INO80

Gene

INO80

Protein

Chromatin-remodeling ATPase INO80

Organism

Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)

Length

1944 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

218.298 kDa

Sequence

MEPSKFHSTVLARPPGMYDEDDDHRRRQRDILNPPAPSQTGPGSGGSSSAGGPRPPFSLRSPTQSEFHHQSSQHHYSASSAASGPQSTYNGANNGVPQSHSHSRSNSHSRHSSSSVLHSPYQQASTASRPAHALDLHRSPQTSGLQAPQRSPGLHAPSVYYSQESREHHPPPPKPIDKPASSGRSFYDPLTDTTTTSTSDRERRTSDAGSSWHNATTNAVSTPTHRDAYNSYSKPAANPSPYYGNGKYTSPSASIYPPRSPASHPQSVATAAAEPISPPTRPPRMATPNILNPTTTSSMAAMSQAESPAQKAAVPAATPSRAAELMSFSNILSSSEPAPKPRPRSPVLAETPNKQPEPEPEREPTKEPSKEPSKEPSKEPSKEPSPPPADMDETSDSPACPEKPAEVDAETEPDAEIHDDVDTVDGLEESEKPEPPIKREKSAKVEKAPRRPRVVEKEKKERVTKAPRKSAGAKGRASEVKAESTPKQSRRSSGKQEALSSSRVPAKRQANGLTKQKAQALEQEKAVVAEMEQLEEEALDESEARAELRAFKKRKLNRQKALETTDLSVATELLPSLKDEAINRHHRRHDFSAEMVLKLGVHVALGRLRFGDHNYDAALKEVREQELFAEKERKKDMQRKRRREKSMAVTIEQKEAALAKAHATEDKLERQKLLREAERANKKAQQTKLILQKGIKGPARNIMPMDVNLEGGSMATFSADSMEPGKGKGKGRAGNRPKKSKEQKQAEKEAAEAAQAALDAGQELPSKEENPKIRIKVNKGKLSKDKDRDVDVDTIDGDNTEIKDTEEPPPKKKGKVVEEVKDTLETRFQSKGYNQIYDQIWRDMARKDVSKVYRLATDSYYTKASNLKKTAILAAKEAKRWQLRTNKGMKDLQARGKRVMRDMMTFWKRNEREERDLRKAAERQELENARKEEADREAARQKRKLNFLISQTELYSHFIGKKIKTDEVERSTDRPEVAAEEQKNKPAGENALTVKEPTGPVGAKVTNFENLDFDAEDDETLQAAAMANAQNAIAEAQRKARNFNNDDEPDEDGEMNFQNPTGLGDVEIEQPKLLTATLKEYQLKGLNWLVNLYEQGINGILADEMGLGKTIQSISVMAYLAEHHDIWGPFLVVAPASTLHNWEQEIKRFVPDLKIVPYWGSASDRKILRKFWDRKHSTYKRDAQFHVAITSYQMVVSDVAYFQKMKWQYMILDEAQAIKSSQSSRWKCLLSFHCRNRLLLTGTPIQNNMQELWALLHFIMPSLFDSHEEFSDWFSKDIESHAQSNSKLNEDQLKRLHMILKPFMLRRVKKHVQKELGDKIELDVYCDLTYRQRAYYANLRNQISIMDLIEKATLGDDNDSGTLMNLVMQFRKVCNHPDLFERADTSSPLALVRFAETGSFAREGNDVTVGYTTRSVVEYILPRLLWRDGGRLTKAGSDNPSAGFRSRYLGEMMNIWSSTNIRESVDGTDNFSFLRFADTSIAEAEKVGKTDLFARASELAQRRNRLANMHVSYDDDEEDNFTPAHALFLIRQRQDRTALSEITSEGALQNLMNVSHVMYEDANLPRMDQAARPGASAPPIEVVCHTSSTQIERDRVLFNVPMRKALFGPNLDEQKEFVLQKVPVEQLPPAPLLPKPDNERQRFTSITVPSMRQFITNSGKLAKLDELLFKLKAGGHRVLLYFQMTRMIDLMEEYLTYRNWKYCRLDGSTKFEDRRDTVHDFQTNPSIFVFLLSTRAGGLGINLTSADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLITRGTIEERIRKRAMQKEEVQRVVITGGAGASSGVDFSGRRAPENRNRDIAMWLADDDQAELIERRERELLESGELDKVAKKRGGGKRKKVAKDMGDGGGVSLDEMYHEGEGNFDDNKLSGAATPNVPDSTDAKPGKKKKATGKKAKTTKQRLAIADGQMDM

Gene

INO80

Protein

Chromatin-remodeling ATPase INO80

Organism

Ustilago maydis (strain 521 / FGSC 9021)

Length

1910 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

214.514 kDa

Sequence

MSGEDRGAPYRYAGERPPAYPADGYASYQRGLKSSIPSRSYDTAYPEQGYDRHLRERVHPAYTTGPSYGVPPPPPTDYRRPPPQAAYRYEEDYHHRRAPAQPHLEYAPEHRRQPVHSDAYREADDRRSFEQARSDPYASPSRHAYQDSYRSELPHERRHAPAAYERISVRDDARSAPENRHIDEPAVYRRDEYDAHSREIQPSYRRGAHRSPRLSPQPVVSAHERSSEYATRDYSASAARYAEPVHQPESPPRPSMSIFNMLNDRSANGAVESVHSSPTKSSIAAEHESYPTTAQEPSHASRAAFDPAREQSYSTARDSQAYSRGSEARAGAARVNYTVHPEDEAAISQRRNSSAHQQSSIKSVRHPANAVDEPLIRVKHEEATSASLDAQMSAEPPVSHTLNNGERLSAQDAKVATEDSSLAANGNGKVDSAGGTARPAPAKTQLKLRNNPLPASKSNSSFVAPPPPAKKNRDPDGWESDLSNEENQPFWQTELDDYIFDVRERQRLIEDAFVASMREKHVEVERRLARAYEGRYFAVIRQIRLREQQEASQRDMERRQDHVRQQRDHEIDLELLGTLSDGQQNMGTRKKKGGRGTDDDGLLQADDDDDDDSDDVALADLAARNGSKSNIIKLKRSKGKPAAADPRNKKRRLENGAALSPAPGSEVDSTLADFGGNFDGDDSAFASHQASPTPDDVSFALDVDASGKVPIDARRAQQLEDAHRRIWTTIAKRDVPKVYRTVLQSASSKTMYWRRISSVVQREAKRGAARNNKTVKDVQLRARKVMREVLVFWKRNEKEERELRKKAEREALEKAKKEEEMREAKRQARKLNFLISQTELYSHFVGSKLKTAEAEESEETAGSSKIIDPNAQPSDATVLPINPHSELADAEARLAELDDIDFDDEDESNLRAHAARNAQEAVRLAKEKAQAFDVAAAEERRRNEAAAREREGLDAGPVKQIEEKDLGKAFDSDDMNFLNPTSMGQTEIKQPKMLTCQLKEYQLKGLNWLANLYEQGINGILADEMGLGKTVQSISLMAYLAEVHDIWGPFLVIAPASTLHNWQQEISKFVPTLKALPYWGNVKDRAVLRKFWNRKQISYNRDAPFHVLVTSYQLVVSDEKYFQRVKWQYMILDEAQAIKSSSSIRWKTLLGFNCRNRLLLTGTPVQNSMQELWALLHFIMPSLFDSHDEFSEWFSKDIESHAEQKGTLNEHQLRRLHMILKPFMLRRIKKNVQNELGDKIEIDVFCDLSARQKMLYRGLRANISVAELMDRATSNDEAGLKSLMNLVMQFRKVCNHPELFERADVRAPFALADFARSGSLAREGDLLNLPDSTTSLIELQVPKLLVREGGIFDIPGHNSRKGFDTGYLQNLFNIWRAPHIHESLQEERSTFASLPLIGVSPSEAQKTFHSTGIKRILAAAAEERHWRSLEAFASDDTFAAASVRPLAKMLRPMPTTSGRSPSVLMPLEEVAADYRRHSYLAKDSARAVVAPAVAPPIKLYSNDGPFMQAQERFSRDAQVSVTLFGLSPEGRESVKRVEELQSELPEVPPQGVMRDSSIDQLPYNGMQVPQMNKLIVDSSKLAKLDVLLRELKANGHRVLIYFQMTRMIDLMEEYLIYRQYKYLRLDGASKISDRRDMVTDWQTKPELFIFLLSTRAGGLGINLTAADTVIFYDHDWNPSNDSQAMDRAHRLGQTKQVTVYRLITKGTIDERIVRLARNKKEVQDIVVGTKAYSETGMAKPQEIVSLLLDDDELAESMLRKKQAEEAQTAQEKADLARASHAKRRLNKDRAAAAVESPAPVGSTWSLEDDEDDFFGARPPSKADTDTAETTPQLQSKKRSVGGGGGGSGGAKRGRISEVASPRMTPLSLDDGALMASGEQLASPSKGAAAKRKSKSHRKKTVDELAGVDLD

Gene

INO80

Protein

Chromatin-remodeling ATPase INO80

Organism

Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084)

Length

1904 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

215.076 kDa

Sequence

MDQNGYNSSALQRPPRRGDEGCEEDRDSRPHHHHRHHHHHHHHRRDGDLPAGAVAGEAATASSNAGGANAHQHSTFSLRSPKPEYRPPPFSSPNGHNHSHHNTSTSSANHSLQSPPRPALPNPYMSSSTGAPGGPVAPALPPPVGINSSSSPGSSAAGLHQRHHQPGAPAHQHRAAPPPVSPLHPPVAYYPPGTNTDIYIPPPEPKPASRGFYDPTTDTTKERRISDAATPGASWHNANANAPPAGTPKTRDPYSYSQTADQHTPSYYNGGSYTSPRGPSYNRPRSPLSHSHQNPPAGSLSPPGQQPLLASPSVRHGTTANMNPTTNGASAIPPFKSDLAAPSPPKPAPSSTTSRANPMSFDSILSSSEPAPKPKEPSPIIAREPEIKEEREPRRDRESKRDSREPKQTKRSLEPELDHDTEVEKDVETEPEPLPSREKEKEPAPKKRGARKSTKGRASDIRDAATPKNGRRLSVKKESPTPRLPAKRQANGQPKPKTWSAEMEKKIQNAESDIENRAANLDADEFDEQQYKERAQKRRRVMSELDVEYGLSRRDALANTISKKLVLHAELGKRRYDDVFYDEALHEVREQEVYAEKERKKDMQRKRRREKSMAVTMEQKEAALARAEAAEDETERQKHLRDAERASKKAQQTKLILQKGIKGPARNLEINLEGGTMSSFQASDVESGEAGTPSGKRKGKGRSGPRLKKSKEQKQAEKDSAEAAQAALDAGEELPTKEENRVRIKIKKTKKDVAVDSEKDKDEAEKTEEEVVEKKTKKSKDKDKEKVDDIPDNEKRFMSKGYNQIYDQIWRDMARKDVNKTFKLAVDSYATKASNLKKTAILASKEAKRWQLRTNKGTKDLQARAKRVMRDMMGFWKRNEREERDLRKAAEKQEIENARKEEADREAARQKRKLNFLISQTELYSHFIGKKIKTDEVERSTDNPEIAKDAHQTDQKMLDIDEPTGPVIGKVTNFENLDFEEGSDEALRAAAMANAQNAIAEAQKKARDFNNQGLDMDDEGEMNFQNPTGLGDVEIEQPKLINAQLKEYQLKGLNWLVNLYEQGINGILADEMGLGKTVQSISVMAYLAEKHDIWGPFLVVAPASTLHNWQQEIAKFVPEFKILPYWGGASDRKVLRKFWDRKHTTYRKDAPFHVCVTSYQLVVSDVAYFQKMRWQYMILDEAQAIKSSQSSRWKALLNFHCRNRLLLTGTPIQNNMQELWALLHFIMPSLFDSHDEFSEWFSKDIESHAQSNTKLNEDQLKRLHMILKPFMLRRVKKHVQKELGDKIELDIFCDLTYRQRAYYSNLRNQINIMDLVEKATMGDDQDSGTLMNLVMQFRKVCNHPDLFERAEVNSPFACAYFAETASFVREGNDVAVGYSSRNLIEYELPRLVWRDGGRVHKAGPDSQVAGWKNRTLNHLMNIWSPDNIRDSSDGSKAFSWLRFADTSPNEAYQATHQSLIARAAKELQKRDRLGYMNVAYSDTEDANFTPAHALFQIRPRQNRKPLADITNEGILSRLMNVAQGDYDESGLGRLEPAGRPRASAPPIQVSCRSWASEFERSEVLFNAPIRKILYGPTVFEEKALVEKKLPMELWPTRQMLPKPDHEKKGFTNISIPSMQRFVTDSGKLAKLDDLLFKLKSEGHRVLLYFQMTRMIDMMEEYLTYRNYKYCRLDGSTKLEDRRDTVHDFQTRPEIFIFLLSTRAGGLGINLTTADTVIFYDSDWNPTIDSQAMDRAHRLGQTKQVTVYRLITRGTIEERIRKRAMQKEEVQRVVIQGGGASVDFSGRRAPENRNRDIAMWLADDEQAEMIERREKELLESGELEKQQKKKGGKRRKAENSASLDEMYHEGEGNFDDGSKGVSGTATPATAATPADSDSKGKKGRKGTKRAKTAKQRLAIADGMME

Gene

INO80

Protein

Chromatin-remodeling ATPase INO80

Organism

Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)

