KIF25

Kinesin-like protein KIF25

586 amino acids

Minus-end microtubule-dependent motor protein (PubMed:28263957). Acts as a negative regulator of centrosome separation required to prevent premature centrosome separation during interphase (By similarity). Required to maintain a centered nucleus to ensure that the spindle is stably oriented at the onset of mitosis (By similarity). May also act as a negative regulator of amino acid starvation-induced autophagy (By similarity).

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

64.008 kDa

MPAGGGRWGSFWEQRTRQLQSQVRAKEDKIAELETENAVLLLKLAEYKGKIEKSRSEATRISTLYNKQQRLQRNTRSALSQLDGVIQKLNQDIQAFHSSSRALLRDYQDEYQDRVSAIVTAVQRTRQSAETLLACQAKVVHLEQALQDVSARHQLERQRRKALHNSLVELRGNIRVHCRIRPLLPFDSESDDPVLQSSSISREVAHAVDDETVLVKCDRPGHPLINKTYHFERVYGPAESQSAVFGDVCPLLTSLLDGYNVCVMAYGQTGSGKSYTMLGPHSDDGPVLPLDPQSDLGIIPRAAEELFRLISENPSRSPKVEVSIVEVYNNDIFDLLAKDTVAAVSGVKREVMTAKDGRTEVALLASEAVGSASKLMELVRGGLQLRAKHPTLVHADSSRSHLIITVTLTTAACSDSTADQACSATHPGEQTEAGRAGRSRRTSQGASAPQPVPGDPAGRAEQVQARLQLVDLAGSECIGVSGVTGSALRETACINRSLAALADVLGALSEHRSHIPYRNSRLTHLLQDCLGGDAKLLVILCISPSQRHLAQTLQGLGFGIRARQVQRGPARKRPPSSQMEGKRRPD

KIF25

Kinesin-like protein KIF25

384 amino acids

Minus-end microtubule-dependent motor protein (By similarity). Acts as a negative regulator of centrosome separation required to prevent premature centrosome separation during interphase (PubMed:28263957). Required to maintain a centered nucleus to ensure that the spindle is stably oriented at the onset of mitosis (PubMed:28263957). May also act as a negative regulator of amino acid starvation-induced autophagy (PubMed:22354037).

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

40.686 kDa

MTWTSGQLQREKQARPGSGAVLAFPDDKDLRVYGPAESQSAVFGDVCPLLTSLLDGYNVCVMAYGQTGSGKSYTMLGRHSDDGPVLPLDPQSDLGIIPRVAEELFRLILENTSRSPKVEVSIVEVYNNDIFDLLAKDSIAAVSGVKREVVTAKDGRTEVALLASEAVGSASKLMELVHGGLQLRAKHPTLVHADSSRSHLIITVTLTTASCSDSTADQACSATLPREQTEAGRAGRSRRASQGALAPQLVPGNPAGHAEQVQARLQLVDSAGSECVGVSGVTGLALREMACISRSLAALAGVLGALLEHRGHAPYRNSRLTHLLQDCLGGDAKLLVILCISPSQRHLAQTLQGLGFGIRARQVQRGPARKKPPSSQTEGKRRPD