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IE2

Gene
IE2
Protein
Putative transcription activator BRLF1 homolog
Organism
Bovine herpesvirus 4 (strain DN-599)
Length
552 amino acids
Function
Transcription activation.
Similarity
Belongs to the herpesviridae TAF50 family.
Mass
60.963 kDa
Sequence
MKGIIYPRKSSADAYVYLSPGVREHLFSLLVKYTSSQRDSPAGSSTKVAPDTPQTNFIVEIQWVCHKILLEMEEQFGSLGGLVADINICLIWTLFRNYKHKHRMNNSDTGKSCAEYAQSVVKHLTERMVYCTDKFFINSACSGVTVPQNLALVIASISQVCRNKCQGAWRRMGNGRRTLIDLGLQLVNTYNLLNACGAIDDKCKAFIKLTFPYLNLETVYSPVHAASTGLHQKMAISLYKGQEKRKVPNATIYSNLVTQEKFALPEILLGEITDEGLLANKGPDLEKLLSEPQTILKLVTKLSPVSQFQVFMARWGDKLPSHLKDVCVSDSSQLPQQYENFKVVWPQHQTWPNDETSALPIASASLLSLQAENLPTSVQNSVAQETTGLPPQVPAGEMPPRGNCPVEDHGLLNSDAPDDLSGKGDYDLFTSDDLLPMSSGNVAIPVCEDPLAPPCKKQRMEPPDPLSTPGDNQWGDGAASAWIQSYMENEDAYLELILQGLYHLDEPPKLEDSIQVQDVSNSTNDPLEGPSRSQASCFEDTENIANPLDLFV

Gene
IE2
Protein
E3 ubiquitin-protein ligase IE2
Organism
Bombyx mori nuclear polyhedrosis virus
Length
422 amino acids
Function
RING-finger E3 ubiquitin ligase that plays an important regulatory role during the initial stages of infection. Migrates to specific nuclear foci early in infection supposely to prepare the sites for viral replication by targeting and ubiquitinating host proteins.
Similarity
Belongs to the alphabaculovirus IE2 protein family.
Mass
48.784 kDa
Sequence
MSRQINAVTPSSSSRRHRLSLSRRRINFTTSPEALPSSSSRSQPSSSSRSQPYSSSRSQPYSSSRRRRRQERSQEQRVSEDNVQIIGNANEPLTRTYHSQGVTYHVHGQVNISNDDPLLSQEDDTIESVDRASQQYQNSIASETAAQRALQRGLDLESQLMSEISPRSPAYSPPYPSNDVLSQSPDLFDSPQSPQQHELELEDEDEEEEEEEGEEVEVSCNICFTTLKDTKNVDSSFVTSIDCNHAVCFKCYVRIIMDNSTYKCFCSASSSDFRVYNKHGYVEFMPLTLIRNRDSIKQHWRELLENNTVNNRIIDLNDVERLERERSELRAKNSQVEHKMTMLNCDYAMLKHEHKITELKLKWANRDLEEFTKKTQELQSTVNDLQEQLRKQVAESQAKFSQFERRNSELVAELYTIEMSKP

Gene
IE2
Protein
E3 ubiquitin-protein ligase IE2
Organism
Autographa californica nuclear polyhedrosis virus
Length
408 amino acids
Function
RING-finger E3 ubiquitin ligase that plays an important regulatory role during the initial stages of infection. Migrates to specific nuclear foci early in infection supposely to prepare the sites for viral transcription and replication by targeting and ubiquitinating host proteins. Acts as a transcriptional activator and activates a number of viral promoters including itself, IE1 and the promoter of 39K gene.
Similarity
Belongs to the alphabaculovirus IE2 protein family.
Mass
47.007 kDa
Sequence
MSRQINAATPSSSRRHRLSLSRRRINFTTSPEAQPSSSSRSQPSSSSRSHRRQERRQEQRVSEENVQIIGNVNEPLTRTYHRQGVTYYVHGQVNISNDDPLLSQEDDVILINSENVDRERFPDITAQQYQDNIASETAAQRALQRGLDLEAQLMNEIAPRSPTYSPSYSPNYVIPQSPDLFASPQSPQPQQQQQQQSEPEEEVEVSCNICFTTFKDTKNVNSSFVTSIHCNHAVCFKCYVKIIMDNSVYKCFCSATSSDCRVYNKHGYVEFMPINVTRNQDSIKQHWRELLENNTVNNHTTDLNYVEQLQKELSELRAKTSQVEHKMTMLNSDYIMLKHKHAVAELDLQKANYDLQESTKKSEELQSTVNNLQEQLRKQVAESQAKFSEFERSNSDLVSKLQTVMSRR

Gene
IE2
Protein
E3 ubiquitin-protein ligase IE2
Organism
Rachiplusia ou multiple nucleopolyhedrovirus (strain R1)
Length
407 amino acids
Function
RING-finger E3 ubiquitin ligase that plays an important regulatory role during the initial stages of infection. Migrates to specific nuclear foci early in infection supposely to prepare the sites for viral replication by targeting and ubiquitinating host proteins.
Similarity
Belongs to the alphabaculovirus IE2 protein family.
Mass
46.665 kDa
Sequence
MSRQINAATPSSSRHHRLSLSRRRINFTTPSEAQPSSSSRSQTSSSSRSHRRQERRQEQRVSEENVQIIGNVNEPLTRSYHRQGVTYNVHGEVNISNADPLLSQEDDVILINSENVDRERFPDISSQQYQNNIASETAAQRALQRALDLEAQLMNEIAPRSPVYSPSYAPNSPNYVIPQSPDLFASPQSSEQQQQSEPEEDVEVSCNICFTTFKDTKNVNSSFVTTTHCNHAVCFKCYVKIIMANSVYKCFCSATSSNCRVYNKHGYVEFMPIDVTRNQDSIKQHWRELLENNTVNNQTTDLNYVEQLQKELAELRAKTCQVEHKMTMLNSDYIMLKHKHAVAELDLQKANYDLQESTKKSEELQSTVNNLQEQLNKQVVESQAKFLEFERNNSDLVSKLQTVMSRR