Length

1765 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

196.403 kDa

Sequence

MGAMDDRRYSYPPPRTSYVQPSTHPSPTASDYRYRSPVLPQHPPTHHSPSSYSASLYGQPKEDPAIAYARMREEMRTAEEARREAEALEYRRKRDMEFAARRPGSELMDDPRRIPHSSFPRSQMYGPSADQSRVMPSRNGKDYISEPPSPSELYPTDEDTERLPIDRYRRDIDVPPLPRQLPPPPSEIGRMADRARSPSAPIAPPLLKVVRKRTKVIRPNDFLVGNEDVWEDGLIRYQSKREDEVRAIAQWAASCQVRNGVGEPSLPQTQDESIKVRKINGDIATPTNKKKRKSRKLNLDDELLGLASSPPGSPNAAAEAEKSESKHHIYGMNGPIDPANPPSPSTIVYPSGLTRAEVIAKCEAGDVEGLTEDDVKAVQDEMWMREKAAQAAENGGVLPTNKDGTVRRKPGPAKGWRKIRGIDKKKETTPGKAQSTTAGSVAGSVADEEAEADIAALLDDSIAKKGKKVKRRKLEEPGAESPRFADAEDEYNEHRPSDSVLLDEIEDEHSRAGSVGESNALDTLPAASAPPKKKNSKTKEPGVGKGRWTRPTKPEKELVKKAEALASRTSKASLAGPSDDTFGVGPGPAEEVQEEIKHEYAPNTHDPRGVSENEAKIRHELVEDLQKQAWSNIVRDVPRIYRVFQGYDQSMKQIAQRRAQACVRNAFGQRNQKTMQRQSGKVNKEGAAKAKRIVKELAAFWRKNEKDEVIARKKAEREALERAKAEEEARETKRQSRKLNFLLTQTELYSHFIGKKIKTKEAEAAEGMDVEEEEKRGMEEIAIGEDGEPLPDLDYDEDDEENLRKHAARGAQAAIQAARDKARAFDDSIVGRGAPLPGDDTMDGDELNFQNPSLGENSVTITQPKMLMAQLKEYQLKGLTWLGNLYEQGINGILADEMGLGKTIQSISLLAYLAEHHNLWGPFLVIAPASTLHNWQQELARFVPRLKALPYWGSPKDRETLRKIWSRKNQTFSEDSPFHILITSYQLAVQDEKYLQGMKWQYMILDEAQAIKSSSSARWKSLLSLHCRNRLLLTGTPIQNSMHELWALLHFIMPQLFDSHEEFAEWFSKDIESSSGGVTGNLKPEQLKRLHMILKPFMLRRVKKHVQKELGDKIEIDLLVDLSQRQREIYKALRQRVSITDLLATAENNTDNGNPKNMRSLVNLVMQFRKVCNHPDLFERADVVSPFVFGEFSQSGNLAREGDGMYLPDSARNAIEVQIPRILWTDGGKLDIPGEQSLAGSDTKILQNLLNIWTPEWINERTKCADAEFGFVKLVGSSPGETSRSAKSPVLVQLLEGAEKERRWTEEGRFVDDSEFAASVKKGFRVPSVIPVLTQPGQVSLREISRRVWDESYLSRDDARCIGDYAIAPIVKPIASNRSFLNAQDRILNQPLAHSTLYGLAPSELHDPLAAEQFSRIAPSVPLTGLIPSSASSQTPVSPLHIPPTKRLIVDSAKLARLDSLLRELKAGGHRVLLYFQMTKMMDLIEEYLIFRQYKYLRLDGSSPIAERRDMVTSWQTNPDIFVFCLSTRAGGLGINLTAADTVIFYDHDWNPSSDAQAMDRAHRVGQTKQVTVYRLVARGTIEERILQMARGKKDIQDVVVGTKSVSDVAKPSEIVSLFMDDEELAESVAKRKQAEAHGYIAPTIIPNGRRSQFGDGLVLDDGEGDDGFFNAAAAARANAEEEEGLGAEEESKGKGKAKAAAAVTFPVPGEKRSHKKGMGKKAQAAAAAAALERVIAGNEEPLAASKPPAKKKVKIALGPDGLPL

Protein

Chromatin-remodeling ATPase INO80: INO80

Gene

INO80

Protein

Chromatin-remodeling ATPase INO80

Organism

Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)

Length

1765 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

196.403 kDa

Sequence

Protein

Chromatin-remodeling ATPase INO80: INO80

Gene

ino80

Protein

Chromatin-remodeling ATPase INO80

Organism

Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)

Length

1708 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

192.15 kDa

Sequence

MTGAPPYNPQSPTQQPRFPVYSPPNKNRSYYPNNDQYQQHPPQTPPAFAPQPSLSRSPHYSHAPSPLPATLPPLNGGAPPPGHHSEPSSQYQAHSSAGTPQFSLPRPYSASMMSSNGASPYNHSTSSHAHPSARLESLSQSPPKKETEPLYPIGGNGAPGYSSSMMREPRPASPPRETKHARAADPMSFASILSGPTEESSPKKQPSLPEALPAPATTITPPPPALAPVPARRRLTPPPVTHGLPPTSQLKVKEPEPISPAALPRLEKKPGAEKRRRNAEQEPKSAEALPVASANGAFEPTKAARVSNRKTLTERDAETINKIIAEIDNADKSDVESPGFEAEYDGYIVKSKKRALDAEKAEGIRRKRRRHDFLVKLGKTFEKQANAGVDRFRAANEASVIAEVQAKEIQDEKERKKDMQRKRRRENTVRLEMQKKLEAERKANKANDAAEKAKFLREAERAQRKIKSTKRALEGVTSPEEIGEVTPLAPNLEGGTTSSFHIGRSSPSRRKSGRSGTSRPKKSKEQKQAEKDAAEAAYAAMENDEPLPLAPKEDPRKETLKKEAKGARSKEPTPSPVSTFESKGYNQIYEQIWRDIARKDIPKVYRIKTLSLSTRQENLRKTAQLASKQSRKWQERTNKSMKDTQARAKRTMREMMSFWKRNEREERDLRRLAEKQEIESAKKAEAEREANRQKRKLNFLISQTELYSHFIGRKIKGAGADSSGDTAVDGSDETIQPGKADHTIDLPPSVADVGTKVTNFEDLDFDAEDETALRQAAMANAQNAVKEAQERARAFNAEENPMAALDEGELNFQNPTSLGDIEISQPKMLTAKLKEYQLKGLNWLVNLYEQGINGILADEMGLGKTIQSISVMAYLAEVHNIWGPFLVIAPASTLHNWQQEITKFVPDIKVLPYWGSAKDRKVLRKFWDRKHITYTKESEFHVLVTSYQLVVLDSQYFQKVKWQYMILDEAQAIKSSQSSRWKNLLGFHCRNRLLLTGTPIQNNMQELWALLHFIMPTLFDSHDEFSEWFSKDIESHAQSNTKLNEDQLRRLHMILKPFMLRRVKKHVQQELGDKVEKDVFCDLTYRQRAYYANLRNRVSIMDLIEKAAVGDEADSTTLMNLVMQFRKVCNHPDLFERAETKSPFSVGYFAETASFVREGQNVDVRYSTRNLIEYSLPRLLCSSSGRVDMAGPGNEQAGFRGKYLQHLMNIFTPENIKRSIDEDGGFSFLRFADTSINEAYEQSHLGVFERAVRRRGQSNRLSRLNVIYDDEEDEQTSKSVLPHSLFNIVQRNDRQAVRNVTVEGYMRDLMNVSEVTFEREGLDVIEPSASPAASAPPITISCSGQVALRETQDSFFNVSVRHALFSTPSRQMEQQILEKKLDPAPFSLPPMLPKPISTKGRYTHIEVPSMRRFVTDSGKLAKLDELLRELKAGGHRVLLYFQMTRMIDLMEEYLTYRNYKYCRLDGSTKLEDRRDTVADFQQRPEIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLITRGTIEERIRKRALQKEEVQRVVISGGAAGGVDFNTRNRESRTKDIAMWLADDEQAELIEQKEKEALDRGEVFGAGKGGKKAAQKRKKDLTLDDMYHEGEGNFDDISAKPSGAATPVSTADNFGTPSSTPVPKRGRGRGTGKGSSKRAKTTTERLRLIDGDGGLES

Protein

Chromatin-remodeling ATPase INO80: ino80

Gene

ino80

Protein

Chromatin-remodeling ATPase INO80

Organism

Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)

Length

1708 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

192.291 kDa

Sequence

MTGAPPYNPQSPTQQPRFPVYSPPNKNRSYYPNNDQYQQHAPQTPPAFAPQPSLSRSPHYSHAPSPLPATLPPLNGGAPPPGHHPEPSSQYQTHSSAGTPQFSLPRPYSASMMSSNGASSYNHSTASHAHPSARLESLSQSPPKKETEPLYPIGGNGAPGYSSSMMREPRPASPPRETKHARAADPMSFASILSGPTEETSPIKQPSLPEALPGPATTITPAPPTLAPVPARRRLTPPPVTHALPPTSQLKVKEPEPISPAALPRLEKKPSAEKRRRNVEQEPKSAEALPVASTHGAFEPTKAARVSNRKTLTERDAEAINKIIAEIDNADKSDVESPGFEVEYGRYMVKSKKRALDAEKAEGIRRKRRRHDFLVKLGKTFEKQANAGVDRFRAANEASVIAEVQAKEIQDEKERKKDMQRKRRRENTVRLEMQKKLEAERKANKANDAAEKAKFLREAERAQRKIKSTKRALEGVTSPEEIGEVTPLAPNLEGGTTSSFHIGRSSPSRRKSGRSGTSRPKKSKEQKQAEKDAAEAAYAAMENDEPLPLAPKEDPRKETVKKEAKGARSKETTPAPVSAFESKGYNQIYEQIWRDIARKDIPKVYRIKTLSLSTRQENLRKTAQLASKQSRKWQERTNKSMKDTQARAKRTMREMMSFWKRNEREERDLRRLAEKQEIESAKKAEAEREANRQKRKLNFLISQTELYSHFIGRKIKGAGADSSGDTAVDGSDETIQPGKADHTIDLPPTVADVGAKVTNFEDLDFDAEDETALRQAALANAQNAVKEAQERARAFNAEENPMAALDEGELNFQNPTSLGDIEISQPKMLTAKLKEYQLKGLNWLVNLYEQGINGILADEMGLGKTIQSISVMAYLAEVHNIWGPFLVIAPASTLHNWQQEITKFVPDIKVLPYWGSAKDRKVLRKFWDRKHITYTKESEFHVLVTSYQLVVLDSQYFQKVKWQYMILDEAQAIKSSQSSRWKNLLGFHCRNRLLLTGTPIQNNMQELWALLHFIMPTLFDSHDEFSEWFSKDIESHAQSNTKLNEDQLRRLHMILKPFMLRRVKKHVQQELGDKVEKDVFCDLTYRQRAYYTNLRNRVSIMDLIEKAAVGDEADSTTLMNLVMQFRKVCNHPDLFERAETKSPFSVGYFAETASFVREGQNVDVRYSTRNLIEYNLPRLLCSPSGRIDMAGPGNEHAGFRGKYLQHLMNIFTPENIKRSIDEDGAFSFLRFADTSINEAYEQSHLGVFERAVRRRGQSNRLSHLNVIYDDEEDEKTSKFVLPHSLFNIVQRNDRQAVRNVTVEGYMRDLMNVSEATFERDGLGVIEPSASPAASAPPITISCSGQVALRETQDTFFNVSVRHALFSTPSRQMEQQILEKKLDPAPFSLPPMLPKPISTKGRYTHIEVPSMRRFVTDSGKLAKLDELLRELKAGGHRVLLYFQMTRMIDLMEEYLTYRNYKYCRLDGSTKLEDRRDTVADFQQRPEIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLITRGTIEERIRKRALQKEEVQRVVISGGAAGGVDFNTRNRESRTKDIAMWLADDEQAELIEQKEKEALDRGEVFGAGKGGKKAAQKRKKDLTLDDMYHEGEGNFDDISAKPSGAATPVSTADNFGTPSSTPVPKRGRGRGNGKGSSKRAKTTTERLRLIDGDGGLES

Protein

Chromatin-remodeling ATPase INO80: ino80

Gene

INO80

Protein

Chromatin-remodeling ATPase INO80

Organism

Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)

