IRF2BP2

Interferon regulatory factor 2-binding protein 2

587 amino acids

Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities (PubMed:12799427). Represses the NFAT1-dependent transactivation of NFAT-responsive promoters (PubMed:21576369). Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles (PubMed:20702774). Plays a role in immature B-cell differentiation (PubMed:27016798).

Belongs to the IRF2BP family.

61.025 kDa

MAAAVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLKRAHGCFPEGRSPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQALERYPLAAAAERPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAAVEHEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTVRDTLLALHQHGHSGPFESKFKKEPALTAGRLLGFEANGANGSKAVARTARKRKPSPEPEGEVGPPKINGEAQPWLSTSTEGLKIPMTPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADNAGGSHASKDANQVHSTTRRNSNSPPSPSSMNQRRLGPREVGGQGAGNTGGLEPVHPASLPDSSLATSAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDS

Irf2bp2

Interferon regulatory factor 2-binding protein 2

570 amino acids

Acts as a transcriptional corepressor in a IRF2-dependent manner, this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles. Plays a role in immature B-cell differentiation (By similarity).

Belongs to the IRF2BP family.

59.292 kDa

MAAAVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLKRAHGCFPEGRSPTGAQPAAAKPPPLSAKDLLLQPPPQLGHAGAEAARAQAMERYPLAPDRAPRLASDFSTRAGAGLPQSAAQQSAPANGILVPNGFSKLEEPPELNRQSPNPRRAHAVPPTLVPLVNGSAALGLSGRAAATLAAVSGTPGLGAQPAELGTHKRPASVSSAAAEHEAREPSKEKAQPAHRSPADSLSSAAGASELSAEGAGKGRAPGEQDWASRPKTVRDTLLALHQHGHSGPFESKFKKEPALTAAGRLLGFEANGANGSKAVARTARKRKPSPEPEGEVGPPKINGETQPWLSTSTEGLKIPITPTSSFVSPPPPTASPHSNRTTPPEAAQNGQSPMAALILVADNAGGSHASKDATQVHSTTRRNSSSPPSPSSMNQRRLGPREVGGQATGSTGGLEPVHPASLPDSSLAASAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDS

irf2bp2

Interferon regulatory factor 2-binding protein 2

537 amino acids

Acts as a transcriptional repressor.

Belongs to the IRF2BP family.

57.244 kDa

MSSATVAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRIEFVIETARHLKRAHGFQEGRSPGPSPSSSSSSSSSSSVKPQLSAKEMAQIGHTMGGPEGVTRTSQQPPPPQCLDRYSLERPPPPRLGSEYGLGRQVNGILLPNGFPKPEEPPELNRQSPNPRRTSTVPQSLGALMNGTPMGSARATIGLSGASLVAAAAATTSADLSGKRPGSVSSSEHDGKEKHRADSYSELGENHKSRAEEWISKPKTVRDTLMAMQHSHSPFDSKFKKDTGPGRVLSFEANNPVSKSGARGGRKRKTSPEPEGEGGSVKINGEGQPWLPATESLKISTMASPSFISPPSTVSPHSNRTTPPEAAQNGQSPMAALILVADNAGGNHASKDANQVHSTTRRNSSSPPSPSSMNQRRMAPRDVPSQLPSGGTSSHAGMEQGLPQSIPDSSIPNSIPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGSSGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDS

irf2bp2

Interferon regulatory factor 2-binding protein 2

537 amino acids

Acts as a transcriptional repressor.

Belongs to the IRF2BP family.

57.156 kDa

MSSATVAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRIEFVIETARHLKRAHGFQEGRSPGPSPSSSSSSSSSSSVKPQLSAKEMAQIGHTMGGPEGVTRTSQQPPPPQCLDRYSLERPPPPRLGSEYGVGRQVNGILLPNGFPKPEEPPELNRQSPNPRRTSSVPQSLGALMNGAPIGSGRTPVGLSAASLVAAAAATTSADLSGKRPGSVSSSEHDGKEKHRADSYSELGENHKSRAEEWISKPKTVRDTLMAMQHSHSPFDSKFKKDPGPGRVLSFEANNPASKSGARGGRKRKPSPEPEGEGGSVKMNGEGQPWLPAAESLKISTMASPSFISPPSTVSPHSNRTTPPEAAQNGQSPMAALILVADNAGGNHASKDANQVHSTTRRNSSSPPSPSSMNQRRMAPRDVPSQIPSGGTSSHAGMEQGHPQSIPDSSIPNSIPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGSSGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDS