KAP4

Kinetoplast-associated protein 1

151 amino acids

Histone H1-like DNA-binding protein involved in the organization and segregation of kinetoplast DNA (kDNA). The mitochondrial DNA of kinetoplastid protozoa consists of about 5,000 minicircles and 20 to 30 maxicircles. These circular DNAs are held together by catenation into a highly organized compact disk structure referred to as a kinetoplast DNA (kDNA) network. Binds preferentially to a specific fragment of minicircle DNA and is able to compact kDNA networks through DNA charge neutralization and condensation (By similarity).

Belongs to the KAP family.

14.974 kDa

MLRVSVRSLVRKASSKAGSKAAVPAAAAAASAPLSPATSAASARAVPPVGESRVSIPPIPGVAAPRSHRAAAAPAKKAAAPKAAKAKTPAKASRKIKKAASKPSAPKQAAGKMRKAAGKAQRKIKAAARKAAPKKMAKSFGKKGAAKKAHK

KAP4

Kinetoplast-associated protein 4

128 amino acids

Histone H1-like DNA-binding protein involved in the organization and segregation of kinetoplast DNA (kDNA). The mitochondrial DNA of kinetoplastid protozoa consists of about 5,000 minicircles and 20 to 30 maxicircles. These circular DNAs are held together by catenation into a highly organized compact disk structure referred to as a kinetoplast DNA (kDNA) network. Binds preferentially to a specific fragment of minicircle DNA and is able to compact kDNA networks through DNA charge neutralization and condensation.

Belongs to the KAP family.

14.59 kDa

MLRFVPRRLAIGAYTLFMMEQKNNPKLKGLKIADRGKMTSKLYKALNPNDKAALEKRAAAHPGFKRKEKEPKELKAAKAAKTSTPRAPSEYAKFVQANIGRFEKLPHLDRMKAVAKLWKQQQMRTGKP