Protein
Nuclear migration protein JNM1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Function
Component of the dynactin complex which assists cytoplasmic dynein by increasing its processivity and by regulation of its cargo binding (By similarity). The dynactin complex is required for the spindle translocation late in anaphase and is involved in a cell wall synthesis checkpoint. JNM1 is associated with the rod and links it to the projecting sidearm. Required for proper nuclear migration during the mitotic cell cycle and for astral microtubule development.
Sequence
MNVIDLSDPAINVDYDSLIGIDNEESQEIFENEVKEDGQQEEQEEASSRKDGLIVEPGRDVESLRRAIRDQLLFKIHRQNQSDCADARKLSNDEEDESRQQKLERIREELEELKIENLTSEMQTEIKELCEIQSKLATESSSRLTNLRKKLLETYEGQDTVILPNIILDTSNIKRLQKLDQKISLMERFVGIPEALEAEEDRKSVHSKVNELYRSIQLLQGDDKAEGKLQKFRDRLVELNEEFENSLLGKKIQQDLRLKDDTVSKLVMPENKVKEINSMYSMFKQYQDSLPLLAERMKSLNKMNNRVIEVYETTKGLDSQITSIQEQGKVWLKALNELDKKFDEQEVKIRENMEQIRRKIDTLEDEALQRNSK