IP5P1

Gene

IP5P1

Protein

Type I inositol polyphosphate 5-phosphatase 1

Organism

Arabidopsis thaliana

Length

590 amino acids

Function

Has phosphatase activity toward Ins(1,4,5)P3 and Ins(1,3,4,5)P4, but not toward Ins(1,4)P2, Ins(1)P (PubMed:11402208). Seems to be involved in the abscisic acid (ABA) signaling pathway (PubMed:12805629). Could also be able to hydrolyze PtdIns(4,5)P2 and PtdIns(3,4,5)P3 (PubMed:23658066).

Similarity

Belongs to the inositol polyphosphate 5-phosphatase family.

Mass

67.783 kDa

Sequence

MAEVRSRSRRTESNWATICCSAFSCLQLYWARIVLRKWFNVSASESDYSADSDDDYEDRSQEFDPISSGVTNPRVDTDGNVIYRPKLRRRNSETFRMQYIDTKAIRICAGTWNVGGRVPSSDLDIDGWLDTLEPADIYVLGLQEIVPLNAGNIFGMEDDQPALEWENLIRDALNRVQPRKLKIKSHSDPPSPSKFKQPEEVPYSVEDMFVETSHDACDGISSMDNKLNSVESTDVPIVSEDSLTNIDVLGSTNDNASCLPIQEYLQRQFSTPNTPDRSLSMQINSDSKREERFSYTERVGLSWPEPPLRLLNQYVSERRGSFKSVNLTITNLRKPSYVRIVSKQMVGVFLTIWVRRNLRKHISNLCVSTVGVGIMGYIGNKGSVSVSMSIYQTPFCFLCTHLSSGEKDTDQEKRNDDVREIHRRTQFLPHSLNANELPRSICNHERIIWLGDLNYRINLSYEKTHELIARKEWQRLVEYDQLSREMTKGNLFEGWSEGTLDFAPTYKYEIDSENYIGDDPESGKRRPAWCDRIIWNGKGMKLFNYRRNEIKLSDHRPVTATFLAEVEVLSPRKLQHALTLTYAEIQGLDA

Protein

Type I inositol polyphosphate 5-phosphatase 1: IP5P1