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IL1A

Gene
IL1A
Protein
Interleukin-1 alpha
Organism
Homo sapiens
Length
271 amino acids
Function
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Similarity
Belongs to the IL-1 family.
Mass
30.607 kDa
Sequence
MAKVPDMFEDLKNCYSENEEDSSSIDHLSLNQKSFYHVSYGPLHEGCMDQSVSLSISETSKTSKLTFKESMVVVATNGKVLKKRRLSLSQSITDDDLEAIANDSEEEIIKPRSAPFSFLSNVKYNFMRIIKYEFILNDALNQSIIRANDQYLTAAALHNLDEAVKFDMGAYKSSKDDAKITVILRISKTQLYVTAQDEDQPVLLKEMPEIPKTITGSETNLLFFWETHGTKNYFTSVAHPNLFIATKQDYWVCLAGGPPSITDFQILENQA

Gene
IL1A
Protein
Interleukin-1 alpha
Organism
Macaca fascicularis
Length
271 amino acids
Function
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).
Similarity
Belongs to the IL-1 family.
Mass
30.686 kDa
Sequence
MAKVPDMFEDLKNCYSENEEVSSSIDHLSLNQKSFYDVSYGPLHEGCMDQSVSLSISEISKTSKLTFKQSMVVVSTNGKVLKKRRLSLSQSITDNNLEAIANDSEEEIIKPRSAPFSFLSNMTYHFIRIIKHEFILNDTLNQTIIRANDQYLTAAAIHNLDEAVKFDMGAYTSSKDDTKVPVILRISKTQLYVSAQDEDQPVLLKEMPEIPKTITGSETNFLFFWETHGTKNYFISVAHPNLFIATKHDNWVCLAKGLPSITDFQILENQA

Gene
IL1A
Protein
Interleukin-1 alpha
Organism
Macaca mulatta
Length
271 amino acids
Function
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Similarity
Belongs to the IL-1 family.
Mass
30.693 kDa
Sequence
MAKVPDMFEDLKNCYSENEEDSSSIDHLSLNQKSFYDVSYGPLHEGCMDQSVSLSISEISKTSKLTFKQSMVVVSTNGKVLKKRRLSLSQSITDNNLEAIANDSEEEIIKPRSAPFSFLSNMTYHFIRIIKHEFILNDTLNQTIIRANDQHLTAAAIHNLDEAVKFDMGAYTSSKDDTKVPVILRISKTQLYVSAQDEDQPVLLKEMPEINKTITGSETNFLFFWETHGTKNYFISVAHPNLFIATKHDNWVCLAKGLPSITDFQILENQA

Gene
IL1A
Protein
Interleukin-1 alpha
Organism
Cercocebus atys
Length
271 amino acids
Function
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Similarity
Belongs to the IL-1 family.
Mass
30.451 kDa
Sequence
MAKVPDMFEDLKNCYSENEEDSSSIDHLFLNQKSFYDVSYGPLHESCMDQSVSLSISEISKTSKLSFKQSMVVVSTNGKVLKKRRLSLSQSIADDNLEAIANDSEEEIIKPRSAPFSFLSNMTYHIIRIIKHESILNDTLNQTIIRANDQYLTAAAIHNLDEAVKFDMGAYTSSKDDTKVPVILRISKTQLYVSAQDEDQPVLLKEMPEIPKTTTGGETNSLSSWETRGTKNYFISVAHPNLFIATKHDNWVCLAKGLPSITDFQILENQA

Gene
Il1a
Protein
Interleukin-1 alpha
Organism
Mus musculus
Length
270 amino acids
Function
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Similarity
Belongs to the IL-1 family.
Mass
31.023 kDa
Sequence
MAKVPDLFEDLKNCYSENEDYSSAIDHLSLNQKSFYDASYGSLHETCTDQFVSLRTSETSKMSNFTFKESRVTVSATSSNGKILKKRRLSFSETFTEDDLQSITHDLEETIQPRSAPYTYQSDLRYKLMKLVRQKFVMNDSLNQTIYQDVDKHYLSTTWLNDLQQEVKFDMYAYSSGGDDSKYPVTLKISDSQLFVSAQGEDQPVLLKELPETPKLITGSETDLIFFWKSINSKNYFTSAAYPELFIATKEQSRVHLARGLPSMTDFQIS

Gene
IL1A
Protein
Interleukin-1 alpha
Organism
Sus scrofa
Length
270 amino acids
Function
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Similarity
Belongs to the IL-1 family.
Mass
30.789 kDa
Sequence
MAKVPDLFEDLKNCYSENEEYSSDIDHLSLNQKSFYDASYEPLPGDGMDKFMPLSTSKTSKTSRLNFKDSVVMAAANGKILKKRRLSLNQFITDDDLEAIANDTEEEIIKPRSATYSFQSNMKYNFMRVINHQCILNDARNQSIIRDPSGQYLMAAVLNNLDEAVKFDMAAYTSNDDSQLPVTLRISETRLFVSAQNEDEPVLLKELPETPKTIKDETSLLFFWEKHGNMDYFKSAAHPKLFIATRQEKLVHMAPGLPSVTDFQILENQS