Length

1707 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

192.466 kDa

Sequence

MSTSSSNIPYDVGSPRQQSQTEIRSILNPSTTSTGAHPSFNQYHPPTAAPPLIPSHIPLQSTTPSTLGLSLGTPLYQSERDIGYPRDQKPTSNYYDPTSDSSERRPATAESKWSDREAKTSQRRDSYPYQQNQPPAPSTDGPMNLYNGGYKSPVNSHFPPGSPISHAHPQGRVPPLVTQSPRMPAMESPISRHNGLGGGPELQDKPVIKQEPVPASTPSRPVDPMAFSSILSSAAPEPTPKPQPTPTPIVSKPRKASRQPIPTLKPEPSSAPSSRQSSVAPAPQPPTSRVPAKRKANGETKPTPKPKPFTKDQERDIVILMSKLDGEPEDSDVEFAEEKRLYQTRSLKRKLEVEKIETSKTKQRRTDFTNKMAKRLEKHAKAGEERYREVEGDAAISKVQADEIQTEKERKKDMQRKRRREKTVQNNMEQKEIALAKAQAAQDDQERHKFLRDAQRAEKKAQQTKQILARGDKGPEIRAVSPMEPNMQGGSMSTFTAVDPDSTKKPKRGGARPRKSKEQKQAEKDSAAAAQEAIDKGESPALMPIRDAAEFKDMKPLPSKEGVTKIKLKFKAPAEPVEVKEESPSAPVDQHNTKMYHVVYDQIWKDLARKEVPKVFKLAVDSYSIRASNLKKTAILASKEAKRWQLRTNKGTKDLQARAKRVMREMMSFWKRNEREERDTRRAAEKQEIENAKKAEADREANRQKRKLNFLISQTELYSHFIGKKIKTDEVERSTDHPDVAVPDKADHAKPDHGDLPEGTAPAKVTNFEDLDFDAEDESVLKAAAMANAQNAIQEAQNKARAFNKKDDAPAMDDEGEMNFQNPAGMGDVDIEQPKMLQAQLKEYQLKGLNWLVNLYEQGINGILADEMGLGKTVQSISVMAYLAEKHGIWGPFLVVAPASTLHNWQQEITKFVPRLKVLPYWGTAADRKVLRKFWDRKHITYTEDAPFHVLVTSYQLVVSDVAYFQKMKWQYMILDEAQAIKSSQSSRWKSLLGFHCRNRLLLTGTPIQNNMQELWALLHFIMPSLFDSHDEFSEWFSKDIESHAQSNTKLNEDQLKRLHMILKPFMLRRVKKHVQKELGDKIEEDIFCDLTYRQRAYYSNLRNQISIMDLIEKATIGDDNDTGTLMNLVMQFRKVCNHPDLFERAETTSPLSFSYFAEAGSFLREGSNVTVAYSARNMIEYSLPRLIWREGGRLDLPGHDNEHAGVKAKCLESLFNVWKPENIVDSAKEDGAFSWLRFTNTSVQELSTASRKDVFARAVDLVKRPQTLGRLNIVYDEEEDKNYTPVHSMLQIVNRKDRKPLAEVTNEGYLNKLFNVAKDVWGQSGMSRMEQCGRPSATAPPIEVTCSSRGAVIERQKILFNVPMRRALFGPSPVEEKALITSKVSPLFYPPKPMLPLPTSEKQRFTNIKVPSMRRFVTDSGKLAKLDSLLTKLKEGGHRVLLYFQMTRMIDLMEEYLTYRNYKYLRLDGSTKLEDRRDTVHDFQTRPEIFIFLLSTRAGGLGINLTSADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRMITRGTIEERIRKRALQKEEVQKVVMTGGAGGGVDFNTRSKENRTKDIAMWLVDDEEAAEIERKEAEQLRYEAENPTASKKGKGKGKKGKEGGGGSLEDLYHEGEGHFDDGSNRPSGTATPIAVDASKKKGSSSRKSGGGGRSKKAKTAKERLAMADGDVDMA

Protein

Chromatin-remodeling ATPase INO80: INO80

Gene

ino80

Protein

Chromatin-remodeling ATPase INO80

Organism

Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)

Length

1707 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

191.994 kDa

Sequence

MTGGPPYNSQSPTQQPRYPVYSPPSKTRPYYPNNDQYQQHPPQTPPAFPPQPPLARSPHYSHAPSPLPATLPPLNGGAPPSHHQESSSQYQAHQSSGTPQFPLPRPYSASVLSSNGASPYNHPTPSHAHPSSGRLDSLSQSPPKKDQESLYPIGGNVASGFSSSIMLSPPCILSDSIQKPARAADPMSFASILSGPTEERPLPRKQSPLPEPAPVQTPAPAPPVLAPVPAARKATPPPPTAPVPVPAPLPEIKEPEPLPTPLPRLEKKPSAEKRRRNVDQESRASESLPVPPTNGVSEPAKVSRASNVRKTMSERDTEAINKIIAEIDNAEKSDVESPGFEAEYERYIAKGKKRALDAEKAESIRRKRRRHDFLVKLGKTFEKQANAGMDRFRVANEASVIAEVQAKEIQDEKERKKDMQRKRRRENTVRLEMQKKIEAERKANKANDAAEKAKFLREAERAQRKIKSTKRALEGVTSPEEIGEVTPLAPNLEGGTTSSFHIGRSSPSRRKSGRSGGSSRPKKSKEQKQAEKDAAEAAYAAMENDEPLPLAPKEDPRKESLKKEAKGARSKEPTPQPLSAFESKGYNQIYEQIWRDIARKDIPKVYRIKALSLSTRQENLRKTAQLASKQSRKWQERTNKSMKDTQARAKRTMREMMSFWKRNEREERDLRRLAEKQEIESAKKAEAEREANRQRRKLNFLISQTELYSHFIGRKIKGAEADASGDAAVDGSDETVRPGKAGDHTIDLPSSVADLSTKVTNFEDLDFDAEDETALRQAAMANAQNAVKEAQDRARAFNAEENPMAALDEGELNFQNPTSLGDIEISQPNMLTAKLKEYQLKGLNWLVNLYEQGINGILADEMGLGKTIQSISVMAYLAEVHNIWGPFLVIAPASTLHNWQQEITKFVPDIKVLPYWGSAKDRKVLRKFWDRKHITYTKESEFHVLVTSYQLVVLDSQYFQKVKWQYMILDEAQAIKSSQSSRWKNLLGFSCRNRLLLTGTPIQNNMQELWALLHFIMPTLFDSHDEFSEWFSKDIESHAQSNTKLNEDQLRRLHMILKPFMLRRVKKHVQQELGDKVEKDVFCDLTYRQRAYYTNLRNRVSIMDLIEKAAVGDEADSTTLMNLVMQFRKVCNHPDLFERAETKSPFSLAHFAETASFVREGQNVDVRYSTRNLIEYDLPRLLFSSSGRLDVAGPDNEKVGFQNKYLQHLMNIFTPENIKRSVEDDGAFSFLRFADTSINEAYEQSHLGVFERAVRRRGQSDRLSQLGVIYDNEGDQTANSVLPHSLFNIVERNDRQAVYDVAPEGYMRDLMTVSESSFERQGLNVIEPCASPAASAPPIFISCSGQTALRETNDTFFSVPVRHALYSTPSRQLEEQILEKKLDPAPFSLPPMLPKPLSAKGRYTHIEVPSMRRFVTDSGKLAKLDELLRELKAGGHRVLLYFQMTRMIDLMEEYLTYRNYKYCRLDGSTKLEDRRDTVADFQQRPDIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLITRGTIEERIRKRALQKEEVQRVVISGGAAGGVDFNTRNRESRTKDIAMWLADDEQAELIEQKEKEALDRGEVFGAGKGGKKAALKRKKDLTLDDMYHEGEGNFDDISAKPSGAATPVSTADNIATPSSTPVPKRGRGRGTVKGSSKRAKTTTERLRLIDGDGGL

Protein

Chromatin-remodeling ATPase INO80: ino80

Gene

ino80

Protein

Chromatin-remodeling ATPase INO80

Organism

Aspergillus niger (strain CBS 513.88 / FGSC A1513)

Length

1697 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

190.332 kDa

Sequence

MTGAPPYNPQSPTQQSRYPVYSPPAKSRPYYANNEQYQQHPPQTPPAFSSRSPHFSHAPSPLPGTLPPLNGAAPPSSHPSEPPSQYQAHSSAGNPQFALPRPYPGSVLSGNGASPYGHSTPSHAHPAGRPDSHPQTSPKKESESQFPMSTHGVMGYPSSVVREPRASSPPKDVKPTRAADPMSFASILSGPTEERAPPPRQSSAEATPTPLAPAATAQTSLSPPPVASAATSQKSKDRAPALTASLPRLEKKPTTEKRRRNPPETEQKTADSRTSNVANGVSEPSKTLAQPRGAGSRPVMSERETEALNKALADMAEADKSDVEAPGYDRFREEYRAKGKKRAFATEQAEILRRKRRRNDFLVKLSKSLEKQATAGMDRFRYANEASVVAEVQAKEIQDEKERKKDMQRKRRRENTVRMEMQKKKEAEAKAHEAQDSAEKAKFLREAERAQRKIKTTKRALEGITAPEEISEVTPLAPNLEGGTTSSFHIGRGSPSRRKSGRGGPVTRPKKSKEQKQAEKDAAEAAYAAMENDEPLPIAPKEDPRKESLKKEVKGGRSKEPTPTPLSAYETKGYNQIYEQIWRDIARKDIPKVYRIKALSLSTRQENLRKTAQLASKQSRKWQERTNKSMKDTQARAKRTMREMMSFWKRNEREERDLRRLAEKQEIESAKKAEAEREANRQRRKLNFLISQTELYSHFIGRKIKGAEGDAAGDTAVEATGETVQPGKGQDHTIDMPSSVADAGTKVTNFEDLDFDAEDETALRQAAMANAQNAVQEAQDRARAFNSGQNQMDALDEGELNFQNPTSLGDIEISQPNMLTAKLKEYQLKGLNWLVNLYEQGINGILADEMGLGKTIQSISVMAYLAEVHNIWGPFLVIAPASTLHNWQQEITKFVPDIKVLPYWGSAKDRKILRKFWDRKHITYTKESEFHVLVTSYQLVVLDAQYFQKVKWQYMILDEAQAIKSSQSSRWKNLLGFHCRNRLLLTGTPIQNNMQELWALLHFIMPTLFDSHDEFSEWFSKDIESHAQSNTKLNEDQLRRLHMILKPFMLRRVKKHVQQELGDKVEKDIFCDLTYRQRAYYTNLRNRVSIMDLIEKAAVGDEADSTTLMNLVMQFRKVCNHPDLFERAETKSPFSTAYFAETASFVREGNNVDVRYSTRNLIEYPMPRLLCGAGGRVDVAGAENPHAGFRGRYLNHLMNIFTPENMKQSIQDDGAFSFLRFVDTSLGEAYEQSHLGIFERAVRRRGQVNRLSRLNVAYDDDKELAGSALPHTLFNIVDRNDKHAVNEVAAEGIMRDLMTVSQSTYEREGLNIIEPCVSPAASAPPISVVSSSHIPSIETRDTLFNVSVRHALYSTPSRQVDEQIIEKKVDPTPYSLAPMLPKPISAKGRYTHIEVPSMRRFVTDSGKLAKLDELLRELKAGGHRVLLYFQMTRMIDLMEEYLTYRNYKYCRLDGSTKLEDRRDTVADFQQRPEIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLITRGTIEERIRKRALQKEEVQRVVITGGAAGGVDFNTRNRESRTKDIAMWLADDEQAELIEQKEKEALDRGEVFGAGKGGKKAAQKRKKDITLDDMYHEGEGNFDDASAKPSGAATPVSTAENVGTPSSTPAPKRGRGRGSGKGTSKRAKTTKERLRLIDGDGGLGPS

Protein

Chromatin-remodeling ATPase INO80: ino80

Gene

ino80

Protein

Chromatin-remodeling ATPase INO80

Organism

Aspergillus terreus (strain NIH 2624 / FGSC A1156)

Length

1690 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

189.823 kDa

Sequence

MSGAPPYNPQSPTQQSRYPVYSPPNKNRPFYSNNDQYQQHPPHTPPAYPSQPAAMSRSPHHPHAQSPLPGTLPPLNGAAPPPHHPDASSQFQPHAAAGTPQYSLPRPYSGSVLSSNGTTPYGPSTASHAHPSARPDGPPHLSPKKEMEPSFSMGSHGVPGYPPSAMREPRLASPPKEVKPARAADPMSFASILSGPTEDRPPPRKPSPPEVAPAPLALAPASAARQSPPLPISARAPPLSKEPEPAPVTPLPRLEKKPSSEKRRRNVDQEPKMGELSVPPTNGLLDPAKAAVQPRAPPRKTLSERETEYINRVMAELDSMEKSDVESPGFEWELERYTAKGKKRAMDAERAESVRRKRRRHDFLIKLGKTFEKQASAGMDRFRMANESSVVAEVQAKEVQDEKERKKDMQRKRRRENTVRLEMQKKLEAERKANKAQDSAEKAKFLREAERAQRKIKTTKRALEGVTAPEEIGEVTPLAPNLEGGTTSSFHIGRSPSRRKSGRGGPVTRPKKSKEQKQAEKDAAEAAYAALENEELLPLAPRDDRKDVLRKDGKGVLSKEATPIPLSSYESKGYNQIYEQIWRDIARKDIPKVYRIKVLSLSTRQENLRKTAQLASKQSRKWQERTNKSMKDTQARAKRTMREMMSFWKRNEREERDLRRLAEKQEIESAKKAEAEREANRQRRKLNFLISQTELYSHFIGRKIKGAEGDESGDTAVEGANEAAQSKMDVPAGALKAGAGVTNFEDLDFDAEDETALQQAAMANAQNAVQQAQDRARAFNNTKDDPMAAMDEGELNFQNPTSLGDIEISQPSMLTAKLKEYQLKGLNWLVNLYEQGINGILADEMGLGKTIQSISVMAYLAEVHNIWGPFLVIAPASTLHNWQQEITKFVPDIKVLPYWGSAKDRKILRKFWDRKHITYTKESEFHVLVTSYQLVVLDAQYFQKVKWQYMILDEAQAIKSSQSSRWKNLLGFHCRNRLLLTGTPIQNNMQELWALLHFIMPTLFDSHDEFSEWFSKDIESHAQSNTKLNEDQLKRLHMILKPFMLRRVKKHVQQELGDKVEKDVFCDLTYRQRAYYTGLRDRVSIMDLIEKAAVGDEADSTTLMNLVMQFRKVCNHPDLFERAETKSPLTTAYFAETASFVREGQFVDVGYSTRSLIEYPLPRLLCSSAGRVDVAGPDNLHAGFRGKYLAHMMNVFAPENIKQSIQEDGAFSFLRFIDTSMGDAYEQSHRGVFERALSRRGQPNRLSRLNVVYEEDEGDAPLAHTMLNIVARNDQSAVHEITPDGYMRELMTVSQSTFEREGLNVIEPCASPAASAPPVTITSSSPAAQIEMSDALFNVPVRHALFSTPTRQLEEQILEKKLDPVPYSHPPMLPKPTSLKGRYTHIEVPSMRRFVTDSGKLAKLDELLRELKAGGHRVLLYFQMTRMIDLMEEYLTYRNYKYCRLDGSTKLEDRRDTVADFQQRPEIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLITRGTIEERIRKRALQKEEVQRVVITGGAAGGVDFNTRNRESRTKDIAMWLADDEQAELIEQKEKEALDRGEVFGASKGGKKAAQKRKRDITLDDMYHEGEGNFDDASAKPSGAATPVSTADVGGTPSSTPVPKRGRGRGTGKGTSKRAKTTKERLRLIDGDGGLGPM

