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KLLA0E13333g

Gene
KLLA0E13333g
Protein
Succinate dehydrogenase assembly factor 2, mitochondrial
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
163 amino acids
Function
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
Similarity
Belongs to the SDHAF2 family.
Mass
19.057 kDa
Sequence
MLRTVFNKPSVLKSGVNSITKQCRSLHANAYLLNKGNSNGAEGQDDDVTVRIRIPPIKRTGESLDKKRARLIYQSRKRGILETDLLLSRFAAKYLKEMTPEQLEEYDQLLNELDWDIYYWATENYSITPLPDRWKNSNILKQLQEFSKNKDREILSMPDLSKY