Protein
Insulin-like growth factor-binding protein 5
Function
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes anterior neural development by stimulating insulin growth factor (IGF) signaling via IGF receptors.
Sequence
MEMLLPMCLLLVSLCLGQCQALGSFVHCEPCDDKAMSMCPPTPVGCELVKEPGCGCCMTCALAEGHRCGVYTEHCAKGLRCLPEQGEEKPLHALLHGRGVCLNLKNHRDQSKIDRESREEDPTTSETEDIYQSKHRGKMRLSDQKAIALNTFRQKKHSQSRIVSVEKVQSPSTPEHSIEIDMGPCRRQVETLMQEMKLSHRVYPRAFYLPNCDRKGFYKRKQCKPSRGRKRGLCWCVDKYGLKLPGIDYVNGDLQCHSFDSSNTE