binding to integrin beta 1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK (By similarity).
Similarity
Belongs to the intermediate filament family.
Mass
65.489 kDa
Sequence
MSRQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGSGIGGGGFGGFGSGGGGFGGGGFGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELNNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIATYRTLLEGEESRMSGECAPNVGVSVSTSHTTISGGGGRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKFVSTTYSGVTR
Protein
Keratin, type II cytoskeletal 1: KRT1

Gene
Krt1
Protein
Keratin, type II cytoskeletal 1
Organism
Rattus norvegicus
Length
625 amino acids
Function
May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK (By similarity).
Similarity
Belongs to the intermediate filament family.
Mass
64.831 kDa
Sequence
MSFQCSSRSLCRSGGGGGGRNFSSGSAGLVSFQRRSTSSSMRRSGGGGGGRFSGGGFCGSSGGGFGSKSLVNLGGGRSISISVAGGGSSYGGGFGGGSYGGGSFGGGSFGGGVGGGFGGGGFGGGGFGSGGGFGGGRFGGGFGPVCPPGGIQEVTINQSLLQPLNVEVDPQIQKVKSQEREQIKSLNDKFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTQNLDPFFESYISNLRRQVDSLKNDQSRMDSELKNMQDLVEEYRTKYEDEINKRTNAENEFVTIKKDVDSAYMNKAELQARVDNLQQDIDFFSTLYQMELSQMQTQISETNVVLSMDNNRTLDLDGIIAEVKAQYDSICQRSKAEAETFYQSKYEELQITAGKHGDSVKNTKMEISELNRVIQRLRSEIDSVKKQISQMQQNISDAEQRGEKALKDAQNKLNEIEDALTQAKEELTRLLRDYQELMNTKLALDMEIATYRKLLEGEEIRMSGECTPNVSVSVSTSHTSMSGTSSRGGGRYGSGGGGGGGTYGGGSRGGSYGGGSGGGSYGGCSSGGGSGGGSYGGGSSGGHRGGSGGGGGSSGGSYGGSSGGGRGGSSSGGGVKSSGSSSVKFVSTTYSRGTN
Protein
Keratin, type II cytoskeletal 1: Krt1

Gene
KRT1
Protein
Keratin, type II cytoskeletal 1
Organism
Canis lupus familiaris
Length
619 amino acids
Function
May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK (By similarity).
Similarity
Belongs to the intermediate filament family.
Mass
63.79 kDa
Sequence
MSRHFSSRSGFRSGGGFSSGSAGLVSFQRRTTSSSVRHSGGGGGRFSGGRCGGGGGGGAGGGGFGSRSLVNLGGSKSISISVAGGGGGRGGFGGGYGGGGFGGGGFGGGSGGFGLGGGFGGGGFGGGGFGGGGFGGGGFGGGSFGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKTREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHSLEPYFENYISNLRRRVDQLKSDQSRMDSELKNMQDLVEDYRNKYEDEINKRTNAENEFVTIKKDVDAAFMNKVDLQAKVDNLQQEIDFLTTLYQAELSQMQTQISETNVILSMDNNRSLDLDSIISEVKAQYEEIAQKSKAEAEALYQTKYEELQITAGKHGDNLKSTKMEISELNRVAQRLRSEIDSVKKQISALQQSISDAEQRGENALKDAQSKLAELEDALQKAKEDMARLLRDYQELMNTKLALDMEIATYRTLLEGEESRMSGECAPNVSVSVNTSHTTISGGGGRGGGGFGSVGGGGGYGGGSYGSGGGSYGSGGGGGGSYGSGGGGGGGYGSSSSSGGHRGGSGGGSRSGGSSGGRGSSSGGIKTSSGSSSVKFVSTSYSRAVR
Protein
Keratin, type II cytoskeletal 1: KRT1