Protein

Chromatin-remodeling ATPase INO80: ino80

Gene

INO80

Protein

Chromatin-remodeling ATPase INO80

Organism

Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)

Length

1673 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

188.809 kDa

Sequence

MFRDPVLRRSVDGEGETMQQGDHQAHSPTQTQGHQPRIHSATNYPPHQQSRPPPSPSHTTELPPISTALHSRDTSASKYYDPTSDHGERGLARDTARYDPQHSPQTRETHTYSDARPAHSPYEKPYQSPIASSYAHQSPLQRPLSQHHHTGGMEAMSHSPVSPSVYHANRGAVQPPPANYARRPSMKDEARENRPFPLQHHLLTVTQAPPPTRADPMSLSSIMSAGTDSDPPAKAQPPASLNHDHGHLSKPPNAHFVKQEPMASPAPADLAPHDNGILHRAPYDPIHPVAPSHALQSFATPRDLPAPDEAEIEAALAHIETKQMNDLDGPGAPFEHEEWRERSLKRGLDVISGETVKRKKRRHATLTRYHDVLAAHRDYAKHSYNLEHEGDAWQQVQSQEIAEEKERKKDMQRKRRREKTIQNEEAKRAEALAKAGQADNEEEKERHLAAAQKAERKAKNTSQLLQGNAPSKDIREVTPHGPNLEGGTMSSFQASDDLGTGGKRKGNRGTGRLKKSKEQKQAEKDAAAAGQAAIDRGDDLPSIAPREEARLGSLRDRSYTEELGNGFVTSHDSSAYRNLYAQIIKDLARKDVPKVVRIKENSLSTKQSNLRKTAQLAAKEARRWQMRTNKNQKDTQARAKRGMREMLAFWKRNERDERESRKNAERQELENAKKVEAEREANRQKRKLNFLISQTELYSHFIGKKARTAEIERSTDDAETAASAPAEAEKPGIDVDGMDGNPTAKVTNFEDLDFDNDDESALNAAAMANAQHAIQEAQDRARAFNNPEGQEDDGELNFQNPSGLQNKEDWIPQPKLLNCTLKEYQLKGLNWLVNLYEQGINGILADEMGLGKTVQSISVMAYLAERYNIWGPFLVIAPASTLHNWQQEIAKFVPDLNVIPYWGTAKDRKVLRKLWDRKHVTYTRDSPFHVVVSSYQLVVQDAQYFQKMRWQYMILDEAQAIKSSNSSRWKSLLNFHSRNRLLLTGTPIQNNMQELWALLHFIMPSLFDSHDEFSEWFSKDIESHAQSNTKLNEDQLRRLHMILKPFMLRRVKKHVQKELGDKIELDVYCDLTYRQRAYYANLRNKISIMDLIEKAVGDEQDSATLMNLVMQFRKVCNHPDLFERADTWSPFTFASFAETPSFLREGQNVRVAYTTRNFIEYSLPRLIGRNGGRLEIAGPDNEKAGFRGHYLDNLFNIWSPHNMEQSAREADAHSWLRFSDLSATEVSKIAKSDLFERALETGSSPNKLGQYETLYDDENDKYEPKHSMLRIIDRKDRAPLTDLTSEGYMRNLMNVSQSAFERTGLDVIEPCAKPAAAAPPVELYCASQDVIAEKQRVFFNPAIRNALYGVSDKTEQVLLDTKSHSTALVRNTLPSPTNARTRYTHIEAPSMSRFVTDSGKLARLDALLKGLKAGDHRVLLYFQMTRMIDLMEEYLTYRNYKYCRLDGSTKLEDRRDTVADFQSDPTIFVFLLSTRAGGLGINLTSADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLITSGTIEERIRKRALQKEEVQRVVISGGAGGAVDFNTRSRENRTKDMAMWLVDDEQAAEIEKKEAELAEAEKNAPPGKKRSKKKRVEANLDDMYHEGEGHFDESAKGSGAATPVPGTEGAPGAPGGKKGKKGLSKKAKTAKQRLAVADGEV

Protein

Chromatin-remodeling ATPase INO80: INO80

Gene

INO80

Protein

Chromatin-remodeling ATPase INO80

Organism

Coccidioides immitis (strain RS)

Length

1662 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

187.85 kDa

Sequence

MAGVPPYGMHSPTQQPRYPSYSPSTRDRQPYSGNDPYQHPPRTPPSFAPPSSLSRSPHFARPPSPMNTTLPPLNGTVVNADGSPPYHGHSGSATSGYTLPRPFGGSLMSATSHSPPPSYSHASGSHSHPSNIPDSFSQSPKRESEPYDVRSDRTGPVSQTPARPASPKESKSARSNPMSFANILSGPADEPPPRRSSPPPQTYKSSTLPPIAPTPKVDKEPLSEPEKRRGSSHYETAYNEMPHRPAMNGFTPAKSPLAAMPSPLSKSRKLVDEEEIDKISRENIARALEQIDALDNSDVEAPGFEQEWERYMAKSRKRARELDAIEGRKRKRRRTEFLGKLAKMFEKQALQGIERFNRIHEAEVQMEVQQKEIQEEKERKKDMQRKRRRENTVRHEMEKLNAAQKKANKIEDEAEKQKLAKEIARSKKKIKDTTLALERGEASQEISEVNPLAPNLEGGTTSSFHIRTKSPPPPKKRAAKGTSSRPRKSKEKKQAEKDAAEAAYAAMENEDLVPLAPKEDPRKTSLKKESKAARSKEPSPVPATPYDSKGYNQFYEQLWRDIARKDIPKVYRIKVVSLSTRQENLRKTAQLAAKQARKWQEKTNRSMKDTQARAKRTMREMMTFWRRNEREERDMRRLAQRQELELAKKAEADREANRQRRKLNFLISQTELYSHFIGRKIKTDKAQDSGDATTTAAIEGNGEGKVPDSLVPLPDGGAKVTSFDDLDFDAEDETALRQAAMANAQSAVQEAQDRARAFNGEENKMADFDEGEMNFQNPTSLGDVEVSQPKMLTCQLKEYQLKGLNWLVNLYEQGINGILADEMGLGKTVQSISVMAYLAEVHDIWGPFLVVAPSSTLHNWQQEIVKFVPDLKVLPYWGSAKDRKVLRKFWDRRNITYRKQSEFHVLVTSYQLVVGDAQYFQKIKWQYMILDEAQAIKSSQSSRWKSLLGMHCRNRLLLTGTPIQNNMQELWALLHFIMPTLFDSHDEFSEWFSKDIESHAQSNTKLNEDQLKRLHMILKPFMLRRIKKHVQKELGDKVEKDVFCDLTYRQRAYYTSLRNRVSIMDLIEKAAIGDDTDSTTLMNLVMQFRKVCNHPDLFERAETTSPFSVCYFAETASFVREGPFVDVGYSTRNLVEYDLPRLLCSPEGRLDVAGPGNNKAGFEGRYLSHLMNIWTPENIRESMSHNDAFSWLRFADTSVGEAYEVSHKGVFERAVRRRDYSTRLSLLDVAYDAEDGVNINSVHVHSLFNIVERNDRRALADITATGYMRELLNVASNVAERGGIRTIEPCAKPGASAPPITISCSGQAAIAEARATFFNTAVRHALFAAPTKAMEEEILSNKLDPAPYSLRPLLPQPGSMKGRYTNITVPSMRRFVTDSGKLAKLDELLRELKNGGHRVLLYFQMTRMIDLMEEYLTYRNYKYCRLDGSTKLEDRRDTVSDFQQRPEIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTKQVTVYRLITRGTIEERIRKRALQKEEVQRVVISGGAAGGVDFNARSRENRTKDIAMWLADDEQAEILEQKEKEALEKGEELGAKKGRKAAGKRKRDITLDDMYHEGEGHFEDNSTKPSGAATPVSGDVSGVPGVKGRRGRGGGGVGRSKKAKTMKERLRLVDGEVD

Protein

Chromatin-remodeling ATPase INO80: INO80

Gene

Ino80

Protein

Chromatin-remodeling ATPase INO80

Organism

Drosophila melanogaster

Length

1638 amino acids

Function

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

187.086 kDa

Sequence

MEAKPVPAPQPRPRAMAEPLHIQRLEAALNMRPFMNMAKRSLRKPLSSDEETDDEHVVKREHDVQDSDDSSTVGVVRMKQSSKRKSRLLASKEERQSVKAQLYNFNDLTSDREWLYDLLLSDTESDDPTITEDEYVQQLLREHVREQRQRKNYYKKAANAQYAYYGSGLLSNHDIFAERQLATAGVRKRRRRTKQEILMARLAEAQAGPKPPKQRRRGRKKRDNMGSPESGEVPPSELGKYTFGDTLPNNEDDDEDGGEVDYKRELASLALDYPEEEEIEEEVDVEGGTEGQVTKVRRKRKNPAALAARRRRIWQIMSKKESGRLQRIKSNNHKEMLANCKRVAGMCAKVVRQRAINSQRIMKETVWRAKRLTREMLAYWKRYERVERDQRRKQEREAEEQRKQDVELIEVKRQQRKLNFLITQTELYAHFMSKKLGQGSEEDQLRILSQLDEETNARLAAQDDYDAGEMKLLAQENAEAAMQRDLDKTRAFDVFAKKKEKEEEEQAQESVEDIKPEPRPEMKDLPQPKMFKGTLKGYQIKGMTWLANIYDQGISGILADEMGLGKTVQSIAFLCHIAEHYGVWGPFLVISPASTLHNWQQEMSRFVPDFKVVPYWGSPAERKILRQFWDQKHLHTRDASFHVVITSYQLVVSDYKYFNRIKWQYMVLDEAQAIKSAASQRWKLLLGFSCRNRLLLSGTPIQNSMAELWALLHFIMPTLFDSHDEFNEWFSKDIESHAENKTGIDEKQISRLHMILKPFMLRRIKKDVENELSDKIEIMVYCPLTIRQKLLYRALKQKIRIEDLLHLTSGSTTTSSSSSASNLMNLVMQFRKVCNHPELFERRDARSPFFMRCAEYTIPRLIHEEGLIHRMLPSRKHLLYNRFNIFKSEYIQRSLFEDVNVNSCFGFTRLCDLSVGDMVEVTLNGLIDFLLHYRRVLEKYPLLAYRRFWWKKQPDSRYQLLEPMLENKLALDYMPPNSVLKNFIFTAMTANESSVYAFGDYFTYNMQETIEHRVIRSKILKKKTSLIEEMEDVSKQKLEIESVEVQTKSNAKSDVKVTTLLLLPEFPHRPRKPRKYVCEPLSMPRILYDLGQKVQAVHRYLYCDSRSAAWSQIRHNQCENSQGRELVSSGLALCKPHGGWSSIVVPDKETLITDAGKLFVLDNLLTRLKANGHRVLIYSQMTKMIDLLEEYMWHRKHRYMRLDGSSKISARRDMVADFQTRADIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKGTIEERILQRAREKSEIQRMVISGGNFKPDTLKPKEVVSLLLDDEEIEMKYRQEAKLQSSSPIPAATQSERKRRHPQKDVNMGGTTIAATSATQNPDDDVPSCSSAAKRIKLETEEDFIDVGITSSASSVGTDSNHPTLSQETYVPGATCVQQTEIDSENEALVVDGDSPTMLGQNESMNFLDDLSGISPMRRRHHPRGTRRGRPRGSTRRGGGHGSIPRVLTPTQAATPAVPATASQAAAAGTGAAAGTSSPLPQQEVSGGGDNAGVPLHEEEYRTSPSGQSPGVSCKRGPGRPRSKTATPISRGTRGAPRARRPMGPLLVPLGRSPDDTPPSSSPATSRAPSPLSGSHGAVGPE

Protein

Chromatin-remodeling ATPase INO80: Ino80

Gene

ino80

Protein

Chromatin-remodeling ATPase INO80

Organism

Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)

