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IFT74

Gene
IFT74
Protein
Intraflagellar transport protein 74
Organism
Chlamydomonas reinhardtii
Length
641 amino acids
Function
Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic region. Required for ciliogenesis.
Similarity
Belongs to the IFT74 family.
Mass
71.54 kDa
Sequence
MDRPSSRGALALGAGGLGKAPTGGAVQQPDRPMTGQRGAAPAGPMRAPAGASIIGAGPPGTAMRGGPGPAGGPPGTAYKRMGTASQRPGTGQQAAAAAAAARAGQQLQVENRPITNHGVSGMKTAAAGVGRQVLDKNYFMNELRQKRMEIAQVTSNMKSDLEALERKQAQYNSMDKRASDLSKEVKILQEALADYNTVLDKVGSQAPVYVIQQEFAALKDRNEQQRKRVDEVLTERLNLESKAKQAESKMSEIQASMDQRLNSMPPSQRNEYTTLVAEQQQLQADSKRFEEVLDELDKALQASEGELARNPFKQRSLQLQEQIRALTEKKYELTEEERQSKRSPEELRADLMAKIKRDNTEVEQMTQQIRELQDQIKKMEERVKSLGGATSGAAAAEEKANREKFEELLAKERDLNNFMDGFPSRKAAKMQEKQQKEDGIVGVLEKMVKMQGIIGSNLPSQKKYKEMQDELEYKKMQLENTQTTQERLKEELTMRRTELEKIDTLEDKIKLELTQLAERQEAMEKEMGEFGSVEDIQRKANAARERMEGLRSVLLKRKDLLRSIVAERGLKFQAKRAQLQDHNLQVQLEKMEAKLKNLSAGVFEMDEFIKAKESETNYRQLASNIAALVDDLNVHVKKAVV
Protein
Intraflagellar transport protein 74: IFT74

Gene
IFT74
Protein
Intraflagellar transport protein 74 homolog
Organism
Homo sapiens
Length
600 amino acids
Function
Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic region. Required for ciliogenesis.
Similarity
Belongs to the IFT74 family.
Mass
69.239 kDa
Sequence
MASNHKSSAARPVSRGGVGLTGRPPSGIRPLSGNIRVATAMPPGTARPGSRGCPIGTGGVLSSQIKVAHRPVTQQGLTGMKTGTKGPQRQILDKSYYLGLLRSKISELTTEVNKLQKGIEMYNQENSVYLSYEKRAETLAVEIKELQGQLADYNMLVDKLNTNTEMEEVMNDYNMLKAQNDRETQSLDVIFTERQAKEKQIRSVEEEIEQEKQATDDIIKNMSFENQVKYLEMKTTNEKLLQELDTLQQQLDSQNMKKESLEAEIAHSQVKQEAVLLHEKLYELESHRDQMIAEDKSIGSPMEEREKLLKQIKDDNQEIASMERQLTDTKEKINQFIEEIRQLDMDLEEHQGEMNQKYKELKKREEHMDTFIETFEETKNQELKRKAQIEANIVALLEHCSRNINRIEQISSITNQELKMMQDDLNFKSTEVQKSQSTAQNLTSDIQRLQLDLQKMELLESKMTEEQHSLKSKIKQMTTDLEIYNDLPALKSSGEEKIKKLHQERMILSTHRNAFKKIMEKQNIEYEALKTQLQENETHSQLTNLERKWQHLEQNNFAMKEFIATKSQESDYQPIKKNVTKQIAEYNKTIVDALHSTSGN
Protein
Intraflagellar transport protein 74 homolog: IFT74

Gene
Ift74
Protein
Intraflagellar transport protein 74 homolog
Organism
Mus musculus
Length
600 amino acids
Function
Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic region. Required for ciliogenesis (By similarity).
Similarity
Belongs to the IFT74 family.
Mass
69.301 kDa
Sequence
MASNHKSSAPRPISRGGIGLTGRPPSGIRPPSGNVRVATAMPPTTARPGSRGGPLGTGGVLSSQIKVADRPVTQQGLSGMKTGMKGPQRQILDKSYYLGLLRSKISELTTEINKLQKEIEMYNQENSVYLSYEKRAETLAVEIKDFQGQLADYNMLVDKLNTNTEMEEVMSDYNMLKAQNDRETQSMDVIFTERQAKEKQIRSVEEEVEQEKQAADGIIKNMSPEKQVKYIEMKTTNEKLLQELDTLQQQLDSLNMKKESLETEIAHSQVKQEAVLLYEKLYELESHRDQMIAEDKSMGSPMEERERLLKQVKEDNQEIASMERQLTDIKEKINQFSEEIRQLDMDLEEHQGEMNQKYKELKKREENMDAFIETFEETKNQELERKAQIEASIITLLEHCSRNINRMKQISSITNQELKMMQDDLSFKSTEMQKSQTTARNLTSDSQRLQLDLQKMELLESKMTEEQQSLKNKIKQMTADLETYSDLAALKSSAEEKKKKLHQERTVLSTHRNAFKKIMEKLTSDYDTLKRQLQDNETHAQLTNLERKWQHLEQNNFVMKEFIATKSQESDYQPVIKNVMKQIAEYNKTIMDALHNASRS
Protein
Intraflagellar transport protein 74 homolog: Ift74