About Products Protein Database Contact

IGSF5

Gene
IGSF5
Protein
Immunoglobulin superfamily member 5
Organism
Homo sapiens
Length
407 amino acids
Function
Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells (By similarity).
Similarity
Belongs to the immunoglobulin superfamily.
Mass
44.593 kDa
Sequence
MGQKERSTADTLPDLEEWKSAAGLRWWQTAVVDGSGSGNEVIEGPQNARVLKGSQARFNCTVSQGWKLIMWALSDMVVLSVRPMEPIITNDRFTSQRYDQGGNFTSEMIIHNVEPSDSGNIRCSLQNSRLHGSAYLTVQVMGELFIPSVNLVVAENEPCEVTCLPSHWTRLPDISWELGLLVSHSSYYFVPEPSDLQSAVSILALTPQSNGTLTCVATWKSLKARKSATVNLTVIRCPQDTGGGINIPGVLSSLPSLGFSLPTWGKVGLGLAGTMLLTPTCTLTIRCCCCRRRCCGCNCCCRCCFCCRRKRGFRIQFQKKSEKEKTNKETETESGNENSGYNSDEQKTTDTASLPPKSCESSDPEQRNSSCGPPHQRADQRPPRPASHPQASFNLASPEKVSNTTVV

Gene
Igsf5
Protein
Immunoglobulin superfamily member 5
Organism
Mus musculus
Length
370 amino acids
Function
Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells.
Similarity
Belongs to the immunoglobulin superfamily.
Mass
40.292 kDa
Sequence
MEGSWRDVLAVLVILAQLTASGSSYQIIEGPQNVTVLKDSEAHFNCTVTHGWKLLMWTLNQMVVLSLTTQGPIITNNRFTYASYNSTDSFISELIIHDVQPSDSGSVQCSLQNSHGFGSAFLSVQVMGTLNIPSNNLIVTEGEPCNVTCYAVGWTSLPDISWELEVPVSHSSYNSFLESGNFMRVLSVLDLTPLGNGTLTCVAELKDLQASKSLTVNLTVVQPPPDSIGEEGPALPTWAIILLAVAFSLLLILIIVLIIIFCCCCASRREKEESTYQNEIRKSANMRTNKADPETKLKGGKENYGYSSDEAKAAQTASLPPKSAEVSLPEKRSSSLPYQELNKHQPGPATHPRVSFDIASPQKVRNVTLV

Gene
Igsf5
Protein
Immunoglobulin superfamily member 5
Organism
Rattus norvegicus
Length
369 amino acids
Function
Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells (By similarity).
Similarity
Belongs to the immunoglobulin superfamily.
Mass
40.281 kDa
Sequence
MEGSWRDVLAVLVILAQLTVSGSSYQIIEGPRNVTALKGSEARFNCTVTHGWKLIMWALNGIVELSLTSQKPIITSNRFTSASYNSTDSFISEMIIHNVQLNDSGPVQCSLQNSNVFGFAFLSVQVMGTLNIPSSNLIVTEGEPCNVTCYAVGWTPLPNISWELEVPVSHSSYYSFLEPGNSLRVLSVLDLTPLGNGTLTCVAEMKDLQASESLTVNLTVVQPPPDSIGGEGQALPTWAIILLAVAFSLLLILIIALIIIFCCCCVSRREKEESTYQNEIRKSANVRTGKADPETWLKSGKENYGYKSDEARAAQIASLPPKSGEVSLPEQRSSLPQQELDKHRPSPVTHPRVSFDIASPQKIRNVTIV