Length

1612 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

181.601 kDa

Sequence

MTGAPPYHPQSPTQQSHYAGYSPSNKPRHYYPNSEHYQQQPPQTPPAFPQPNLARSPHYSHAPSPLPGALPPLNGGAPTPAHPSDPSPQYQAHSAAGTPQYPLPRPYSGSLLPASGTSPYGPSTPSHAHPSSRPDSHAHVSPKKEPESHFAVNHGAPAYSVMREPQASPPKEAKPARAADPMSFASILSGPTEEQAPPKIQSPTPGLGTIHSAVPAANATSLNPPPASFHPKVGDIEPVPPVSAPRLEKKPSADKRQRNTEKEDLKSAENPTNGVTEPPKILRPPRRIMSEKETEMVNKYMVEIDNAEKSDVEAPGFEQERERYILKGKKRALDVERAESIRRKRRRHDYLLKLGKSFEKQANAGMDRFRYANEASVISEVQAKEIQDEKERKKDMQRKRRRENTVRMEMQKKLEAELKANETQDSAEKAKFLREAERAQRKIKTTKRALEGVTEPEEIGEITPLAPNLEGGITSSFHIGRSSPSRRKTGRGGPVTRPKKSKEQKQAEKDAAEAAYAAMENDEPLPLAPREDPRKESLKKDAKGGRSKEATPVPVSTYESKGYNQIYEQIWRDIARKDIPKVYRTKVNSLSTRQENLRKTAQLASKQSRKWQERTNKSMKDTQARAKRTMREMMSFWKRNEREERDLRRLAEKQELESAKRAEAEREANRQKRKLNFLISQTELYSHFIGRKIPGAGGESGDAGVQGTEAMDLTPGAGAKVTNFEDLDFDAEDDTALRQAAMANAQSAVQKAQERARAFDDPNKSTMDTMDDSELNFQNPTSLGDIEISQPTMLTAKLKEYQLKGLNWLVNLYEQGINGILADEMGLGKTIQSISVMAYLAEVHNIWGPFLVIAPASTLHNWQQEITKFVPNIKVLPYWGNAKDRKILRKFWDRKHITYTKESEFHVLVTSYQLVVLDAQYFQKVKWQYMILDEAQAIKSSQSSRWKSLLGFHCRNRLLLTGTPIQNNMQELWALLHFIMPTLFDSHDEFSEWFSKDIESHAQSNTKLNEDQLRRLHMILKPFMLRRVKKHVQQELGDKVEKDVFCDLTYRQRALYTNLRNRVSIMDLIEKAAVGDETDSTTLMNLVMQFRKVCNHPDLFERAETKSPFSLAHFAETASFNIKQSIEDDGAFSFLRFVDTSVGEAFNYSHQGVFERALRRRGQTNRLSRLSVVYDEDESSTATLPHTLFNIVDRNDRQAVYDIAVEGHMRELMNVSRSVFEQEGLNVIEPCAGPAASAPPITLVSSGQEALIETQDALFNVPVQHALFGTPSKAMEEQIIEQQLDPTPYSLPPMLPEPISTKGRYTHIEVPSMRRFVTDSGKLAKLDELLRELKAGGHRVLLYFQMTRMIDLMEEYLTYRNYKYCRLDGSTKLEDRRDTVADFQQRPDIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLITRSTIEERIRKRALQKEEVQRVVISGGAAGGVDFNTRNRDSKTKDIAMWLADDEQAELIEQKEREALERGETFGASKGGKKNAQKRKRDVTLDDMYHEGEGNFDDASAKPSGAATPVSTAENIGTPSASTPVPKRGRGRGGKGTAKRAKTTKERLRLIDGDGGLGSG

Protein

Chromatin-remodeling ATPase INO80: ino80

Gene

ino80

Protein

Chromatin-remodeling ATPase INO80

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

Length

1604 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

183.049 kDa

Sequence

MDPSRETFDGSTRDSYKPPNGAEMMGQSELNTQNRIPYNTSANNRNWQIPLYWQQRGNEFQASPPPPLGYVTPEYGATGTPVNANNASRVDYATTAANVPEEYANDYSSELAYIHNVNDMPHVDGLSNHSPATQPDLFETPAQSDPILFSSYPHAAQARVDPSISKDLYNMVPRPDANTVSPHAARSASSLPVPKEASETPFRDASTDLFDEHAHAAPMHSSISISTLLSDSDRYEPHVSLTENISPVMAPSIDARLSQTILRGLPPAQKLSPNSSQSQITHNRRKHKLPLNATTNNSVVLTPDTSPLLDSDEVVSDDDSNEQQTMMMKFNYLQHLRNKRDEAVHAEKRRLLDIRGSIHDRLVCRYENRYNKLHASEYNHHHDWAVRQAIREEVAAVEAAKIRADEEKKKKEREEQVRLLQESADKDAEMNEASTATSENEDLKDDLSLADLSSKKTANSQATENNNTPSKAKVKAESKVRSKAKSDKSRAKLSSDTNKDSEKNDNNDASLQSAGVASDGESSPETPLTKASKSKKAKASKLANDTSKNANGETKSTPKKSKKKTSKAQQEANSTTAEGKEKLSGDSTETGNSTNKEASTEDTKANATASAPNKKKKTVETLQQQVIKEIARKEIPRVYKIIQQNQYNRSTNARKTSQLCGREARRWQFRTIKNNKDMQTKAKRAMRETMVFWKRNERVERDLRKKAEREALDRAKKEEELRESRRQARKLDFLITQTELYSHFVGRKMDREQDLPSATNTASVSEINFDSDEEEDIRRLAVESAQEAVQKAREHSQLFDANRQQSPNNSSSDMNEGEMNFQNPTLVNAFEVKQPKMLMCKLKEYQLKGLNWLANLYEQGINGILADEMGLGKTVQSISVMAYLAETHNIWGPFLVIAPASTLHNWQQEITRFVPKLKCIPYWGSTKDRKILRKFWCRKNMTYDENSPFHVVVTSYQLVVLDAQYFQSVKWQYMILDEAQAIKSSSSSRWKSLLAFKCRNRLLLTGTPIQNTMQELWALLHFIMPSLFDSHNEFSEWFSKDIESHAQSNTQLNEQQLKRLHMILKPFMLRRVKKNVQSELGEKIEKEVYCDLTQRQKILYQALRRQISIAELLEKAILGGDDTVASIMNLVMQFRKVCNHPDLFEREDVRSPLSLATWSKSIYINREGNFLDVPYNTRNFITFSIPRLLYEQGGILSVPGLNTSRGFETKYLYNLMNIWNPEYTNDSIKSNPEGSPFSWLRFVDESPQTLFQTFQNPVVHYLDEAEASSSLKEEQLCRQEFCYGKDYSNVRKMLLLPKSITKVDVLGSDFKEDSPFYHLTHVLEESDSQLDLTLLDSVLVQRASAPPIDIYCPGSRQFTVLQSRFQRDHLWSHYLYQPLKGEEDLIINNQAVSKLPIPRKPLLPSFGIAKGSYSNVRIPSMLRFIADSGKLSKLDKLLVELKANDHRVLIYFQMTRMIDLMEEYLTFRQYKYLRLDGSSKISQRRDMVTEWQTRPELFVFLLSTRAGGLGINLTAADTVIFYDSDWNPSIDSQAMDRAHRIGQQKQVTVYRFITRGTIEERIVIRAKEKEEVQKVVISGGETRPTKQMDLKGNSREMVSWLLEE

Protein

Chromatin-remodeling ATPase INO80: ino80

Gene

INO80

Protein

Chromatin-remodeling ATPase INO80

Organism

Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)

Length

1575 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

177.637 kDa

Sequence

MNILSMLSNDSAVQLQLQLQLQLQLQLNLQSAPSKASPPTLLPKQTTATTTNATGNTKTVARYSAGDINILNDENSHGVDESIDEPVTNGQATNKESVKQEPTQPTNNTETEKKPLTLSIQNGADKKSLPPQSQPPRINPLVADVTLSTSKFKNVLAHIQHDQLEIDLDYKFKFESNVSLIDQLDKNQRLSQDLRILKFDEVKSNNYLISTHQFTTNYIDRVVAEDISSRNNKISDTNKNKEIIHIDHSKPLHHNSTRGKEYKWGSTREIHKVESKPKRKRNTENSETNNSRSTVSSKASTPSKSLAFGSTHHVPIRPKGSKGTNLSSSSGPITDITNDSNNVRRSSRPKSKRKAYEDGEGEDNGNNIDSNSTDNNNRNKTQEGGRGPKRIRIKLKVKPEGENEGEEKDEGKGKGRGKGKGKGKGKGKEKDGDKEEEDENNANGENGKSKGSVSSSTTTTTTAAAAAAGGGGSTGSALGTTTSNSSTSKEQKAFMRQYDNTYVAIWKDMSRKDGPKVSRLMQQSTQAKLINLKKTCILAAREAKRWQVKNTKNQKDLSTKARRAMREMFNFWKRNERIERELKKKHEKELVEKAKREEEERESKRQSRKLNFLITQTELYSHFIGKKIKTDEIEGTDADPRIKAQEKAHLDKYAGVDAANNDILAIDFDNDDEDALHRAAAQNAQNALANAQNQAKQFDDTEPFKNPDTNGEEMNFQNPTLLGDLSIEQPKMLKCTLKEYQIKGLNWLANLYEQGINGILADEMGLGKTVQSISVLSYLAETHNIWGPFLVVTPASTLHNWQQEISKFVPNFKVLPYWGHAKDRKVLRKFWDRKSLRYDKDAPFHVLVTSYQLIVSDIAYFQKMKWQYMILDEAQAIKSSQSSRWKSLLSLSCRNRLLLTGTPIQNSMQELWALLHFIMPTLFDSHDEFSDWFSKDIESHAQSNTGLDEQQLRRLHMILKPFMLRRIKKNVQSELGDKVEIDLFCDLTNRQKKYYQSLRSQISIMDLIDATTTNSSSNNSSLDDSSTTSLVNLVMQFRKVCNHPDLFERADVRSPMALVKFAETGSFLREGNDLDVSYASENLINYNLPRLIYDDLISANENKNDFGSVYAKFSVYDPENLRDLGWISSAGTSPNEIQQLGKMNVLERAIKLQRYTTGSPLDRINYLYEGDYSSPNSKLLINPQNQHMISQQQIENSSVLLDLCNISQKVYEEMYLNTQDPAFTPLASAPPITIVCSSNNFQNKLQNELFNPTIRSALAPMSLNKELEFMNNNTPLELYPPSNMLPSSLSKVNDYSNIRMPSMDRFITESGKLAKLDELLVKLKQEDHRVLIYFQMTKMMDLMEEYLTFKQHKYIRLDGSSKLDDRRDLVHDWQTKPEIFVFLLSTRAGGLGINLTAADTVVFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLLTRNTIEERMRDRAKQKEQVQQVVMEGKATTIMSKKEDAASKKKDVAFLLLGGSGDGDGDGTGVNSGVDTSNDVSKSTTPKPEVGKKKNNGNKKNVFGNGKKRVREEDGEEEDALNSKRLQELYHEGEGEFSGTVTPAPGV

Protein

Chromatin-remodeling ATPase INO80: INO80

Gene

Ino80

Protein

Chromatin-remodeling ATPase INO80

Organism

Mus musculus

Length

1559 amino acids

Function

ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair. Binds DNA. As part of the INO80 complex, remodels chromatin by shifting nucleosomes. Regulates transcription upon recruitment by YY1 to YY1-activated genes, where it acts as an essential coactivator. Involved in UV-damage excision DNA repair. The contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Involved in DNA replication. Required for microtubule assembly during mitosis thereby regulating chromosome segregation cycle.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

176.52 kDa

Sequence

MASELGAGDDGSSTELAKPLYLQYLERALRLDHFLRQTSAIFNRNISSDDSEDGLDDNNPLLPESGDPLIQVKEEPPNSLLGETSGASSSGLLNPYSLNGVLQSESKSDKGNLYNFSKLKKSRKWLKSILLSDESSEADSQSEDNDDEEEELSLSREELHNMLRLHKYKKLHQNKYSKDKELQQYQYYSAGLLSTYDPFYEQQRHLLGPKKKKFKEDKKLKAKLKKVKKKRRRDEEFSSEESPRHHHHQTKVFAKFSHDAPPPGTKKKHLSIEQLNARRRKVWLSIVKKELPKANKQKSSARNLFLTNSRKLAHQCMKEVRRAALQAQKNCKETLPRARRLTKEMLLYWKKYEKVEKEHRKRAEKEALEQRKLDEEMREAKRQQRKLNFLITQTELYAHFMSRKRDMGHDGIQEEILRKLEDSSTQRQIDIGGGVVVNITQEDYDSNHFKAQALKNAENAYHIHQARTRSFDEDAKESRAAALRAADKSGSGFGESYSLANPSIRAGEDIPQPTIFNGKLKGYQLKGMNWLANLYEQGINGILADEMGLGKTVQSIALLAHLAERENIWGPFLIISPASTLNNWHQEFTRFVPKFKVLPYWGNPHDRKVIRRFWSQKTLYTQDAPFHVVITSYQLVVQDVKYFQRVKWQYMVLDEAQALKSSSSVRWKILLQFQCRNRLLLTGTPIQNTMAELWALLHFIMPTLFDSHEEFNEWFSKDIESHAENKSAIDENQLSRLHMILKPFMLRRIKKDVENELSDKIEILTYCQLTSRQKLLYQALKNKISIEDLLQSSMGSTQQAQNTTSSLMNLVMQFRKVCNHPELFERQETWSPFHISLKPYEISKFIYRHGQIRVFNHSRDRWLKVLLSPFAPDYIQQSLFHRKGINEGSCFSFLRFIDVSPAEMANLMLQGLLARWLALFLSLKASYRLHQLRSWAEPDGTSHQSYLRNKDFLLGVDFPLSFPNLCSCPLLKSLVFSSHCKAVSGYSDHVVHQRRSATSSLRCCLLTELPSFLCVASPRVTAVPLDSYCNDRSAEYERGVLKEGGSLAAKQCLLNGAPELATDWLSRRSQFFPEPAGGLLSIRPQNGWSFIRIPGKESLITDSGKLYALDVLLTRLKSQGHRVLIYSQMTRMIDLLEEYMVYRKHTYMRLDGSSKISERRDMVADFQTRNDIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKGTIEERILQRAKEKSEIQRMVISGGNFKPDTLKPKEVVSLLLDDEELEKKLRLRQEEKRQQEESNRVKERKRKREKYAEKKKKEDELDGKRRKEGVNLVIPFVPSADNSNLSADGDDSFISVDSAMPSPFSEISISSELHTGSIPPDESSSDMLVIVDDPASSAPQSRATNSPASITGSVSDTVNGISIQEVPAAGRGHSARSRGRPKGSGSTAKGAGKGRSRKSTAGSAAAMAGAKAGAAAASAAAYAAYGYNVSKGISASSPLQTSIVRPAGLADFGPSSASSPLSSPLNKGNNIPGTPKSLHMTSSLASDSLIRKQGKGTNPSGGR

Protein

Chromatin-remodeling ATPase INO80: Ino80

Gene

INO80

Protein

Chromatin-remodeling ATPase INO80

Organism

Homo sapiens

Length

1556 amino acids

Function

ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair (PubMed:16230350, PubMed:16298340, PubMed:17721549, PubMed:20855601, PubMed:20237820). Binds DNA (PubMed:16298340, PubMed:21303910). As part of the INO80 complex, remodels chromatin by shifting nucleosomes (PubMed:16230350, PubMed:21303910). Regulates transcription upon recruitment by YY1 to YY1-activated genes, where it acts as an essential coactivator (PubMed:17721549). Involved in UV-damage excision DNA repair (PubMed:20855601). The contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation (PubMed:20687897). Involved in DNA replication (PubMed:20237820). Required for microtubule assembly during mitosis thereby regulating chromosome segregation cycle (PubMed:20237820).