Gene
Il1a
Protein
Interleukin-1 alpha
Organism
Rattus norvegicus
Length
270 amino acids
Function
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Similarity
Belongs to the IL-1 family.
Mass
30.856 kDa
Sequence
MAKVPDLFEDLKNCYSENEEYSSAIDHLSLNQKSFYDASYGSLHENCTDKFVSLRTSETSKMSTFTFKESRVVVSATSNKGKILKKRRLSFNQPFTEDDLEAIAHDLEETIQPRSAPHSFQNNLRYKLIRIVKQEFIMNDSLNQNIYVDMDRIHLKAASLNDLQLEVKFDMYAYSSGGDDSKYPVTLKVSNTQLFVSAQGEDKPVLLKEIPETPKLITGSETDLIFFWEKINSKNYFTSAAFPELLIATKEQSQVHLARGLPSMIDFQIS

Gene
IL1A
Protein
Interleukin-1 alpha
Organism
Felis catus
Length
270 amino acids
Function
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).
Similarity
Belongs to the IL-1 family.
Mass
30.798 kDa
Sequence
MAKVPDLFEDLKNCYSENEEYSSEIDHLTLNQKSFYDASYDPLHEDCTDKFMSPSTSETSKTPQLTLKKSVVMVAANGKILKKRRLSLNQFLTADDLEAIANEVEEEIMKPRSVAPNFYSSEKYNYQKIIKSQFILNDNLSQSVIRKAGGKYLAAAALQNLDDAVKFDMGAYTSKEDSKLPVTLRISKTRLFVSAQNEDEPVLLKEMPETPKTIRDETNLLFFWERHGSKNYFKSVAHPKLFIATQEEQLVHMARGLPSVTDFQILETQS

Gene
IL1A
Protein
Interleukin-1 alpha
Organism
Equus caballus
Length
270 amino acids
Function
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).
Similarity
Belongs to the IL-1 family.
Mass
30.807 kDa
Sequence
MAKVPDLFEDLKNCYSENEDYSSEIDHLSLTQKSFYDASYDPLPEDCMDTFMSLSTSETSKTSKLNFKESVVLVAANGKTLKKRRLSLNQFITNDDLEAIANDPEEGIIRPRSVHYNFQSNTKYNFMRIVNHQCTLNDALNQSVIRDTSGQYLATAALNNLDDAVKFDMGAYTSEEDSQLPVTLRISKTRLFVSAQNEDEPVLLKEMPDTPKTIKDETNLLFFWERHGSKNYFKSVAHPKLFIATKQGKLVHMARGQPSITDFQILDNQF

Gene
IL1A
Protein
Interleukin-1 alpha
Organism
Lama glama
Length
268 amino acids
Function
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).
Similarity
Belongs to the IL-1 family.
Mass
30.653 kDa
Sequence
MAKVPDLFEDLKNCYSENEEYGSEIDHLSLNQKSFYDASHEPLHEDCMDKLMSLSTSETSKTSKLTFKESVVMVASNGKILKKRRLSLNQFITDDDLEAIANDTEEEIIKPRSVPYNLQSNVKYNYMRIVNHQCILNDALNRSIIRDPSGQYLMAAVLNNLDNAVKFDMGAYTSEEDSQLPVTLRISKTQLFVSAQNEDEPVLLKEMPETPKIIKDETNLLFFWEKHGSMDYFKSVAHPKLFIATKQEKLVHMASGPPSITDFQILEK

Gene
IL1A
Protein
Interleukin-1 alpha
Organism
Ovis aries
Length
268 amino acids
Function
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Similarity
Belongs to the IL-1 family.
Mass
30.925 kDa
Sequence
MAKVPDLFEDLKNCYSENEDYSSEIDHLSLNQKSFYDASYEPLREDHMNKFMSLDTSETSKTSRLSFKENVVMVTANGKILKKRRLSLNQFITDDDLEAIANDTEEEIIKPRSAHYSFQSNVKYNFMRVIHQECILNDALNQSIIRDMSGPYMTAATLNNLEEAVKFDMVAYVSEEDSQLPVTLRISKTQLFVSAQNEDEPVLHKEMPETPKIIKDETNLLFFWEKHGSMDYFKSVAHPKLFIATKQEKLVHMASGPPSITDFLILEK

