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KCNMB2

Gene
KCNMB2
Protein
Calcium-activated potassium channel subunit beta-2
Organism
Homo sapiens
Length
235 amino acids
Function
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.
Similarity
Belongs to the KCNMB (TC 8.A.14.1) family. KCNMB2 subfamily.
Mass
27.13 kDa
Sequence
MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYFLLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEGNQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
Protein
Calcium-activated potassium channel subunit beta-2: KCNMB2

Gene
Kcnmb2
Protein
Calcium-activated potassium channel subunit beta-2
Organism
Mus musculus
Length
235 amino acids
Function
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex (By similarity).
Similarity
Belongs to the KCNMB (TC 8.A.14.1) family. KCNMB2 subfamily.
Mass
27.12 kDa
Sequence
MFIWTSGRTSSSYRQDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYFLLGITLLRSYMQSVWTEEAQCALLNVSITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSSGERLLLYHTEETMKINQKCSYIPKCGNNFEESMSLVSVVMENFRRHQHFPCYSDPEGNQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
Protein
Calcium-activated potassium channel subunit beta-2: Kcnmb2

Gene
Kcnmb2
Protein
Calcium-activated potassium channel subunit beta-2
Organism
Rattus norvegicus
Length
235 amino acids
Function
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex (By similarity).
Similarity
Belongs to the KCNMB (TC 8.A.14.1) family. KCNMB2 subfamily.
Mass
27.154 kDa
Sequence
MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYFLLGITLLRSYMQSVWTEEAQRALLNVSITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSSGEKLLLYHTEETMKINQKCSYIPKCGNNFEESMSLVSVVMENFRRHQHFPCYSDPEGNQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR
Protein
Calcium-activated potassium channel subunit beta-2: Kcnmb2