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

176.753 kDa

Sequence

MASELGARDDGGCTELAKPLYLQYLERALRLDHFLRQTSAIFNRNISSDDSEDGLDDSNPLLPQSGDPLIQVKEEPPNSLLGETSGAGSSGMLNTYSLNGVLQSESKCDKGNLYNFSKLKKSRKWLKSILLSDESSEADSQSEDDDEEELNLSREELHNMLRLHKYKKLHQNKYSKDKELQQYQYYSAGLLSTYDPFYEQQRHLLGPKKKKFKEEKKLKAKLKKVKKKRRRDEELSSEESPRRHHHQTKVFAKFSHDAPPPGTKKKHLSIEQLNARRRKVWLSIVKKELPKANKQKASARNLFLTNSRKLAHQCMKEVRRAALQAQKNCKETLPRARRLTKEMLLYWKKYEKVEKEHRKRAEKEALEQRKLDEEMREAKRQQRKLNFLITQTELYAHFMSRKRDMGHDGIQEEILRKLEDSSTQRQIDIGGGVVVNITQEDYDSNHFKAQALKNAENAYHIHQARTRSFDEDAKESRAAALRAANKSGTGFGESYSLANPSIRAGEDIPQPTIFNGKLKGYQLKGMNWLANLYEQGINGILADEMGLGKTVQSIALLAHLAERENIWGPFLIISPASTLNNWHQEFTRFVPKFKVLPYWGNPHDRKVIRRFWSQKTLYTQDAPFHVVITSYQLVVQDVKYFQRVKWQYMVLDEAQALKSSSSVRWKILLQFQCRNRLLLTGTPIQNTMAELWALLHFIMPTLFDSHEEFNEWFSKDIESHAENKSAIDENQLSRLHMILKPFMLRRIKKDVENELSDKIEILMYCQLTSRQKLLYQALKNKISIEDLLQSSMGSTQQAQNTTSSLMNLVMQFRKVCNHPELFERQETWSPFHISLKPYHISKFIYRHGQIRVFNHSRDRWLRVLSPFAPDYIQRSLFHRKGINEESCFSFLRFIDISPAEMANLMLQGLLARWLALFLSLKASYRLHQLRSWGAPEGESHQRYLRNKDFLLGVNFPLSFPNLCSCPLLKSLVFSSHCKAVSGYSDQVVHQRRSATSSLRRCLLTELPSFLCVASPRVTAVPLDSYCNDRSAEYERRVLKEGGSLAAKQCLLNGAPELAADWLNRRSQFFPEPAGGLWSIRPQNGWSFIRIPGKESLITDSGKLYALDVLLTRLKSQGHRVLIYSQMTRMIDLLEEYMVYRKHTYMRLDGSSKISERRDMVADFQNRNDIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKGTIEERILQRAKEKSEIQRMVISGGNFKPDTLKPKEVVSLLLDDEELEKKLRLRQEEKRQQEETNRVKERKRKREKYAEKKKKEDELDGKRRKEGVNLVIPFVPSADNSNLSADGDDSFISVDSAMPSPFSEISISSELHTGSIPLDESSSDMLVIVDDPASSAPQSRATNSPASITGSVSDTVNGISIQEMPAAGRGHSARSRGRPKGSGSTAKGAGKGRSRKSTAGSAAAMAGAKAGAAAASAAAYAAYGYNVSKGISASSPLQTSLVRPAGLADFGPSSASSPLSSPLSKGNNVPGNPKNLHMTSSLAPDSLVRKQGKGTNPSGGR

Protein

Chromatin-remodeling ATPase INO80: INO80

Gene

INO80

Protein

Chromatin-remodeling ATPase INO80

Organism

Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294)

Length

1556 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

180.155 kDa

Sequence

MSLAKLLNNDDDDNNINLPNINVNNTNTNDTSSSIVTNTHTTNTTTNLQKEKFLNKLNNDFNLLNKRDNLELNYQDWKFLNYQEFELLNEWNQQSKEWNNSIKNFEYLYSLMKKYKSEWENYLTLKSSDKYLKNVVNDCLINSNTNNLKSKSKLKTDTKTKAKSKSKSKLKLKSNSDAKVKSKSSNAKAKAKTKSVSTQQKRKRTTSIKNLLEKEDSALTSLDDMDEIDDVNEILNNDNNDEITQNSKDLSTTTATEKKLNTKTSPSKKRKDEVRVAMKKPMTSTPNVKTENKSKQKSNKKNIDADDNTYDDNNLINGKDTEELDDIEKAKDLEDNTDIEIEGTNENEDEDEDEDEDEDEDEEDEEEGEEEEEEEEDEEGVINMIENEDDEDYFAPGKKSGRQNASKVAGEPAAPVPKTPTTIHSDRERIVRELIKMCNKNKNKKSRKRRFTNSIVTDYNPEENKLIVKVTLKQYHVRKLKKLINDAKKLREEEEMKLKKSLMKEAENAEELEGPSSKKKKLNSGTAQNENGGEQNSEFIQNTHDLPTYGMQMTLKEAKAIKRHYDNTFFTILKDLARKDSAKMARLVQQIQSIRATNFKKNSSVCAREARKWQQRNFKQVKDFQTRARRGIREMLNYWKKNEREERDLKKKAEKVAMEQARKEEEDRENVRQAKKLNFLLTQTELYSHFIGSKIKTNELEGNMKDDEFDENEDNLMNNIDLDSTSSVKTDFKTIDFDNEDDDELRRKAAQNASNVLQKSREKTKKFDNDTSNGEELNFQNPTSLGEVVIEQPSILACTLKEYQLKGLNWLANLYDQGINGILADEMGLGKTVQSISVLAHLAEKYNIWGPFLVVTPASTLHNWVNEISKFVPQFKILPYWGNSNDRKILRRFWDRKNLRYNKDSPFHVMITSYQMVVSDTSYLQKMKWQYMILDEAQAIKSSQSSRWRNLLSFHCRNRLLLTGTPIQNNMQELWALLHFIMPSLFDSHDEFNDWFSKDIESHAEANTKLNQQQLRRLHMILKPFMLRRVKKNVQSELGDKIEIDVMCDLTQRQAKLYQILKSQMSTNYDVIENAAGDDDTGSDQNMINAVMQFRKVCNHPDLFERADVDSPFSFSIFGKSSSLSRDNEPLVDILYSTRNPITYHLPRLIYNDLILPNYENDLGLKNKLLNYTFSIFNNESTCKEISRVTGLTYGEIKRVVHRDLLMNAIHLKEPYSRQTFLEKISVIEDNDKTFSDMNFKSNLKLIERSAKLDALSRVTSTGVLNSLLNIKEQVFDNEYYNAISRSYHPNVSSSPVSIQVLGNRHFSIQQEEELFKPVISKALSEIPASTQYNMAVEKKIPLHDFPVSGLYPSPLNKSFSSYISMPSMDRFITESAKLKKLDELLVELKKGDHRVLIYFQMTKMMDLMEEYLTYRQYSHIRLDGSSKLEDRRDLVHDWQTRPDIFIFLLSTRAGGLGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLLIRGTIEERMRDRAKQKEHVQQVVMEGKTLQKDVKTIESGGDVKAAAAASTALTTN

Protein

Chromatin-remodeling ATPase INO80: INO80

Gene

INO80

Protein

Chromatin-remodeling ATPase INO80

Organism

Arabidopsis thaliana

Length

1507 amino acids

Function

ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair (By similarity). Binds DNA (By similarity). As part of the INO80 complex, remodels chromatin by shifting nucleosomes (By similarity). Positive regulator of homologous recombination, but not an essential component of homologous recombination (PubMed:15525519). Not involved in the illegitimate repair pathway (PubMed:15525519).

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

172.172 kDa

Sequence

MDPSRRPPKDSPYANLFDLEPLMKFRIPKPEDEVDYYGSSSQDESRSTQGGVVANYSNGSKSRMNASSKKRKRWTEAEDAEDDDDLYNQHVTEEHYRSMLGEHVQKFKNRSKETQGNPPHLMGFPVLKSNVGSYRGRKPGNDYHGRFYDMDNSPNFAADVTPHRRGSYHDRDITPKIAYEPSYLDIGDGVIYKIPPSYDKLVASLNLPSFSDIHVEEFYLKGTLDLRSLAELMASDKRSGVRSRNGMGEPRPQYESLQARMKALSPSNSTPNFSLKVSEAAMNSAIPEGSAGSTARTILSEGGVLQVHYVKILEKGDTYEIVKRSLPKKLKAKNDPAVIEKTERDKIRKAWINIVRRDIAKHHRIFTTFHRKLSIDAKRFADGCQREVRMKVGRSYKIPRTAPIRTRKISRDMLLFWKRYDKQMAEERKKQEKEAAEAFKREQEQRESKRQQQRLNFLIKQTELYSHFMQNKTDSNPSEALPIGDENPIDEVLPETSAAEPSEVEDPEEAELKEKVLRAAQDAVSKQKQITDAFDTEYMKLRQTSEMEGPLNDISVSGSSNIDLHNPSTMPVTSTVQTPELFKGTLKEYQMKGLQWLVNCYEQGLNGILADEMGLGKTIQAMAFLAHLAEEKNIWGPFLVVAPASVLNNWADEISRFCPDLKTLPYWGGLQERTILRKNINPKRMYRRDAGFHILITSYQLLVTDEKYFRRVKWQYMVLDEAQAIKSSSSIRWKTLLSFNCRNRLLLTGTPIQNNMAELWALLHFIMPMLFDNHDQFNEWFSKGIENHAEHGGTLNEHQLNRLHAILKPFMLRRVKKDVVSELTTKTEVTVHCKLSSRQQAFYQAIKNKISLAELFDSNRGQFTDKKVLNLMNIVIQLRKVCNHPELFERNEGSSYLYFGVTSNSLLPHPFGELEDVHYSGGQNPIIYKIPKLLHQEVLQNSETFCSSVGRGISRESFLKHFNIYSPEYILKSIFPSDSGVDQVVSGSGAFGFSRLMDLSPSEVGYLALCSVAERLLFSILRWERQFLDELVNSLMESKDGDLSDNNIERVKTKAVTRMLLMPSKVETNFQKRRLSTGPTRPSFEALVISHQDRFLSSIKLLHSAYTYIPKARAPPVSIHCSDRNSAYRVTEELHQPWLKRLLIGFARTSEANGPRKPNSFPHPLIQEIDSELPVVQPALQLTHRIFGSCPPMQSFDPAKLLTDSGKLQTLDILLKRLRAGNHRVLLFAQMTKMLNILEDYMNYRKYKYLRLDGSSTIMDRRDMVRDFQHRSDIFVFLLSTRAGGLGINLTAADTVIFYESDWNPTLDLQAMDRAHRLGQTKDVTVYRLICKETVEEKILHRASQKNTVQQLVMTGGHVQGDDFLGAADVVSLLMDDAEAAQLEQKFRELPLQVKDRQKKKTKRIRIDAEGDATLEELEDVDRQDNGQEPLEEPEKPKSSNKKRRAASNPKARAPQKAKEEANGEDTPQRTKRVKRQTKSINESLEPVFSASVTESNKGFDPSSSAN

Protein

Chromatin-remodeling ATPase INO80: INO80

Gene

INO80

Protein

Chromatin-remodeling ATPase INO80

Organism

Saccharomyces cerevisiae (strain YJM789)

Length

1495 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. Its ability to induce transcription of some phosphate-responsive genes is modulated by inositol polyphosphates. The INO80 complex is involved in DNA repair by associating with 'Ser-129' phosphorylated H2A histones as a response to DNA damage.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