Gene
IL1A
Protein
Interleukin-1 alpha
Organism
Bos taurus
Length
268 amino acids
Function
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Similarity
Belongs to the IL-1 family.
Mass
30.833 kDa
Sequence
MAKVPDLFEDLKNCYSENEDYSSEIDHLSLNQKSFYDASYEPLREDQMNKFMSLDTSETSKTSKLSFKENVVMVAASGKILKKRRLSLNQFITDDDLEAIANNTEEEIIKPRSAHYSFQSNVKYNFMRVIHQECILNDALNQSIIRDMSGPYLTATTLNNLEEAVKFDMVAYVSEEDSQLPVTLRISKTQLFVSAQNEDEPVLLKEMPETPKIIKDETNLLFFWEKHGSMDYFKSVAHPKLFIATKQEKLVHMASGPPSITDFQILEK

Gene
IL1A
Protein
Interleukin-1 alpha
Organism
Bubalus carabanensis
Length
268 amino acids
Function
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).
Similarity
Belongs to the IL-1 family.
Mass
30.748 kDa
Sequence
MAKVPDLFEDLKNCYSENEDYSSEIDHLSLNQKSFYDASYEPLREDQMDKFMSLDTSETSKTSRLSFKENVVMVAASGKILKKRRLSLNQFITDDDLEAIANNTEEEIIKPRSAHYSFQSNVKYNLLRVIHQECILNDALNQSLIRDLSGPYLTAATLNNLEEAVKFDMVAYVSEEDSQLPVTLRISKTQLFVSAQNEDEPVLLKEMPETPKIIKDETNLLFFWEKHGSMDYFKSVAHPKLFIATKQEKLVHMASGPPSVTDFQILEK

Gene
IL1A
Protein
Interleukin-1 alpha
Organism
Capra hircus
Length
268 amino acids
Function
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).
Similarity
Belongs to the IL-1 family.
Mass
30.856 kDa
Sequence
MAKVPDLFEDLKNCYSENEDYSSEIDHLSLNQKSFYDASYGPLREDHMNKFMSLDTSETSKTSRLSFKENVVMVTANGKILKKRRLSLNQFITDDDLEAIANDTEEEIIKPRSAHYSFQSNVKYNFMRVIHQECILNDALNQSIIRDMSGPYLMAATLNNLEEAVKFDMVAYVSEEDSQLPVTLRISKTQLFVSAQNEDEPVLLKEMPETPKIIKDETNLLFFWEKHGSMDYFKSVAHPKLFIATKQEKLVHMASGPPSITDFQILEK

Gene
IL1A
Protein
Interleukin-1 alpha
Organism
Oryctolagus cuniculus
Length
267 amino acids
Function
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Similarity
Belongs to the IL-1 family.
Mass
30.375 kDa
Sequence
MAKVPDLFEDLKNCFSENEEYSSAIDHLSLNQKSFYDASYEPLHEDCMNKVVSLSTSETSVSPNLTFQENVVAVTASGKILKKRRLSLNQPITDVDLETNVSDPEEGIIKPRSVPYTFQRNMRYKYLRIIKQEFTLNDALNQSLVRDTSDQYLRAAPLQNLGDAVKFDMGVYMTSEDSILPVTLRISQTPLFVSAQNEDEPVLLKEMPETPRIITDSESDILFFWETQGNKNYFKSAANPQLFIATKPEHLVHMARGLPSMTDFQIS

Gene
IL1A
Protein
Interleukin-1 alpha
Organism
Canis lupus familiaris
Length
265 amino acids
Function
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).
Similarity
Belongs to the IL-1 family.
Mass
30.522 kDa
Sequence
MAKVPDLFEDLKNCYSENEEYSSEIDHLSLNQKSFYDMSCDPLHEDCMSLSTSEISKTSQLTFKENVVVVAANGKILKKRRLSLSQFITDDDLEGIANDTEEVIMKPRSVAYNFHNNEKYNYIRIIKSQFILNDNLNQSIVRQTGGNYLMTAALQNLDDAVKFDMGAYTSEDSKLPVTLRISKTRLFVSAQNEDEPVLLKEMPETPKTIRDETNLLFFWERHGSKHYFKSVAQPKLFIATQERKLVHMARGQPSITDFRLLETQP

Gene
IL1A
Protein
Interleukin-1 alpha
Organism
Cavia porcellus
Length
204 amino acids
Function
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).
Similarity
Belongs to the IL-1 family.
Mass
23.333 kDa
Fragment
single
Sequence
FEDLKNCYSENEEYASAIDHLSLNQKSFYDTNYDPLHENRVDEPVSPNPYENSEESNFTLEDSSDSSAVVLTSAHGEVLKKRRLSLNQTMSNEDLEAIANDSEEEIIEPWSVPYSFQSNLKFKYQRSIKKGAVITDAMHQSLIRESNGQHLKAMHVVDRKHEVKFDIDGYVSTATRIRPVTLKISKTQLYVCAQEEGQPVLLKE