Function
Acts as a plus-end microtubule-dependent motor protein (PubMed:25159991). Involved in the control of root hair tip growth by promoting microtubule depolymerization and limiting the accumulation of endoplasmic microtubules (PubMed:17957256, PubMed:17971038, PubMed:24400013, PubMed:25159991). In vitro, binds to polymerized actin through ARM repeats, and to polymerized tubulin through N-terminal motor domain (PubMed:17957256).
Sequence
MSSSNSSSAVRSSAKHAAERIQQHLPPNSNHAVSLSSSSLNLPARTSIVAPGIAHSSRLKDRPSASSSSSSSSVSASSPSTRRSGTPVRRSQSKDFDDDNDPGRVRVSVRVRPRNGEELISDADFADLVELQPEIKRLKLRKNNWNSESYKFDEVFTDTASQKRVYEGVAKPVVEGVLSGYNGTIMAYGQTGTGKTYTVGKIGKDDAAERGIMVRALEDILLNASSASISVEISYLQLYMETIQDLLAPEKNNISINEDAKTGEVSVPGATVVNIQDLDHFLQVLQVGETNRHAANTKMNTESSRSHAILTVYVRRAMNEKTEKAKPESLGDKAIPRVRKSKLLIVDLAGSERINKSGTDGHMIEEAKFINLSLTSLGKCINALAEGSSHIPTRDSKLTRLLRDSFGGSARTSLIITIGPSARYHAETTSTIMFGQRAMKIVNMVKLKEEFDYESLCRKLETQVDHLTAEVERQNKLRNSEKHELEKRLRECENSFAEAEKNAVTRSKFLEKENTRLELSMKELLKDLQLQKDQCDLMHDKAIQLEMKLKNTKQQQLENSAYEAKLADTSQVYEKKIAELVQRVEDEQARSTNAEHQLTEMKNILSKQQKSIHEQEKGNYQYQRELAETTHTYESKIAELQKKLEGENARSNAAEDQLRQMKRLISDRQVISQENEEANELKIKLEELSQMYESTVDELQTVKLDYDDLLQQKEKLGEEVRDMKERLLLEEKQRKQMESELSKLKKNLRESENVVEEKRYMKEDLSKGSAESGAQTGSQRSQGLKKSLSGQRATMARLCEEVGIQKILQLIKSEDLEVQIQAVKVVANLAAEEANQVKIVEEGGVEALLMLVQSSQNSTILRVASGAIANLAMNEKSQDLIMNKGGAQLLAKMVTKTDDPQTLRMVAGALANLCGNEKFLKLLKEEEGIKGLLTMAQSGNIDIIAQVARGMANFAKCETREIMQGRRKGRSLLLEEGVLEWLTSNSHIDSASTQRHIELALCHLAQNEENANDFKRTGSVTEIVRISVESSRDDIRSLAKKILKTNPYFSS