Gene
IE2
Protein
E3 ubiquitin-protein ligase IE2
Organism
Orgyia pseudotsugata multicapsid polyhedrosis virus
Length
405 amino acids
Function
RING-finger E3 ubiquitin ligase that plays an important regulatory role during the initial stages of infection. Migrates to specific nuclear foci early in infection supposely to prepare the sites for viral replication by targeting and ubiquitinating host proteins.
Similarity
Belongs to the alphabaculovirus IE2 protein family.
Mass
45.669 kDa
Sequence
MSRSNNANAPTPSNRRRNLSLVRGRRLTYSPPDAASAQRASPPRSAPRAAPRRVHAVGDPGAPLRASYALPNGVYNLHGDAHFNPPEEDDDILFVDTAAEQARQRAVNLHEAVNRHERLRRELGERMTRSPTLLNYSPSYSPTSPRSRSPDLIMPEDLQPAREQPLAPFNDSDDDERLLEQVMLESAEAPQLPQAPPAPQVDVSVLCHICSCTFTDIQNYNSNFVTSTECNHAVCFKCYVSIVFGKESYKCSICNRTTISCRAYNRDGYVELSTMSTVRDSQAIKRHWAQLSDSNMPHSNEMTTIQELQAELAELRAATARAHHDVNMARSDSQLLRQQLDVKEAELAHESNARLKLQKQNETLSANNLSLQHQLNTQVIESRVKMEQFKRQHDEFMEKFKLSLS

Gene
IE2
Protein
Immediate-early protein 2
Organism
Murid herpesvirus 1 (strain Smith)
Length
391 amino acids
Function
Involved in the reactivation of latent MCMV in spleen cells.
Similarity
Belongs to the herpesviridae US22 family.
Mass
43.801 kDa
Sequence
MERVRGASSSDSVATLHGDHNYHCMATFKLDCTSARTRGVVSILEHRDPATVDDIFMQRVCHDINDVLRPVECLTSFPEYRRTLRVAVEAATELHGVSALSGQLTKFLEDHDGAMLPLAWPPNRYLRLTSGRKLGYLDVAEKLRKEYPMCNGPLEVLGVILGPGQSLYSDQHPVLLMGLTGTIFLHARGRPVWSPDYDPERDADRLFLAAESLQSFGREGLCRCDNVYTEDGGAPYATPEDPVLKNIVFTPHLGGKALHQQICKIKGHTWYLNGCPGMLKDRVFVATPDIPPFVRHVNLELFGHRFLPIGRVTRSPEDPECEMFIMVDAGGAIYGHMLDSGKVRRLADNFDQFMRMGTRRVISISRWLREVVSTPSTRRPRLGPRTTGSFS

Gene
IE2
Protein
E3 ubiquitin-protein ligase IE2
Organism
Hyphantria cunea nuclear polyhedrosis virus
Length
375 amino acids
Function
RING-finger E3 ubiquitin ligase that plays an important regulatory role during the initial stages of infection. Migrates to specific nuclear foci early in infection supposely to prepare the sites for viral replication by targeting and ubiquitinating host proteins.
Similarity
Belongs to the alphabaculovirus IE2 protein family.
Mass
42.905 kDa
Sequence
MSRINNADTPTNRRNLSLARGRRRLTYSPSTPMPTPRQTRAPMPTPRQRRSLTPEHVVGDRNAPLRASYTINNSRYNVHGDAEFNPPEDDDDSIIFTDHAAEQARQRAVNLHESLTTTPRSPDYSPVHSPSGQVIDSDDYNSDDDERMLEQILLESAEPPQTPQPAPEPQEDVEVLCHICSCTFTDIKNYNSNFVTSSECNHAVCFKCYVSIVFNKEAYKCSICNRTTLTCRAYNRAGYVELSTVRTVRDNKLIKQHWMQLTESNMPHNRDKTIIEELQLELADLRATTARAHHEVNMIKSDNLLLQQQVDFKNLELQQELNAKVKLQKQNDTLSAANTFLQNQLDAQVAESKIKMDQFVRQHEAFLKKFKSSVM

Gene
IE2
Protein
E3 ubiquitin-protein ligase IE2
Organism
Choristoneura fumiferana nuclear polyhedrosis virus
Length
348 amino acids
Function
RING-finger E3 ubiquitin ligase that plays an important regulatory role during the initial stages of infection. Migrates to specific nuclear foci early in infection supposely to prepare the sites for viral replication by targeting and ubiquitinating host proteins.
Similarity
Belongs to the alphabaculovirus IE2 protein family.
Mass
39.281 kDa
Sequence
MSRQINANTPVSRRRSGLRGRRLSYSPEDAVPTPAPRFSILEARRAADRPAEERMRAWHVIGDTSEPVTLRFVHNNAQYTVHGNAPFNTADFQEERDSQETEAANRAHQRAVHLHEHLHEVQETAAPLPNYSPVHSPDLTVMEDLETPRQRFETMFHAVDAESEDEAVPLPQVDMAVFCHICSCFFTDIKNYNSSFVTTSECNHAVCFKCYTSIMFDKELFKCSMCNRATPTCRVYNHKGFVELLPTRAVRDKQAIKTHWAQLLDNNMSDSKVPEQNDVQKLQAELAELRAEMASMRAEMASKQLGATMALENRRGSSSSGASSSSTSTSSSSSSSWLWECLLNTRNY