Protein
Ent-kaurenoic acid oxidase
Organism
Oryza sativa subsp. japonica
Function
Involved in gibberellin (GA) biosynthesis. Catalyzes three successive oxidations of ent-kaurenoic acid giving gibberellin 12 (GA12), a key step in GAs biosynthesis. GAs, which are involved many processes, including stem elongation, play a central role in plant development (Probable). Required for pollen germination and elongation (PubMed:18083909).
Similarity
Belongs to the cytochrome P450 family.
Sequence
MVMEGMGMAAAWAAGDLWVLAAAVVAGVVLVDAVVRRAHDWVRVAALGAERRSRLPPGEMGWPMVGSMWAFLRAFKSGNPDAFIASFIRRFGRTGVYRTFMFSSPTILAVTPEACKQVLMDDEGFVTGWPKATVTLIGPKSFVNMSYDDHRRIRKLTAAPINGFDALTTYLSFIDQTVVASLRRWSSPESGQVEFLTELRRMTFKIIVQIFMSGADDATMEALERSYTDLNYGMRAMAINLPGFAYYRALRARRKLVSVLQGVLDGRRAAAAKGFKRSGAMDMMDRLIEAEDERGRRLADDEIVDVLIMYLNAGHESSGHITMWATVFLQENPDIFARAKAEQEEIMRSIPATQNGLTLRDFKKMHFLSQVVDETLRCVNISFVSFRQATRDIFVNGYLIPKGWKVQLWYRSVHMDDQVYPDPKMFNPSRWEGPPPKAGTFLPFGLGARLCPGNDLAKLEISVFLHHFLLGYKLKRANPKCRVRYLPHPRPVDNCLATITKVSDEH