INSRR

Insulin receptor-related protein

1300 amino acids

Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB (By similarity).

Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.

144.518 kDa

MARPKLWPWGILLLVSLLSAGFNLDTMNVCPSLDIRSEVAELRRLENCSVVEGHLQILLMFTATGEDFRSLSFPHLTQVTDYLLLFRVYGLESLRDLFPNLAVIRGAHLFLGYALVIFEMPHLRDVGLPALGAVLHGSVRVEKNQELCHLSTIDWGLLQPTPSTNYIVGNKLGEECADVCPGTLGAAGEPCARTTFNGHTDYRCWTSSHCQRVCPCPQGLACTISGECCHTECLGGCSQPEDPRACVACRHFYYQSACHRACPLGTYEHESWRCVTAESCANLRSVPGRASTFGIHQGKCLAQCPPGFTRNGSSIFCHKCEGLCPKECKVGTKTIDSVQAAQDLVGCTHVEGSLILNLRRGYNLEPELQRSLGLVETITGFLKIKHSFALVSLSFFKNLKLIRGDTMVDGNYTLYVLDNQNLQQLGPWVSAGLTIPVGKIYFAFNPRLCLEHIYRLEEVTGTRGRQNKAEINPRTNGDRAACQTRTLRFVSNVTEADRILLRWERYEPLEARDLLSFIVYYKESPFQNATEHVGPDACGSQSWNLLDVELPLSRTQEPGVILAPLKPWTQYAVFVRAITLTTAEDSPHQGAQSPIVYLWTLPAAPTVPQDVISSSNSSSHLLVRWKPPTQRNGNITYYLVLWQRLAEDGDLYLNDYCHRGLRLPTSNHDPRFDREDGDLEAELELGCCPCQHAPPGQVLPALEAQEASFQKKFENFLHNAITIPKPPWKVTSIHRNLQRDAGRHRRAIGSPRPGGNSSDFEIQEDKVPRERAVLGGLRHFTEYRIDIHACNHAAHIVGCSAATFVFARTMPRREADDIPGKLSWEAASKSSVLLRWFEPPDPNGLILKYEIKYRRLGEEATVLCVSRLRYAKVGGVQLALLPPGNYSARVRATSLAGNGSWTDSVAFYIPGPEEEDSGGLHILLTVTPAGLMLLIILAALGFFYSRKRNGTLYTSVNPEYLSASDMYIPDEWEVPREQISIIRELGQGSFGMVYEGVAKGLEAGEESTPVALKTVNELASPRERIEFLKEASVMKAFQCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGIPRPALGDMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEELEDCPHQLQELMSSCWQQNPRLRPTFTQILNSIQKELRPSFRLLSFYHSPECQGGCGLQPTTDAESSSPPTSKGASDCSLQNGGPEH

Insrr

Insulin receptor-related protein

1300 amino acids

Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.

Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.

144.875 kDa

MAVPALWPWGVHLLMSLLSLGSGLDTLEVCPSLDIRSEVTELRRLENCSVVEGHLQILLMFAATGEDFRGLSFPRLTQVTDYLLLFRVYGLESLRDLFPNLTVIRGTRLFLGYALIIFEMPHLRDVGLPSLGAVLRGAVRVEKNQELCHLSTIDWGLLQPAPGTNHIVGNKLGEECADVCPGVLGAAGEPCSRTTFSGRTDYRCWTSSHCQKVCPCPRGMACTAGGDCCHSECLGGCSQPEDPRACVACRHLYFQGVCLRACPPGTYQYESWRCVTAELCAHLREVPGLATTFGIYEGSCLAQCPPGFTRNGSSIFCHKCEGLCPKECKVGTKTIDSVQATQDLVGCTHVEGNLILNLRQGYNLEPELQRNLGLVETITGFLKIKHSFALVTLGFFKNLKLIRGDSMVDGNYTLYVLDNQNLQQLGSWVTAGLTIPVGKIYFAFNPRLCLEHIYQLEEVTGTRGRQSKAEINPRTNGDRAACQTRTLRFVFNLTEEDRILLRWERYEPLEARDLLSFIVYYKESPFQNATEHVGPDACGTQSWNLLDVELPLSRTQEPGVTLAPLKPWTQYAVFVRAITLTTAEDSPHQGAQSPIVYLRTLPAAPTVPQDVISTSNSSSHLLVRWKPPVQRNGNITYYLVLWQRLAEDGDLYINDYCHRGLRLPTSSHDTRFDREDPALEAEPEQGCCPCQHSPPGQALPALEAQEVTFQKKFENFLHHAITIPKAPWKVTSINKNPQRDSERHRREAGLLRLGKNNSDFEIQEDKVPRERAILSGLRHFTEYRIDIHACNHAAHTVGCSAATFVFARTMPHREADGIPGKVAWKAAGKSSVTLHWLEPPDPNGLILKYEIKYRRLGEEATVLCVSRLRYAKVGGVHLALLPPGNYSAKVRATSLAGNGSWTDGVTFYITDLEEEDTGGMRIFLTVTPVGFMLLVTLAALGFFYSRKRNSTLYTSVNPEYFSASHMYVPDEWEVPREQIAIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASARERVEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLPQPALSDMIQMAGEIADGMAYLAAKKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEELENCPIQLQELMRLCWQHSPRLRPTFVHILDRIQDELRPSFRLCSFYYSPECQRGQASLLPTEAEPDSPPTLNGASDYSAPNGGPGH

Insrr

Insulin receptor-related protein

1300 amino acids

Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.

Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.

144.846 kDa

MAVPALWPWGVYLLMSLLSLGSCLDTLEVCPSLDIRSEVTELRRLENCSVVEGHLQILLMFAATGEDFRGLSFPRLTQVTDYLLLFRVYGLESLRDLFPNLAVIRGARLFLGYALIIFEMPHLRDIGLPSLGAVLRGAVRVEKNQELCHLSTIDWGLLQPAPGANHIVGNKLGEECADVCPGVLGAAGEPCVRTTFGGHTDYRCWTSSHCQRVCPCPRGLACTVGGECCHSECLGGCSQPEDPRACVACRHLYFQGVCLPTCPPGTYQYESWRCVTAELCGHLREVPGHATAFGIYEGSCLAQCPPGFTRNGSSIFCHKCEGLCPKECKVGTKTIDSVQATQDLVGCTHVEGSLILNLRQGYNLEPELQRNLGLVETITGFLKIKHSFALVTLGFFKNLKLIRGDSMVDGNYTLYVLDNQNLQQLGSWVAAGLTIPVGKIYFAFNPRLCLEHIYQLEEVTGTRGRQSKAEINPRTNGDRAACQTRTLRFVFNLTEEDRILLRWERYEPLEARDLLSFIVYYKESPFQNATEHVGPDACGTQSWNLLDVELPLSRTQEPGVTLAPLKPWTQYAVFVRAITLTTAEDSPHQGAQSPIVYLRTLPAAPTVPQDVISTSNSSSHLLVRWKPPVQRNGNITYYLVLWQRLAEDGDLYINDYCHRGLRLPTSSHDTRFDREDPALEAEPEQGCCPCQHSPPGQALPALEAQEVTFQKKFENFLHHAITIPKAPWKVTSINKNPQRDSERHRRETGLLRLGKNNSDFEIHEDKVPRERAVLSGLRHFTEYRIDIHACNHAAHTVGCSAATFVFARTMPHREADGIPGKVVWKAVGKSSVILHWLEPPDPNGLILKYEIKYRRLGEEATVLCVSRLRYAKVGGVHLALLPPGNYSAKVRATSLAGNGSWTDGVAFYITGPEEEDTGGLRILLTVTPVGFMLLVMLAALGFFYSKKRNSTLYTSVNPEYFSASHMYVPDEWEVPREQIAIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASARERVEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLPQPALSDMIQMAGEIADGMAYLAAKKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEEQEDCPIQLQELMRRCWQHTPRLRPTFVHILDRIQDELRPSFRLCSFYYSPECQRGQASLLPTEAEPDSPPTLNGASDYGPPNGDPGH

INSRR

Insulin receptor-related protein

1297 amino acids

Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.

Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.

143.72 kDa

MAVPSLWPWGACLPVIFLSLGFGLDTVEVCPSLDIRSEVAELRQLENCSVVEGHLQILLMFTATGEDFRGLSFPRLTQVTDYLLLFRVYGLESLRDLFPNLAVIRGTRLFLGYALVIFEMPHLRDVALPALGAVLRGAVRVEKNQELCHLSTIDWGLLQPAPGANHIVGNKLGEECADVCPGVLGAAGEPCAKTTFSGHTDYRCWTSSHCQRVCPCPHGMACTARGECCHTECLGGCSQPEDPRACVACRHLYFQGACLWACPPGTYQYESWRCVTAERCASLHSVPGRASTFGIHQGSCLAQCPSGFTRNSSSIFCHKCEGLCPKECKVGTKTIDSIQAAQDLVGCTHVEGSLILNLRQGYNLEPQLQHSLGLVETITGFLKIKHSFALVSLGFFKNLKLIRGDAMVDGNYTLYVLDNQNLQQLGSWVAAGLTIPVGKIYFAFNPRLCLEHIYRLEEVTGTRGRQNKAEINPRTNGDRAACQTRTLRFVSNVTEADRILLRWERYEPLEARDLLSFIVYYKESPFQNATEHVGPDACGTQSWNLLDVELPLSRTQEPGVTLASLKPWTQYAVFVRAITLTTEEDSPHQGAQSPIVYLRTLPAAPTVPQDVISTSNSSSHLLVRWKPPTQRNGNLTYYLVLWQRLAEDGDLYLNDYCHRGLRLPTSNNDPRFDGEDGDPEAEMESDCCPCQHPPPGQVLPPLEAQEASFQKKFENFLHNAITIPISPWKVTSINKSPQRDSGRHRRAAGPLRLGGNSSDFEIQEDKVPRERAVLSGLRHFTEYRIDIHACNHAAHTVGCSAATFVFARTMPHREADGIPGKVAWEASSKNSVLLRWLEPPDPNGLILKYEIKYRRLGEEATVLCVSRLRYAKFGGVHLALLPPGNYSARVRATSLAGNGSWTDSVAFYILGPEEEDAGGLHVLLTATPVGLTLLIVLAALGFFYGKKRNRTLYASVNPEYFSASDMYVPDEWEVPREQISIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASPRECIEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLPQPALGEMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEELEGCPLQLQELMSRCWQPNPRLRPSFTHILDSIQEELRPSFRLLSFYYSPECRGARGSLPTTDAEPDSSPTPRDCSPQNGGPGH