172.093 kDa

Sequence

MSLAVLLNKEDKDISDFSKTTAGKSAKKNSRERVADVAPTRVLDKKQAYLSQLNSEFNRIKKRDSIEQLYQDWKFINLQEFELISEWNQQSKDWQFDNTNDSQDLHFKKLYRDMSMINKEWAEYQSFKNANLSDIINEKDADEDEEDDEDELEDGEEDMEEDEASTGRHTNGKSMRGNGIQKSRKKDAAAAAAVGKAIKDDQTHADTVVTVNGDENEDGNNDEDNDNDNENNNDNDNDNDNDNDNDNENENDNDNDNDDEEENGEEDEEEEEIEDLDEEDFAAFEEQDDNDDEDFNPDVEKRRKRSSSSSSSTKLSMNSLSLITSKKINKNITINSDRPKIVRELIKMCNKNKHQKIKKRRFTNCIVTDYNPIDSKLNIKITLKQYHVKRLKKLINDAKREREREEALKNNVGLDGNDLDNDEDGSESHKRRKLNNNTANGADDANKRKFNTRHGLPTYGMKMNAKEARAIQRHYDNTYTTIWKDMARKDSTKMSRLVQQIQSIRSTNFRKTSSLCAREAKKWQSKNFKQIKDFQTRARRGIREMSNFWKKNEREERDLKKKIEKEAMEQAKKEEEEKESKRQAKKLNFLLTQTELYSHFIGRKIKTNELEGNNVSNNDSESQKNIDISALAPNKNDFHAIDFDNENDEQLRLRAAENASNALAETRAKAKQFDDHANAHGEEEEEDELNFQNPTSLGEITIEQPKILACTLKEYQLKGLNWLANLYDQGINGILADEMGLGKTVQSISVLAHLAENHNIWGPFLVVTPASTLHNWVNEISKFLPQFKILPYWGNANDRKVLRKFWDRKNLRYSKNAPFHVMVTSYQMVVTDANYLQKMKWQYMILDEAQAIKSSQSSRWKNLLSFHCRNRLLLTGTPIQNSMQELWALLHFIMPSLFDSHDEFNEWFSKDIESHAEANTKLNQQQLRRLHMILKPFMLRRVKKNVQSELGDKIEIDVLCDLTQRQAKLYQVLKSQISTNYDAIENAATNDSTSNSASNSGSDQNLINAVMQFRKVCNHPDLFERADVDSPFSFTTFGKTTSMLTASVANNNSSVISNSNMNLSSMSSNNISNGKFTDLIYSSRNPIKYSLPRLIYEDLILPNYNNDVDIANKLKNVKFNIFNPSINYELCLFLSKLTGEPSLNEFFRVSNTPLLKRVIERTNGPKNTDSLSFKTITQELLEVTRNAPSEGVMASLLNVKKHAYEREYLNCIQRGYHPNVSAPPVTIEVLGSSHVTNSINNELFDPLISQALSDIPAITQYNMHVKKGIPVEDFPKTGLFPEPLNKNFSSNISTPSMDRFITESAKLRKLDELLVKLKSEGHRVLIYFQMTKMMDLMEEYLTYRQYNHIRLDGSSKLEDRRDLVHDWQTNPEIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLLVRGTIEERMRDRAKQKEQVQQVVMEGKTQEKNIKTIEVGENDSEVTREGSKSISQDGIKEAASALA

Protein

Chromatin-remodeling ATPase INO80: INO80

Gene

INO80

Protein

Chromatin-remodeling ATPase INO80

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

1489 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (PubMed:10952318, PubMed:12887900). Its ability to induce transcription of some phosphate-responsive genes is modulated by inositol polyphosphates (PubMed:10952318, PubMed:10361278). The INO80 complex is involved in DNA repair by associating with 'Ser-129' phosphorylated H2A histones as a response to DNA damage (PubMed:15607974, PubMed:15607975).

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

171.455 kDa

Sequence

MSLAVLLNKEDKDISDFSKTTAGKSAKKNSRERVADVAPTRVLDKKQAYLSQLNSEFNRIKRRDSIEQLYQDWKFINLQEFELISEWNQQSKDWQFDNTNDSQDLHFKKLYRDMSMINKEWAEYQSFKNANLSDIINEKDADEDEEDDEDELEDGEEDMEEDEASTGRHTNGKSMRGNGIQKSRKKDAAAAAAIGKAIKDDQTHADTVVTVNGDENEDGNNGEDEDNDNDNENNNDNDNDNENENDNDSDNDDEEENGEEDEEEEEIEDLDEEDFAAFEEQDDNDDEDFNPDVEKRRKRSSSSSSSTKLSMNSLSLITSKKINKNITINSDRPKIVRELIKMCNKNKHQKIKKRRFTNCIVTDYNPIDSKLNIKITLKQYHVKRLKKLINDAKREREREEALKNNVGLDGNDLDNDEDGSESHKRRKLNNNTANGADDANKRKFNTRHGLPTYGMKMNAKEARAIQRHYDNTYTTIWKDMARKDSTKMSRLVQQIQSIRSTNFRKTSSLCAREAKKWQSKNFKQIKDFQTRARRGIREMSNFWKKNEREERDLKKKIEKEAMEQAKKEEEEKESKRQAKKLNFLLTQTELYSHFIGRKIKTNELEGNNVSSNDSESQKNIDISALAPNKNDFHAIDFDNENDEQLRLRAAENASNALAETRAKAKQFDDHANAHEEEEEEDELNFQNPTSLGEITIEQPKILACTLKEYQLKGLNWLANLYDQGINGILADEMGLGKTVQSISVLAHLAENHNIWGPFLVVTPASTLHNWVNEISKFLPQFKILPYWGNANDRKVLRKFWDRKNLRYNKNAPFHVMVTSYQMVVTDANYLQKMKWQYMILDEAQAIKSSQSSRWKNLLSFHCRNRLLLTGTPIQNSMQELWALLHFIMPSLFDSHDEFNEWFSKDIESHAEANTKLNQQQLRRLHMILKPFMLRRVKKNVQSELGDKIEIDVLCDLTQRQAKLYQVLKSQISTNYDAIENAATNDSTSNSASNSGSDQNLINAVMQFRKVCNHPDLFERADVDSPFSFTTFGKTTSMLTASVANNNSSVISNSNMNLSSMSSNNISNGKFTDLIYSSRNPIKYSLPRLIYEDLILPNYNNDVDIANKLKNVKFNIFNPSTNYELCLFLSKLTGEPSLNEFFRVSTTPLLKRVIERTNGPKNTDSLSFKTITQELLEVTRNAPSEGVMASLLNVEKHAYEREYLNCIQRGYHPNVSAPPVTIEVLGSSHVTNSINNELFDPLISQALSDIPAITQYNMHVKKGIPVEDFPKTGLFPEPLNKNFSSNISMPSMDRFITESAKLRKLDELLVKLKSEGHRVLIYFQMTKMMDLMEEYLTYRQYNHIRLDGSSKLEDRRDLVHDWQTNPEIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLLVRGTIEERMRDRAKQKEQVQQVVMEGKTQEKNIKTIEVGENDSEVTREGSKSISQDGIKEAASALA

Protein

Chromatin-remodeling ATPase INO80: INO80

Gene

INO80

Protein

Chromatin-remodeling ATPase INO80

Organism

Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)

Length

1489 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

170.981 kDa

Sequence

MSLEKLLNREENDSSKRTDFMGRWYLKMSKICERDDREMDYQNWKFLSYQEFELINEWNQQGKELTKDNCERLLVNMDKTHKEWVEYQKFKEQKDAIIAELKESIQIIKQEPSIPSGADANSVVSSDTEQIQDSETTANSKKSPAINGIKTSGKSPTKSPATNGRRRGAGGNRRVKRPSNLSKTVRSRNATDGDENGNENIENGGTTPKRRSRPKKILVSNVSKDVDAEEEDDIHTEKDASGSAADLDKDIVDESINDSENAPRKRPVSSTSLLSRNKSNKPTKSSPLTPDSAREKENVNGVTEGNEDMDHDSVLDADDSAIGSDDNPNDEQEEADDENVDEEAEDENDEAEVEDDIDDLGAPEDDGDDDFAPSYSAISKVKVNKKVNIDSPMPAIQKELRKMAIKSSVAKAMKRKFTNCKVISYSPESQLEIKITLKQLHIRKYKRHLAEEERKRKAEEALIKAEEEAKKRKLAPPPPPPPQQVRRVEHDLPTYGMKITLKEARAIQRHYDQTYITIWKDMARRDSGRISRQLQQIQSIRGQNFRKTSSLCAKEARRWQMRNFRQVKDFQTRARRGIREMSSFWKKNEREEREMKKKAEKEAIEQAKKEEEQRENLRAAKKLNFLLTQTELYSHFIGSKIKTNELEGTMTDDSLTSMSNNKNKVVDLTKTAASKTNVESIDFATEDDEKLRLMAAQNASNALKETQDKARKFDEEDEEDGELNFQNPTSLGEITIDQPKMLACTLKEYQLKGLNWLANLYDQGINGILADEMGLGKTVQSISVLAHLADRYNIWGPFIVVTPASTLHNWVNEISRFVPQFKILPYWGNANDRKTLRKFWDRKHLRYGRDAPFHVMVTSYQMVVSDASYLQKMKWQYMILDEAQAIKSSQSSRWKTLLSFHCRNRLLLTGTPIQNNMQELWALLHFIMPSLFDSHDEFSDWFSKDIESHAESNTELNQEQLRRLHMVLKPFMLRRIKKNVQSELGDKIEIDVLCDLTFRQAKLYQVLKSQVSGGYDAIENAAGNDDVTSDQKLVNLVMEFRKVCNHPDLFERADVMSPFSFVSFGESASLSREGDFVEVNYSAKNLINYNLPRLIYDELVVPNYNNDVDVRAKLLYHTMNIFHPANSFQLCFILSKLTDTSPNKFATLLEQNVINRAIDLQNDGYFNTAKYSIAYDEGEKIFSSNLLINDKLKYLHLLKNSTSGSVLKNLLEIPSSVYENEYFNSISPAYHPAASAPPINIDVLASNNFVQKKQYEMFNPSISSALSSIPSSVQHKLIVEKGIPIEELPVTEMAPKAFNNSFTSYIEMPSMDRFITESAKLKKLDELLVKLKEEDHRVLIYFQMTKMMDLMEEYLTYRQYTHIRLDGSSKLDDRRDLVHDWQTKPDIFIFLLSTRAGGLGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLLIRGTIEERMRDRAKQKEHVQQVVMEGKAKENKQKIIEVEKEHSESA

Protein

Chromatin-remodeling ATPase INO80: INO80

Gene

INO80

Protein

Chromatin-remodeling ATPase INO80

Organism

Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)

Length

1484 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

170.54 kDa

Sequence

MSLSALLNNDDPVEDTKLYLESLNREMDRLIKRDQLELMYQDWKFANYQEFELISEWNTQCKELVGDGNDLQNNDLMTEEVHLDDLYDNIQRIRNEWKDYESYKETRSQLLSKSIQAKPIKHRRRRRTKLEMEAAANLAALSQMGTTDVKTPEIINDHGNRSKASRSDTTNKTDNTMAGINSPTSDVDSGHKDELDQTKLIKKQEASSSTNSAASVTASVANGIVEDQKDEAERTIEANRIGSNMQNSDQDTMDDLKKTNDPSSDIDSDANTSVNDGSDENLSNKLDSDDLHSEPADNEEEPVSSDAEKDQAENINQTDESEEEIIVKEYDDNNDEDFAPEIKKPKPNGKIVTINSDRPKIVRELIKLRNKGKAPKSSKRRYTAVNITEYSPTEKKISVKITLKQMHVKKLKKILQDARKAEEKRLQEEAKQIADQESPRKRRKIDRSENTKQEDEDDKEDDDLDGLPTYGMKMSLKDAKAIQRHYDNTYTMIWKDMARKDCMKISRLVQQIQSTRALNYKKTSSLCAREARKWQTRNFKQVKDFQTRARKGIREMANFWKKNEREERDLKKKAEREALELAKKEEEEKESKRQAKKLNFLLTQTELYSHFIGRKIKTSALEGNEVAEEDEDNYDLTTTAPNKNDFHAIDFDNENDEQLKLKAAQNASNALAETRAKAKAFDDAHRQQQSTESDDEEEMNFQNPTSLGEITIEQPKMLACTLKEYQLKGLNWLANLYDQGINGILADEMGLGKTVQSISVLAHLAEHHNIWGPFLVVTPASTLHNWVNEISKFVPQFKILPYWGSANDRKVLRKFWDRKNLRYSEKSPFHVMITSYQMVVADASYLQKMKWQYMILDEAQAIKSSQSSRWKNLLSFHCRNRLLLTGTPIQNNMQELWALLHFIMPSLFDSHDEFNEWFSRDIESHAEGNSSLNQQQLRRLHMILKPFMLRRIKKNVQSELGDKIEIDVMCDLTQRQTKLYQVLKSQMSSNYDAIENAAAEGSDIAGGGNSDQSIINAVMQFRKVCNHPDLFERADINSPFSFTSFGKTSSLISSSIATSGGLTETISELMYSSTNPINCAIPKLIYEDLILPNYNNSIDIMEKLLLSDFSIYDPVNNKEMCQYLGLLTGLAYGSFRKIHKSNYFERIINLKKESKQSSQNLITVVSNANDLIADSIVHADTNLPNLTGIRNDIYHNDYLNSIQPGYCPKVVAPPINFNVNGSLNFTNKMSSYLFNPVITTALSSIPPPTQYNMFVKKCIPIEEFPISEMYPNPLNKHFSSNISMPSMDRFITESAKLKKLDELLVELKKNDHRVLIYFQMTKMMDLMEEYLTYRQYNHIRLDGSSKLEDRRDLVHDWQTNPEIFIFLLSTRAGGLGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTKQVTVYRLLVRGTIEERMRDRAKQKEQVQQVVMEGKTKDTNIQTTHTRPEHEQLTPKSLSSEPEATNNLITVKN

