Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Function
May be required for vacuolar fusion. Overexpression leads to fragmentation of vacuoles, missorting of the vacuolar enzyme carboxypeptidase Y (CPY) to the exterior of the cell and accumulation of multivesicular bodies inside the cell.
Sequence
MPDNNTEQLQGSPSSDQRLRVDWDNGNHFDVSPDRYAPHLSEFYPIVNSKRPVASSAGSENNDHLDDMNHLRSSKVYSKARRASSITSGTSTINDLQTLITKRDVKETQEALSTLLRNSNAYSDSLLKTSQNGAEIAHSLENIAKLKGCNDETAEKLLSASGLFYLLSNHQLIMSKYFNDLLGDNLIDDIDEFELQTKIMENKFKAQSKEQSLKLKLQERHNFDISKRKIRNLISYRESLSSLQARLDQLETLKHDFYMDSYELVENTCNKVLSKVATVSRAQVEISENIARKGWSGGGLDELLCDADDPFSKKADGPYGTIGGDGETAGEAYNSDEETGGNDVVLNELLEGTSQPSTSKTSLPKSKGSSTVSTPNHSQSSSNKDGVRNNGGGKNGEDEDTDNLMGTENSFSLPPTRNSAEETTQTFKQLSIKEDNDNHSSDTDGMQDQSSNI