Protein

Chromatin-remodeling ATPase INO80: INO80

Gene

ino80

Protein

Chromatin-remodeling ATPase INO80

Organism

Aspergillus oryzae (strain ATCC 42149 / RIB 40)

Length

1444 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

164.774 kDa

Sequence

MSFASILSGPAEERSPPKRQSPPPETTPAPVTSTPREATQLSPPPPPHVPPSHQKVKEQEQVLPRLEKKPSSEKRRRNAEQDNKAGEPSNGILSNGIPEPTKTTTQSWSFLSPRKVLSERESETINKLMVEIDNAEKSDVEAPGFEEEYEQYKLQCKRRALHTLKEEGIKRKRRRNTFLVNLGKSLEKQASAGMDRFRIANEASVISEVQAKEIQDEKERKKDMQRKRRRENTVRLEMQKKLEAERKANKAQDSAEKAKFLREAERAQRKIKTTKRALEGVTAPEEIGEVTPLAPNLEGGTTSSFHIGRSSPSRRKSGRGGPVTRPKKSKEQKQAEKDAAEAAYAAMENDEPLPLAPKEDPRKESLKKEAKGSRSKESSPAPLSAFETKGYNQIYEQIWRDIARKDIPKVYRIKALSLSTRQENLRKTAQLASKQSRKWQERTNKSMKDTQARAKRTMREMMSFWKRNEREERDLRRLAERQEIESAKKAEAEREANRQRRKLNFLISQTELYSHFIGRKIKGAEGDSGDTAVEGSDETVQPGKDEEHAMEDAGAKVTNFEDLDFDAEDETALRQAAMANAQNAVKEAQDRARAFNDGQDHMAALDEGELNFQNPTSLGDIEISQPTMLTAKLKEYQLKGLNWLVNLYEQGINGILADEMGLGKTIQSISVMAYLAEVHNIWGPFLVIAPASTLHNWQQEITKFVPDIKVLPYWGSAKDRKILRKFWDRKHITYTKESEFHVLVTSYQLVVLDAQYFQKVKWQYMILDEAQAIKSSQSSRWKNLLGFSCRNRLLLTGTPIQNNMQELWALLHFIMPTLFDSHDEFSEWFSKDIESHAQSNTKLNEDQLKRLHMILKPFMLRRVKKHVQQELGDKVEKDVFCDLTYRQRAYYTNLRNRVSIMDLIEKAAVGDEADSTTLMNLVMQFRKVCNHPDLFERAETKSPFSVAHFAETASFVREGQNVDVGYSTRNLIEYPLPRLLCGSDGRVDVAGPGNLHAGFRGKYLAHLMNIFAPENIKHSAEHDGTFSFLRFVDTSINEAYEQSHQGIFERAVRRRGKPNRLSRLNVVYDDDKATMASALPHTMFNIVQRNDQHAINDVTTEGYMRELTTVAQSAFERKGLGIIEPCVSPAASAPPITVSSSSRAPLSEMNDSLFNVSVRHALFSTPSKQLEQQILEKKLDPIPYSLPPMLPQPISIKGRYTHIEVPSMRRFVTDSGKLAKLDELLRELKAGGHRVLLYFQMTRMIDLMEEYLTYRNYKYCRLDGSTKLEDRRDTVADFQQRPEIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLITRGTIEERIRKRALQKEEVQRVVISGGAAGGVDFNTRNRESRTKDIAMWLADDEQAELIEQKEKEALDRGEVFGASKGGKKAAQKRKRDITLDDMYHEVSFAIH

Protein

Chromatin-remodeling ATPase INO80: ino80

Gene

INO80

Protein

Chromatin-remodeling ATPase INO80

Organism

Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)

Length

1414 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

161.209 kDa

Sequence

MSLEALLNKEEKGSGAAREAFMRRMNERFNSVCHKDAREQQYQDWKYLSYQEFELVNEWSAASRELTVNQCGQLLSNVKSAQAEWLAYEEFVAGRARLVAEVEAKREREQEEQEERQPARAKTKERARARGTAKRAVGRKATKAPAAPAEQEGGVPAARAAAKAPVRAEGAAEPPLKRELSGAKLEDEGEGEDDDEEEDEDDEDDEDEDEDEDEEEEEEEELEELEDIQLLDDDNDKDFSPEGGRSKSSIKLNTKLDINSDIALIQRELLKMAQKHKSAKAKKRKFTSCVVQRYDSDHTRLEVKVTLKQLHIKRLKRLLNEAKRKRAAEEALAANEQQGNLAKRRKTAQKQKPAANGAPAASSSEDVTVTEAATPVPAKVNGEAPSNESPVAAIPDINPTTGLPTYGMKMTAKEARAIQRHYDTTYITVWKDMARKDSAKLSRLVQQIQSIRSANFKKTSSLVAREARKWQSRNFRQVKDFQTRARRGVREMSSFWKKNEREERELKKRAEREAIEQAKKEEEERESKRQARKLNFLLTQTELYSHFIGSKIKTNELEGNMADSNLATAPDVSAIDLSKPPTRKNEVHTIDFDNEDDEELHRKAAQNASNALKETREKAKAFDGMSGDDEELNFQNPTSLGEITIEQPKILACTLKEYQLKGLNWLANLYDQGINGILADEMGLGKTVQSISVLAHLAERYNIWGPFIVVTPASTLHNWVNEIQKFVPDFKILPYWGNGNDRKILRRFWDRKHLRYSKDAPFHVMITSYQMIVSDAAYLQKMKWQYMILDEAQAIKSSQSSRWKNLLSFHCRNRLLLTGTPIQNSMQELWALLHFIMPSLFDSHDEFNDWFSKDIESHAQSNTQLNQQQLRRLHMILKPFMLRRIKKNVQSELGDKIEIDVMCDLTHRQAKLYQVLKSQVSASYDAIENAASNSSGDDSGNMSLSDSKIMNTVMEFRKVCNHPDLFERADVSSPFSFTSFGQTGSIMREGDVIDVQYSSKNPVSFHLPRLIYDDLILPNYNHDSDMRTKILNHMMSIFAPANSPDLCATLSKVAGVEPNSILRLSQEHIVKRAIDLSAHSPNVTRSGIFSVVYEDDKSSLSSLDKTLLINDKSDYLHTIARTTQNGVLASLLNIQGNFYENEYMNVLRPAYRPAAAAPPISIHVMGSSNFSIKRDNALFEPYITRSLGIIPPELQTRLTEKENNIFTALPISELYPAPLNKSFSSYISMPSMDRFITESAKLKKLDELLVRLKAGEHRVLIYFQMTRMMDLIEEYLTYRQYKHIRLDGSSKLEDRRDLVHDWQTKSDIFIFLLSTRAGGLGINLTSADTVIFYDSDWNPTIDSQAMDRAHRLGQTKQVTVYRLLIKGTIEERMRDRAKQKEHVQQVVMEGKTKENNVQTITANGKTLENLPLPL

Protein

Chromatin-remodeling ATPase INO80: INO80

Gene

INO80

Protein

Chromatin-remodeling ATPase INO80

Organism

Candida albicans (strain SC5314 / ATCC MYA-2876)

Length

1387 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

158.823 kDa

Sequence

MNISSMLSSDNNVSLKESMTTATDQQQQQQAESVDHASINGNGQTSVSAVNNVQENHLSEFHSSNQQHSSIPPVGTTVEHATTTTTTATNHQPVNSSPLKHSVDENSNPTTISSLKKDTNSIIASILPESYQFDNSYTPTIDQKYKSVFESNINVINQLDQYQQMGHHLKLMKFDEVKLNNYLINTGQFASNYIDRVVAEDISSRNNKISETNKNKELIAIDYSKPLHHNSTRGKEFKWGSTRKIHKVEHKSRRRKPAATTSTTDDSNKAVAAAANGTKDHSATAGTTASANGSDTPDRRHQRQSSKPSTPILIKPKTEPGKGSPEIQPRRSSRPKVKRKAFEDELETADKQSSTQQVKKSQESTGRDHKRVKIENKQEEQQQHQQQQQADEEDEAEAEAEAEQKPKSGALSEAAAAGMTAKEFKAFMRQYDNTYIAIWKDLSRKDGPKGSRSMQQATQGRLINLRKTALLAAREAKRWQLKNTKNQKDLTTKARRAMREMFNFWKRNERLERDLKKKHEKELLDKAKKEEEEREAKRQSRKLNFLITQTELYSHFIGKKIKTDELEGTNADDNLKSNTKEHLDKYADVDGSATHDINAVDFDNDDEEALRRMAAQNAQNALIEVQNKAKQFDNSEESFKNPDTNGEEMNFQNPTLLGDITIPQPNMLKCTLKEYQLKGLNWLANLYEQGINGILADEMGLGKTVQSISVLAYLAETYNMWGPFLVVTPASTLHNWQQEITKFVPEFKVLPYWGNAKDRKILRKFWDRKSLRYDKDSPFHVLVTSYQLIVADIAYFQKMKWQYMILDEAQAIKSSSSSRWKSLLNLTCRNRLLLTGTPIQNSMQELWALLHFIMPSIFDSHDEFSDWFAKDIESHAQSNTSLDEQQLRRLHMILKPFMLRRIKKNVQSELGDKVEIDVYCDLTTRQKKLYQQLRSQISMSDTDLLELESNSTSSDSSLANLVMQFRKVCNHPDLFERADVNSPFSFGKFAETGSFLRETNELDVNYSTENIVQYDLPRLIYDELLTPNYNKSIRDSIYSKFSIYNPENMNATGWLQGINVSPNELKHYSQMDILSRAIEMQNKPTETEKLERINYLYEGDYIPKNKKLLITDHSTSTNSSFISNSLVFSDLVSIKEKVGEDMYLNKLEPAVTPIASAPPITVNCSSMNFTNKMNNTLFDSNIRSSLIPLSLSTELKLMKDQIPLEQYPKSNMLPMPIFDYSNIRMPSMDRFIAESGKLAKLDELLIDLKRGGHRILIYFQMTRMMQIFEEYLAYKSYKYIRLDGSTTIESRREMVQAWQTNPEIFIFMLSTRAGGLGLNLTSADTVIFYDSDWNPTIDSQAMDRAHRIGQTKQVKVFRLVTRNTIEQKILERAKEKEEIQKLVVGNM

Protein

Chromatin-remodeling ATPase INO80: INO80

Gene

INO80

Protein

Chromatin-remodeling ATPase INO80

Organism

Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)

Length

1364 amino acids

Function

ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.

Similarity

Belongs to the SNF2/RAD54 helicase family.

Mass

155.935 kDa

Sequence

MNISSMLSNDSNTASQDVGGNFDDSQRNNDKGGSQDANSKKMGTGEAEDHANGNASVEGNGIANHGSATNGNTKGTDDSSNVNIVESIIPKPIRPTRSSIESDEEDVGKNYNSIISNDSEHISQRYLENFEDKVNAINKIDQVLIKGNNMRVLNQEEENLNILIRNSGEIAENYIDRVVTEDISSKANILNGKDSVGKEFKWGSTRDMKKRELELEVDNASKADTAAKKGGNKSKQGATKSTPAKKAKAKPKRKPSATDDTSEESQLGKKRKTRAGSVSGASQNDEKSANGKVKLKLTLKDQAEEDSASADAASKVTTKEQKIITKQYDNTFVSIWKDLSRKDGPKVSRLMQQSTQAKMINLKKTSILAAREAKRWQLKNNRNQKDLTTKARRAMREMFNFWKRNERIERELRKKHEKEILDKAKKEEEERESKRQSRKLNFLITQTELYSHFIGKKIKTDEFEGTDSDPNANFKSANHHYDKYSNIDGEGKDFNSIDFDNEDEESLNKAAAVNAQIALEAAKTKAQAFDNDPLKNPDTNGEEMNFQNPTLLGDINISQPDLLKCTLKEYQVKGLNWLANLYEQGINGILADEMGLGKTVQSISVLAYLAETHNIWGPFLVVTPASTLHNWQQEISRFVPEFKVIPYWGNAKDRKVLRKFWDRKNFRYGKDAPFHVLVTSYQLVVADAAYFQKMKWQYMILDEAQAIKSSQSSRWKSLLSFSCRNRLLLTGTPIQNSMQELWALLHFIMPSLFDSHDEFSDWFSKDIESHAQSNTELNEQQLRRLHVILKPFMLRRIKKNVQSELGDKLEIDVFCDLTHRQKKYYQMLTSQISIMDLLDSANNSSDDSAQSLMNLVMQFRKVCNHPDLFERADVKSSFAFGRFAETSSFLRETNELEMSYSTENLIKYNMPRIVYEEILQPTFDNDVGSRKKINNMFNIYHPSNIANDELENFSWLRFVDQSPQEMNNLSKQNIIERAINNREYSDINYERINRLKYTYDEDNESFLPNSKLLLINELQNNHALISNSTYLKELYSIKKKVYEDMVINNMKPAAEPLVKAPPVAVVCDNISFVHDLQDSLFDPKIRSSLMPLPFNRELELLKSSIPITEYPKSNMLPNAINKFIDYSNIRMPSMNRFITESGKLSKLDELLVDLRQNDHRVLIYFQMTKMMDLMEEYLTYRQHKYIRLDGSSKLDDRRDLVHDWQTKPEIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLLTRGTIEERMRDRAKQKEQVQQVVMEGKSAIANKEESGNKKKDVAFLLLGNDDSSAAALNDDSEEKQNLQDSKKSQAKNLEDMYHEGEGEFSGNVTPSL

Protein

Chromatin-remodeling ATPase INO80: INO80